Výsledky vyhledávání - "Nathan E. Rainey"

Akademický článek

Synergistic cellular effects including mitochondrial destabilization, autophagy and apoptosis following low-level exposure to a mixture of lipophilic persistent organic pollutants

Autor: Nathan E. Rainey, Ana Saric, Alexandre Leberre, Etienne Dewailly, Christian Slomianny, Guillaume Vial, Harold I. Zeliger, Patrice X. Petit

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-20 (2017)

Abstract Humans are exposed to multiple exogenous environmental pollutants. Many of these compounds are parts of mixtures that can exacerbate harmful effects of the individual mixture components. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is primari

Externí odkaz: https://doaj.org/article/12c798577ea7439c9deaed3a553f1af3

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Akademický článek

Tafazzin Mutation Affecting Cardiolipin Leads to Increased Mitochondrial Superoxide Anions and Mitophagy Inhibition in Barth Syndrome

Autor: Patrice X. Petit, Hector Ardilla-Osorio, Lucile Penalvia, Nathan E. Rainey

Publikováno v: Cells, Vol 9, Iss 10, p 2333 (2020)

Tafazzin is a phospholipid transacylase that catalyzes the remodeling of cardiolipin, a mitochondrial phospholipid required for oxidative phosphorylation. Mutations of the tafazzin gene cause Barth syndrome, which is characterized by mitochondrial dy

Externí odkaz: https://doaj.org/article/36f6638b94a2440fa4052c6c8338b2bc

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Akademický článek

Highlighting Curcumin-Induced Crosstalk between Autophagy and Apoptosis as Supported by Its Specific Subcellular Localization

Autor: Francisco J. Sala de Oyanguren, Nathan E. Rainey, Aoula Moustapha, Ana Saric, Franck Sureau, José-Enrique O’Connor, Patrice X. Petit

Publikováno v: Cells, Vol 9, Iss 2, p 361 (2020)

Curcumin, a major active component of turmeric (Curcuma longa, L.), is known to have various effects on both healthy and cancerous tissues. In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but the mechanism

Externí odkaz: https://doaj.org/article/249c800764034424ba4ebdac86286ac8

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BMFPs, a versatile therapeutic tool for redirecting a preexisting Epstein-Barr virus antibody response toward defined target cells

Autor: Benoît Gamain, Carine Brousse, Nathan E. Rainey, Béré K. Diallo, Clara-Eva Paquereau, Alexandra Desrames, Jolita Ceputyte, Jean-Philippe Semblat, Olivier Bertrand, Stéphane Gangnard, Jean-Luc Teillaud, Arnaud Chêne

Publikováno v: Science Advances
Science Advances, 2022, 8 (6), pp.eabl4363. ⟨10.1126/sciadv.abl4363⟩

Industrial production of therapeutic monoclonal antibodies is mostly performed in eukaryotic-based systems, allowing posttranslational modifications mandatory for their functional activity. The resulting elevated product cost limits therapy access to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13dd8363288f42cdb0b498a8389adc8
https://doi.org/10.1126/sciadv.abl4363

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Highlighting Curcumin-Induced Crosstalk between Autophagy and Apoptosis as Supported by Its Specific Subcellular Localization

Autor: Franck Sureau, Nathan E. Rainey, Patrice X. Petit, José-Enrique O'Connor, Ana Saric, Francisco J. Sala de Oyanguren, Aoula Moustapha

Publikováno v: Cells
Cells, 2020, 9, ⟨10.3390/cells9020361⟩
Cells 2020
Cells 2020, 2020, 9 (2), pp.361. ⟨10.3390/cells9020361⟩
Cells, MDPI, 2020, 9, ⟨10.3390/cells9020361⟩
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Volume 9
Issue 2
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
Cells, Vol 9, Iss 2, p 361 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9004d1b14480e17181353b9ae87f9b15
https://hal.science/hal-03031415

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Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation

Autor: Patrice X. Petit, Gaël Nicolas, Franck Sureau, Aoula Moustapha, Ana Šarić, Nathan E. Rainey

Publikováno v: Cell Death Discovery
Cell Death Discovery, Springer Nature, 2019, 5 (1), pp.150. ⟨10.1038/s41420-019-0234-y⟩
Cell Death Discovery, 2019, 5, ⟨10.1038/s41420-019-0234-y⟩
Cell Death Discovery, Vol 5, Iss 1, Pp 1-15 (2019)
Cell Death Discovery, Springer Nature, 2019, 5, ⟨10.1038/s41420-019-0234-y⟩

Abstract Iron overload, notably caused by hereditary hemochromatosis, is an excess storage of iron in various organs that causes tissue damage and may promote tumorigenesis. To manage that disorder, free iron depletion can be induced by iron chelator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd033542b500867bbe45a1a7e1ade8b
https://hal-cnrs.archives-ouvertes.fr/hal-02413669

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Akademický článek

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Highlighting curcumin-induced crosstalk between autophagy and apoptosis: A biochemical approach coupling impedancemetry, imaging, and flow cytometry

Autor: José-Enrique O'Connor, Nathan E. Rainey, Aoula Moustapha, Patrice X. Petit, Ana Šarić, Franck Sureau, Francisco José Sala de Oyanguren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c761b2327b5f3118a97a7f8f58b2a0d

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Tafazzin Mutation Affecting Cardiolipin Leads to Increased Mitochondrial Superoxide Anions and Mitophagy Inhibition in Barth Syndrome

Autor: Lucile Penalvia, Patrice X. Petit, Nathan E. Rainey, Hector Ardilla-Osorio

Publikováno v: Cells
Cells, Vol 9, Iss 2333, p 2333 (2020)
Volume 9
Issue 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156f9be85e9181f2111c6e451a3d90f4
https://doi.org/10.3390/cells9102333

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