Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nathan Enick"'
Autor:
Chuan Chen, James W. Saville, Michelle M. Marti, Alexandra Schäfer, Mary Hongying Cheng, Dhiraj Mannar, Xing Zhu, Alison M. Berezuk, Anupam Banerjee, Michele D. Sobolewski, Andrew Kim, Benjamin R. Treat, Priscila Mayrelle Da Silva Castanha, Nathan Enick, Kevin D. McCormick, Xianglei Liu, Cynthia Adams, Margaret Grace Hines, Zehua Sun, Weizao Chen, Jana L. Jacobs, Simon M. Barratt-Boyes, John W. Mellors, Ralph S. Baric, Ivet Bahar, Dimiter S. Dimitrov, Sriram Subramaniam, David R. Martinez, Wei Li
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104798- (2022)
Summary: The emergence of SARS-CoV-2 variants of concern (VOCs) requires the development of next-generation biologics with high neutralization breadth. Here, we characterized a human VH domain, F6, which we generated by sequentially panning large pha
Externí odkaz:
https://doaj.org/article/e9a8e86720ca420e9915a6296aa53a18
Autor:
P. Nathan Enick, Joseph P. Brooker, Camille M. Tumiotto, Brittany T. Staines, Joseph J. Eron, Deborah K. McMahon, Rajesh T. Gandhi, John W. Mellors, Michele D. Sobolewski
Publikováno v:
Journal of Virus Eradication, Vol 7, Iss 2, Pp 100043- (2021)
The quantitative viral outgrowth assay (qVOA) is the gold standard for measuring inducible, replication-competent HIV-1. Using MOLT4-R5 and SupT1-R5 cell lines instead of allogeneic blasts and HIV-1 RNA detection rather than p24 enzyme-immunoassay (E
Externí odkaz:
https://doaj.org/article/e18876d0e0a345828a73d0821fe4f652
Autor:
Octavia M. Peck Palmer, Amy Lukanski, P. Nathan Enick, Alan Wells, Jana L. Jacobs, Michele D. Sobolewski, David A. Nace, April L. Kane, Kevin E. Kip, Melissa Crandall, John W. Mellors, Paula L Kip, Katie Mulvey, Kevin D. McCormick, Michael R. Shurin
Publikováno v:
Journal of the American Medical Directors Association
Objective COVID-19 disproportionately impacts residents in long-term care facilities. Our objective was to quantify the presence and magnitude of antibody response in vaccinated, older adult residents at assisted living, personal care, and independen
Autor:
Mary Ann Checkley, Benjamin G. Luttge, Curtis Dobrowolski, David N. Wald, Deborah McMahon, Ghady Haidar, Michele D. Sobolewski, P. Nathan Enick, Joshua Cyktor, John W. Mellors, Jonathan Karn
Treatment with latency-reversing agents (LRAs) alone has been ineffective in reducing HIV-1 reservoirs in persons with HIV-1 (PWH) on antiretroviral therapy (ART), due to inefficiencies in reservoir reactivation and adaptive immune responses. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe83ac9c1d4981b9c3f9a34df02c8a6
https://doi.org/10.1101/2022.09.05.506592
https://doi.org/10.1101/2022.09.05.506592
Autor:
Chuan Chen, James W. Saville, Michelle M. Marti, Alexandra Schäfer, Mary Hongying Cheng, Dhiraj Mannar, Xing Zhu, Alison M. Berezuk, Anupam Banerjee, Michele D. Sobolewski, Andrew Kim, Benjamin R. Treat, Priscila Mayrelle Da Silva Castanha, Nathan Enick, Kevin D McCormick, Xianglei Liu, Cynthia Adams, Margaret Grace Hines, Zehua Sun, Weizao Chen, Jana L. Jacobs, Simon M. Barratt-Boyes, John W. Mellors, Ralph S. Baric, Ivet Bahar, Dimiter S. Dimitrov, Sriram Subramaniam, David R. Martinez, Wei Li
The emergence of SARS-CoV-2 variants of concern (VOCs) requires the development of next-generation biologics that are effective against a variety of strains of the virus. Herein, we characterize a human VH domain, F6, which we generated by sequential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c22cbb1f80d7e11bf83d1b70fe6a83
https://doi.org/10.1101/2022.02.18.481058
https://doi.org/10.1101/2022.02.18.481058
Autor:
Ghady Haidar, Mounzer Agha, Andrew Bilderback, Amy Lukanski, Kelsey Linstrum, Rachel Troyan, Scott Rothenberger, Deborah K McMahon, Melissa D Crandall, Michele D Sobolewksi, P Nathan Enick, Jana L Jacobs, Kevin Collins, Cynthia Klamar-Blain, Bernard J C Macatangay, Urvi M Parikh, Amy Heaps, Lindsay Coughenour, Marc B Schwartz, Jeffrey M Dueker, Fernanda P Silveira, Mary E Keebler, Abhinav Humar, James D Luketich, Matthew R Morrell, Joseph M Pilewski, John F McDyer, Bhanu Pappu, Robert L Ferris, Stanley M Marks, John Mahon, Katie Mulvey, Sundaram Hariharan, Glenn M Updike, Lorraine Brock, Robert Edwards, Richard H Beigi, Paula L Kip, Alan Wells, Tami Minnier, Derek C Angus, John W Mellors
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75(1)
Background We studied humoral responses after coronavirus disease 2019 (COVID-19) vaccination across varying causes of immunodeficiency. Methods Prospective study of fully vaccinated immunocompromised adults (solid organ transplant [SOT], hematologic
Autor:
Joseph M. Pilewski, Mounzer Agha, James D. Luketich, Amy Lukanski, Derek C. Angus, Robert L. Ferris, Fernanda P. Silveira, Tami Minnier, Scott D. Rothenberger, Cynthia Klamar-Blain, Rachel Troyan, Deborah McMahon, John F. McDyer, P. Nathan Enick, Kelsey Linstrum, Paula L Kip, Alan Wells, Amy Heaps, Bhanu Pappu, Ghady Haidar, Matthew R. Morrell, Michelle Sobolewksi, Abhinav Humar, Mary E. Keebler, Andrew Bilderback, John W. Mellors, Jeffrey Dueker, Stanley M. Marks, Marc Schwartz, Kevin Collins, Urvi M. Parikh, Melissa Crandall
ObjectivesImmunocompromised patients were excluded from COVID-19 vaccine clinical trials. The objectives of the study were to measure antibody responses, levels, and neutralization capability after COVID-19 vaccination among immunocompromised patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d0f908fb263e2b6c09d066d28b7a23
https://doi.org/10.1101/2021.06.28.21259576
https://doi.org/10.1101/2021.06.28.21259576
Autor:
Camille Tumiotto, Joseph P. Brooker, P. Nathan Enick, John W. Mellors, Michele D. Sobolewski, Brittany Staines, Joseph J. Eron, Deborah McMahon, Rajesh T. Gandhi
Publikováno v:
Journal of Virus Eradication, Vol 7, Iss 2, Pp 100043-(2021)
Journal of Virus Eradication
Journal of Virus Eradication
The quantitative viral outgrowth assay (qVOA) is the gold standard for measuring inducible, replication-competent HIV-1. Using MOLT4-R5 and SupT1-R5 cell lines instead of allogeneic blasts and HIV-1 RNA detection rather than p24 enzyme-immunoassay (E
Autor:
Andrew J. Kim, Kevin D. McCormick, Chuan Chen, Wei Li, Michele D. Sobolewski, Nathan Enick, Jana L. Jacobs, Cynthia Adams, Zehua Sun, Dimiter S. Dimitrov, John W. Mellors
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) transmission with several emerging variants remain uncontrolled in many countries, indicating the pandemic remains severe. Recent studies showed reduction of neutralization against these em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dd3aed956266c37d2eb28a1803a514e
https://doi.org/10.1101/2021.03.22.436481
https://doi.org/10.1101/2021.03.22.436481
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