Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nathan H. Murray"'
A bioluminescent and homogeneous assay for monitoring GPCR-mediated cAMP modulation and PDE activity
Autor:
Dareen Mikheil, Matthew A. Larsen, Kevin Hsiao, Nathan H. Murray, Tim Ugo, Hui Wang, Said A. Goueli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract 3′,5′-Cyclic adenosine monophosphate (cAMP), the first identified second messenger, is implicated in diverse cellular processes involving cellular metabolism, cell proliferation and differentiation, apoptosis, and gene expression. cAMP i
Externí odkaz:
https://doaj.org/article/0d8ae422e30d4d9aadcd8bb8dfd6c70d
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 11, Pp 298-300 (2014)
In the crystal structure of the title co-crystal, C25H32N4O2·C8H6O4, isophthalic acid and [propane-1,3-diylbis(piperidine-4,1-diyl)]bis(pyridin-4-ylmethanone) molecules are connected into supramolecular chains aligned along the c axis by O—H...N h
Externí odkaz:
https://doaj.org/article/c707f8485de445f78799faf520a3d308
Autor:
Nathan H. Murray, Christopher R. M. Asquith, Zixiang Fang, Michael P. East, Naomi Ptak, Robert W. Smith, James D. Vasta, Chad A. Zimprich, Cesear R. Corona, Matthew B. Robers, Gary L. Johnson, Craig A. Bingman, David J. Pagliarini
Publikováno v:
Nature Chemical Biology. 19:230-238
Autor:
Nathan H. Murray, Adam Lewis, Juan P. Rincon Pabon, Michael L. Gross, Katherine Henzler-Wildman, David J. Pagliarini
Publikováno v:
ACS chemical biology. 17(8)
COQ8A is an atypical kinase-like protein that aids the biosynthesis of coenzyme Q, an essential cellular cofactor and antioxidant. COQ8A's mode of action remains unclear, in part due to the lack of small molecule tools to probe its function. Here, we
Autor:
Jonathan M. Schmitz, John F. Wolters, Nathan H. Murray, Rachel M. Guerra, Craig A. Bingman, Chris Todd Hittinger, David J. Pagliarini
Chalcone isomerases (CHIs) have well-established roles in the biosynthesis of plant flavonoid metabolites.Saccharomyces cerevisiaepossesses two predicted CHI-like proteins, Aim18p (encoded by YHR198C) and Aim46p (YHR199C), but it lacks other enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::063b6248ad5948edda05ae970a2756ab
https://doi.org/10.1101/2022.11.15.516536
https://doi.org/10.1101/2022.11.15.516536
Autor:
Jonathan M. Schmitz, John F. Wolters, Nathan H. Murray, Rachel M. Guerra, Craig A. Bingman, Chris Todd Hittinger, David J. Pagliarini
Publikováno v:
Journal of Biological Chemistry. 299:102981
Autor:
Nathan H. Murray, Adam Lewis, Christopher R. M. Asquith, Juan P. Rincon Pabon, Zixiang Fang, Naomi Ptak, Robert W. Smith, James D. Vasta, Chad A. Zimprich, Cesear R. Corona, Matthew B. Robers, Craig A. Bingman, Michael L. Gross, Katherine Henzler-Wildman, David J. Pagliarini
Small molecule tools have enabled mechanistic investigations and therapeutic targeting of the protein kinase-like (PKL) superfamily. However, such tools are still lacking for many PKL members, including the highly conserved and disease-related UbiB f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::890a547dcd8a5a8bec39b5c8713faef6
https://doi.org/10.1101/2022.03.22.485346
https://doi.org/10.1101/2022.03.22.485346
Publikováno v:
Journal of Biological Chemistry. 294:6333-6343
Growth differentiation factor 8 (GDF8; also known as myostatin) and GDF11 are closely related members of the transforming growth factor β (TGF-β) family. GDF8 strongly and negatively regulates skeletal muscle growth, and GDF11 has been implicated i
Autor:
Gessica Vasco, Franco Taroni, A. Nazli Basak, Filippo M. Santorelli, Matthis Synofzik, Claire Ewenczyk, Michel Koenig, Ginevra Zanni, Bart P.C. van de Warrenburg, Selina Reich, Andreas Traschütz, Thomas Klopstock, Lydie Burglen, Enrico Bertini, Matthieu Bereau, Stefania Magri, Willem De Ridder, Anna Heinzmann, Stephanie Demuth, Hasmet Hanagasi, Jonathan Baets, Ute Grasshoff, David J. Pagliarini, Alexandra Durr, Craig A. Bingman, Tommaso Schirinzi, Lucia Laugwitz, Jan Kern, Christelle Rougeot, Hélène Puccio, Christos Ganos, Rita Horvath, Peter De Jonghe, Benjamin Bender, Ludger Schöls, Renato P. Munhoz, Tobias B. Haack, Mathieu Anheim, Felix Distelmaier, Alessandro Malandrini, Semra Hız Kurul, Nathan H. Murray
Publikováno v:
Annals of Neurology
Annals of neurology
Ann Neurol
Annals of Neurology, 88, 2, pp. 251-263
Annals of neurology 88(2), 251-263 (2020). doi:10.1002/ana.25751
Annals of Neurology, 88, 251-263
Annals of neurology
Ann Neurol
Annals of Neurology, 88, 2, pp. 251-263
Annals of neurology 88(2), 251-263 (2020). doi:10.1002/ana.25751
Annals of Neurology, 88, 251-263
Objective: to foster trial-readiness of coenzyme Q8A (COQ8A)-ataxia, we map the clinicogenetic, molecular, and neuroimaging spectrum of COQ8A-ataxia in a large worldwide cohort, and provide first progression data, including treatment response to coen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2447fab1657759c2727fd84df8830141
https://doi.org/10.1002/ana.25751
https://doi.org/10.1002/ana.25751
Autor:
Natalia Romero-Sandoval, John Shinners, Miguel Martin, Natán Enríquez-Ríos, Evangelyn C. Alocilja, Nathan H. Murray, Héctor Javier Sánchez-Pérez, Adriana Gómez-Bustamante, Sergio G Muñoz-Jiménez, Kasey Pryg, Anaximandro Gómez-Velasco, Allied Bencomo-Alerm, Letisia Jonapá-Gómez, Cristina Gordillo-Marroquín
Publikováno v:
Biosensors, Vol 8, Iss 4, p 128 (2018)
Biosensors
Volume 8
Issue 4
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Biosensors
Volume 8
Issue 4
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
A new method using a magnetic nanoparticle-based colorimetric biosensing assay (NCBA) was compared with sputum smear microscopy (SSM) for the detection of pulmonary tuberculosis (PTB) in sputum samples. Studies were made to compare the NCBA against S