Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nathan D. VanderKraats"'
Autor:
Keith F. Decker, Margaret Akinhanmi, Kyle L. Jung, Jeremy Hoog, César Sánchez, Nathan D. VanderKraats, James I. McDonald, John R. Edwards, Jeffrey F. Hiken, Lisa E. Rois, Matthew J. Ellis
Publikováno v:
Oncogene
Approximately 75% of breast cancers express estrogen receptor α (ERα) and depend on estrogen signals for continued growth. Aromatase inhibitors (AIs) prevent estrogen production and inhibit estrogen receptor signaling, resulting in decreased cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea873e3478e3561b9a5b3631cac325e
https://doi.org/10.1038/onc.2016.397
https://doi.org/10.1038/onc.2016.397
Autor:
Greg Donahue, John van Tuyn, Nathan D. VanderKraats, Peter D. Adams, Tony McBryan, Shelley L. Berger, Parisha P. Shah, Donncha S. Dunican, Richard R. Meehan, Mark E. Drotar, Taranjit Singh Rai, John R. Edwards, David M. Nelson, Hazel A Cruickshanks, Claire Brock
Publikováno v:
Nature Cell Biology. 15:1495-1506
Altered DNA methylation and associated destabilization of genome integrity and function is a hallmark of cancer. Replicative senescence is a tumour suppressor process that imposes a limit on the proliferative potential of normal cells that all cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23f8939ab40af0ec4f6ca47759c2b84
https://doi.org/10.1038/ncb2879
https://doi.org/10.1038/ncb2879
Publikováno v:
Nucleic Acids Research
Methylation of the CpG-rich region (CpG island) overlapping a gene’s promoter is a generally accepted mechanism for silencing expression. While recent technological advances have enabled measurement of DNA methylation and expression changes genome-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c641c4bdd7ea2a11572ecbf596f188e
https://doi.org/10.1093/nar/gkt482
https://doi.org/10.1093/nar/gkt482
A large number of genomic studies are underway to determine which genes are abnormally regulated by methylation in disease. However, our understanding of how disease-specific methylation changes potentially affect expression is poorly understood. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7182d0c836a7792b756f57f66e62a057
https://doi.org/10.1101/063941
https://doi.org/10.1101/063941
Autor:
Jeremy Hoog, James I. McDonald, Kyle L. Jung, John R. Edwards, César Sánchez, Keith F. Decker, Nathan D. VanderKraats, Matthew J. Ellis, Jeffrey F. Hiken, Margaret Akinhanmi
Approximately 75% of breast cancers express estrogen receptor α (ERα) and depend on estrogen signals for continued growth. Aromatase inhibitors (AIs) prevent estrogen production and inhibit estrogen receptor signaling, resulting in decreased cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e4a7ca661e4d829786a36e0e22167f
https://doi.org/10.1101/056770
https://doi.org/10.1101/056770
Autor:
Peter D. Adams, John J. Cole, William Clark, John R. Edwards, Tony McBryan, Nikolay A. Pchelintsev, Kirstin Lund, Nathan D. VanderKraats, Mhairi Copland
Publikováno v:
Genome Biology
Background. \ud Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are neoplastic disorders of hematopoietic stem cells. DNA methyltransferase inhibitors (DNMTi), 5-azacytidine (AzaC) and 5-aza-2’-deoxycytidine (Decitabine), benefit so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3b5f3142b72fc1a8a4ec86732b576d
https://doi.org/10.1186/s13059-014-0406-2
https://doi.org/10.1186/s13059-014-0406-2
Autor:
Nathan D. VanderKraats, Huanmin Zhang, Fei Tian, Keji Zhao, Jeffrey F. Hiken, Jiuzhou Song, Fei Zhan, John R. Edwards
Marek's disease (MD) is characterized as a T cell lymphoma induced by a cell-associated α-herpesvirus, Marek's disease virus type 1 (MDV1). As with many viral infectious diseases, DNA methylation variations were observed in the progression of MD; th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f152f1c14f6905437fc913dddafb20
https://europepmc.org/articles/PMC3674052/
https://europepmc.org/articles/PMC3674052/
Publikováno v:
Neural computation. 23(7)
For any memoryless communication channel with a binary-valued input and a one-dimensional real-valued output, we introduce a probabilistic lower bound on the mutual information given empirical observations on the channel. The bound is built on the Dv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4989be977aeeed50d7ad078af2fa681b
https://pubmed.ncbi.nlm.nih.gov/21492010
https://pubmed.ncbi.nlm.nih.gov/21492010