Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nathan Gaddis"'
Autor:
Minzhe Guo, Michael P. Morley, Cheng Jiang, Yixin Wu, Guangyuan Li, Yina Du, Shuyang Zhao, Andrew Wagner, Adnan Cihan Cakar, Michal Kouril, Kang Jin, Nathan Gaddis, Joseph A. Kitzmiller, Kathleen Stewart, Maria C. Basil, Susan M. Lin, Yun Ying, Apoorva Babu, Kathryn A. Wikenheiser-Brokamp, Kyu Shik Mun, Anjaparavanda P. Naren, Geremy Clair, Joshua N. Adkins, Gloria S. Pryhuber, Ravi S. Misra, Bruce J. Aronow, Timothy L. Tickle, Nathan Salomonis, Xin Sun, Edward E. Morrisey, Jeffrey A. Whitsett, NHLBI LungMAP Consortium, Yan Xu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Accurate cell type identification is a key and rate-limiting step in single-cell data analysis. Single-cell references with comprehensive cell types, reproducible and functionally validated cell identities, and common nomenclatures are much
Externí odkaz:
https://doaj.org/article/3956b6ba8fe5414badfff8310d969b64
Autor:
Nathan Gaddis, Ravi Mathur, Jesse Marks, Linran Zhou, Bryan Quach, Alex Waldrop, Orna Levran, Arpana Agrawal, Matthew Randesi, Miriam Adelson, Paul W. Jeffries, Nicholas G. Martin, Louisa Degenhardt, Grant W. Montgomery, Leah Wetherill, Dongbing Lai, Kathleen Bucholz, Tatiana Foroud, Bernice Porjesz, Valgerdur Runarsdottir, Thorarinn Tyrfingsson, Gudmundur Einarsson, Daniel F. Gudbjartsson, Bradley Todd Webb, Richard C. Crist, Henry R. Kranzler, Richard Sherva, Hang Zhou, Gary Hulse, Dieter Wildenauer, Erin Kelty, John Attia, Elizabeth G. Holliday, Mark McEvoy, Rodney J. Scott, Sibylle G. Schwab, Brion S. Maher, Richard Gruza, Mary Jeanne Kreek, Elliot C. Nelson, Thorgeir Thorgeirsson, Kari Stefansson, Wade H. Berrettini, Joel Gelernter, Howard J. Edenberg, Laura Bierut, Dana B. Hancock, Eric Otto Johnson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Opioid addiction (OA) is moderately heritable, yet only rs1799971, the A118G variant in OPRM1, has been identified as a genome-wide significant association with OA and independently replicated. We applied genomic structural equation modeling
Externí odkaz:
https://doaj.org/article/a256dcb979ab4a63979d66feec6d2efc
Autor:
Ravi Mathur, Fang Fang, Nathan Gaddis, Dana B. Hancock, Michael H. Cho, John E. Hokanson, Laura J. Bierut, Sharon M. Lutz, Kendra Young, Albert V. Smith, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Edwin K. Silverman, Grier P. Page, Eric O. Johnson
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
GAWMerge is a computational tool that allows users to integrate SNP genotyping data from array techniques or whole-genome sequencing, providing a feasible method to leverage existing cohorts to increase sample size in genetic studies.
Externí odkaz:
https://doaj.org/article/0ca1f1a607004384bdf4ce1cd35b80e5
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Neonatal abstinence syndrome (NAS) is a constellation of signs of withdrawal occurring after birth following in utero exposure to licit or illicit opioids. Despite significant research and public health efforts, NAS remains challenging to diagnose, p
Externí odkaz:
https://doaj.org/article/ecfbdca0622441bd8afab5910eff1547
Autor:
Anna Maria Masci, Scott White, Ben Neely, Maryanne Ardini-Polaske, Carol B. Hill, Ravi S. Misra, Bruce Aronow, Nathan Gaddis, Lina Yang, Susan E. Wert, Scott M. Palmer, Cliburn Chan, LungMAP Consortium
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Immunofluorescent confocal microscopy uses labeled antibodies as probes against specific macromolecules to discriminate between multiple cell types. For images of the developmental mouse lung, these cells are themselves organized
Externí odkaz:
https://doaj.org/article/b5bb7e5ce810447681d958ddcb6a42e3
Autor:
M. Cecilia Ljungberg, Mayce Sadi, Yunguan Wang, Bruce J. Aronow, Yan Xu, Rong J. Kao, Ying Liu, Nathan Gaddis, Maryanne E. Ardini-Poleske, Tipparat Umrod, Namasivayam Ambalavanan, Teodora Nicola, Naftali Kaminski, Farida Ahangari, Ryan Sontag, Richard A. Corley, Charles Ansong, James P. Carson
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 365-372 (2019)
This data is a curated collection of visual images of gene expression patterns from the pre- and post-natal mouse lung, accompanied by associated mRNA probe sequences and RNA-Seq expression profiles. Mammalian lungs undergo significant growth and cel
Externí odkaz:
https://doaj.org/article/ace70f4e17734f9b9527ba67c493d9f9
Publikováno v:
BMJ Nutrition, Prevention & Health, Vol , Iss
Objectives To investigate causality of the association of serum vitamin D with the risk and severity of COVID-19 infection.Design Two-sample Mendelian randomisation study.Setting Summary data from genome-wide analyses in the population-based UK Bioba
Externí odkaz:
https://doaj.org/article/5b429237515b45efaa6e5e460982ba20
Autor:
Nathan, Gaddis, Joshua, Fortriede, Minzhe, Guo, Eric E, Bardes, Michal, Kouril, Scott, Tabar, Kevin, Burns, Maryanne E, Ardini-Poleske, Stephanie, Loos, Daniel, Schnell, Kang, Jin, Balaji, Iyer, Yina, Du, Bing-Xing, Huo, Anukana, Bhattacharjee, Jeff, Korte, Ruchi, Munshi, Victoria, Smith, Andrew, Herbst, Joseph A, Kitzmiller, Geremy C, Clair, James P, Carson, Joshua, Adkins, Edward E, Morrisey, Gloria S, Pryhuber, Ravi, Misra, Jeffrey A, Whitsett, Xin, Sun, Trevor, Heathorn, Benedict, Paten, V B Surya, Prasath, Yan, Xu, Tim, Tickle, Bruce J, Aronow, Nathan, Salomonis
Publikováno v:
American journal of respiratory cell and molecular biology.
An improved understanding of the human lung necessitates advanced systems models informed by an ever-increasing repertoire of molecular omics, cellular, imaging, and pathological datasets. To centralize and standardize information across broad lung r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfd92f60f42256e949d4045e5693141
https://pubmed.ncbi.nlm.nih.gov/36413377
https://pubmed.ncbi.nlm.nih.gov/36413377
Autor:
Shawana Bibi, Nathan Gaddis, Eric O. Johnson, Barry M. Lester, Walter Kraft, Rachana Singh, Norma Terrin, Susan Adeniyi-Jones, Jonathan M. Davis
Publikováno v:
Pediatric research.
The aim of this study was to identify genetic variants associated with NAS through a genome-wide association study (GWAS) and estimate a Polygenic Risk Score (PRS) model for NAS.A prospective case-control study included 476 in utero opioid-exposed te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92f052d64a3c23d2a5944b314f5d18d
https://pubmed.ncbi.nlm.nih.gov/35974158
https://pubmed.ncbi.nlm.nih.gov/35974158
Autor:
Ravi, Mathur, Fang, Fang, Nathan, Gaddis, Dana B, Hancock, Michael H, Cho, John E, Hokanson, Laura J, Bierut, Sharon M, Lutz, Kendra, Young, Albert V, Smith, Edwin K, Silverman, Grier P, Page, Eric O, Johnson
Publikováno v:
Communications biology. 5(1)
Genome-wide association studies (GWAS) have made impactful discoveries for complex diseases, often by amassing very large sample sizes. Yet, GWAS of many diseases remain underpowered, especially for non-European ancestries. One cost-effective approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43312349a5e090122180ba65e8d7190
https://pubmed.ncbi.nlm.nih.gov/35953715
https://pubmed.ncbi.nlm.nih.gov/35953715