Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nathan G Hedrick"'
Autor:
Amanda C Martyn, Krisztian Toth, Robert Schmalzigaug, Nathan G Hedrick, Ramona M Rodriguiz, Ryohei Yasuda, William C Wetsel, Richard T Premont
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomoto
Externí odkaz:
https://doaj.org/article/40a0aacba1ec4d478275acafdc3fda0d
Autor:
Nathan G. Hedrick, Zhongmin Lu, Eric Bushong, Surbhi Singhi, Peter Nguyen, Yessenia Magaña, Sayyed Jilani, Byung Kook Lim, Mark Ellisman, Takaki Komiyama
Publikováno v:
Nature Neuroscience. 25:726-737
Learning induces the formation of new excitatory synapses in the form of dendritic spines, but their functional properties remain unknown. Here, using longitudinal in vivo two-photon imaging and correlated electron microscopy of dendritic spines in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5159992b31d232749590bb7dbba7c3f8
https://doi.org/10.1038/s41593-022-01086-6
https://doi.org/10.1038/s41593-022-01086-6
Autor:
Anne E. West, Michelle R. Lyons, Matthew V. Green, Fang Liu, Ryohei Yasuda, Liang-Fu Chen, Arthy Narayanan, Ashley B. Williams, Nathan G. Hedrick
Publikováno v:
J Biol Chem
N-Methyl-d-aspartate type glutamate receptors (NMDARs) are key mediators of synaptic activity-regulated gene transcription in neurons, both during development and in the adult brain. Developmental differences in the glutamate receptor ionotropic NMDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7421bebc3fa1f0452dcf6cd90ccf4e4e
https://doi.org/10.1074/jbc.ra119.010266
https://doi.org/10.1074/jbc.ra119.010266
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 20, iss 8
Nature neuroscience, vol 20, iss 8
Motor learning is accompanied by widespread changes within the motor cortex, but it is unknown whether these changes are ultimately funneled through a stable corticospinal output channel or whether the corticospinal output itself is plastic. We inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5eb9bd13d62a9be802d08925b9ccb9
http://europepmc.org/articles/PMC5656286
http://europepmc.org/articles/PMC5656286
Autor:
Hitomi Matsuno, Takeo Saneyoshi, Akio Suzuki, Yasunori Hayashi, Hideji Murakoshi, Margaret M. Stratton, Nathan G. Hedrick, Ryohei Yasuda, Rory O’Connell, Emily Agnello
Publikováno v:
Neuron
Long-term synaptic plasticity requires a mechanism that converts short Ca(2+) pulses into persistent biochemical signaling to maintain the changes in the synaptic structure and function. Here, we present a novel mechanism of a positive feedback loop,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddcf5c48710bd7e336d1e0650e92cfe4
https://europepmc.org/articles/PMC6669903/
https://europepmc.org/articles/PMC6669903/
Publikováno v:
Neuron. 92:705-721
The relationship between the brain and the environment is flexible, forming the foundation for our ability to learn. Here we review the current state of our understanding of the modifications in the sensorimotor pathway related to sensorimotor learni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a53e589360ec34bc7fa9a517d99eddc
https://doi.org/10.1016/j.neuron.2016.10.029
https://doi.org/10.1016/j.neuron.2016.10.029
Autor:
Nathan G. Hedrick, James O. McNamara, Charles E. Hall, Stephen C. Harward, Hideji Murakoshi, Ryohei Yasuda
Publikováno v:
Nature. 538:104-108
The Rho GTPase proteins Rac1, RhoA and Cdc42 have a central role in regulating the actin cytoskeleton in dendritic spines1, thereby exerting control over the structural and functional plasticity of spines2, 3, 4, 5 and, ultimately, learning and memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c8d0dd357fc5ec569a4ab90ef7de00
https://doi.org/10.1038/nature19784
https://doi.org/10.1038/nature19784
Autor:
Robert Schmalzigaug, Ryohei Yasuda, Richard T. Premont, Amanda C. Martyn, William C. Wetsel, Krisztián Tóth, Nathan G. Hedrick, Ramona M. Rodriguiz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da12ca62f5069db21bde2e8f6437964a
https://pubmed.ncbi.nlm.nih.gov/29554125
https://pubmed.ncbi.nlm.nih.gov/29554125
Autor:
Ryohei Yasuda, Nathan G. Hedrick
Publikováno v:
Current opinion in neurobiology. 45
While it is generally appreciated that learning involves the structural rearrangement of neuronal circuits, the underlying orchestration of molecular events that drives these changes is not as well understood. Recent studies on the spatiotemporal org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777d284663ab5a3f5d705314bab2249d
https://pubmed.ncbi.nlm.nih.gov/28709063
https://pubmed.ncbi.nlm.nih.gov/28709063
Autor:
Tal Laviv, Barbara L. Hempstead, James O. McNamara, Nathan G. Hedrick, Stephen C. Harward, Ryohei Yasuda, Charles E. Hall, Enhui Pan, Paula Parra-Bueno, Teresa A. Milner
Brain-derived neurotrophic factor (BDNF) and its receptor TrkB are crucial for many forms of neuronal plasticity1, 2, 3, 4, 5, 6, including structural long-term potentiation (sLTP)7, 8, which is a correlate of an animal’s learning7, 9, 10, 11, 12.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c458d8561f3bf9d4e3cdb3db4e2e7cd
https://europepmc.org/articles/PMC5398094/
https://europepmc.org/articles/PMC5398094/