Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Nathan D. Lawson"'
Autor:
Di Peng, Koji Ando, Melina Hußmann, Marleen Gloger, Renae Skoczylas, Naoki Mochizuki, Christer Betsholtz, Shigetomo Fukuhara, Stefan Schulte-Merker, Nathan D Lawson, Katarzyna Koltowska
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/266b7fcacaf14dba834c05a763f78445
Autor:
Christopher L. Sudduth, Nicola Blum, Patrick J. Smits, Yu Sheng Cheng, Matthew P. Vivero, Matthew P. Harris, Nathan D. Lawson, Arin K. Greene
Publikováno v:
Journal of Vascular Anomalies, Vol 4, Iss 1, p e063 (2023)
Objectives:. Arteriovenous malformation (AVM) is a congenital lesion with a nidus of irregular blood vessels connecting arteries to veins instead of a normal capillary bed. Somatic MAP2K1 activating mutations in endothelial cells cause extracranial A
Externí odkaz:
https://doaj.org/article/cdec7ed1106f41b0bd14e432b7a7b41d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Single cell ATAC-seq (scATAC-seq) has become the most widely used method for profiling open chromatin landscape of heterogeneous cell populations at a single-cell resolution. Although numerous software tools and pipelines have been developed, an easy
Externí odkaz:
https://doaj.org/article/45261f3e9e1742d789686eee14e95c97
Autor:
Di Peng, Koji Ando, Melina Hußmann, Marleen Gloger, Renae Skoczylas, Naoki Mochizuki, Christer Betsholtz, Shigetomo Fukuhara, Stefan Schulte-Merker, Nathan D Lawson, Katarzyna Koltowska
Publikováno v:
eLife, Vol 11 (2022)
The migration of lymphatic endothelial cells (LECs) is key for the development of the complex and vast lymphatic vascular network that pervades most tissues in an organism. In zebrafish, arterial intersegmental vessels together with chemokines have b
Externí odkaz:
https://doaj.org/article/7abc552b14bb451d8b2c54430420bc47
Autor:
Krishna S Ghanta, Zexiang Chen, Aamir Mir, Gregoriy A Dokshin, Pranathi M Krishnamurthy, Yeonsoo Yoon, Judith Gallant, Ping Xu, Xiao-Ou Zhang, Ahmet Rasit Ozturk, Masahiro Shin, Feston Idrizi, Pengpeng Liu, Hassan Gneid, Alireza Edraki, Nathan D Lawson, Jaime A Rivera-Pérez, Erik J Sontheimer, Jonathan K Watts, Craig C Mello
Publikováno v:
eLife, Vol 10 (2021)
Nuclease-directed genome editing is a powerful tool for investigating physiology and has great promise as a therapeutic approach to correct mutations that cause disease. In its most precise form, genome editing can use cellular homology-directed repa
Externí odkaz:
https://doaj.org/article/a4d2a8d974e94e189ee441394236bb61
Autor:
Ayelet Jerafi-Vider, Ivan Bassi, Noga Moshe, Yaara Tevet, Gideon Hen, Daniel Splittstoesser, Masahiro Shin, Nathan D. Lawson, Karina Yaniv
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109255- (2021)
Summary: The formation of new vessels requires a tight synchronization between proliferation, differentiation, and sprouting. However, how these processes are differentially activated, often by neighboring endothelial cells (ECs), remains unclear. He
Externí odkaz:
https://doaj.org/article/652f9d960400488a9c06396894b1e936
Autor:
Christopher L. Sudduth, MD, Nicola Blum, PhD, Yu Sheng Cheng, BS, Matthew P. Vivero, MD, Patrick Smits, PhD, Nathan D. Lawson, PhD, Arin K. Greene, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 6S, Pp 63-63 (2022)
Externí odkaz:
https://doaj.org/article/a4adba5dea1342818e7950ce67ea94d6
Autor:
Nathan D Lawson, Rui Li, Masahiro Shin, Ann Grosse, Onur Yukselen, Oliver A Stone, Alper Kucukural, Lihua Zhu
Publikováno v:
eLife, Vol 9 (2020)
The zebrafish is ideal for studying embryogenesis and is increasingly applied to model human disease. In these contexts, RNA-sequencing (RNA-seq) provides mechanistic insights by identifying transcriptome changes between experimental conditions. Appl
Externí odkaz:
https://doaj.org/article/e87a10f727bd49c295d1e0426811f00b
Autor:
Jianhong Ou, Haibo Liu, Jun Yu, Michelle A. Kelliher, Lucio H. Castilla, Nathan D. Lawson, Lihua Julie Zhu
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background ATAC-seq (Assays for Transposase-Accessible Chromatin using sequencing) is a recently developed technique for genome-wide analysis of chromatin accessibility. Compared to earlier methods for assaying chromatin accessibility, ATAC-
Externí odkaz:
https://doaj.org/article/b50f59b2e5c945e7bbce85528c99519d
Autor:
Karthikeyan Ponnienselvan, Pengpeng Liu, Thomas Nyalile, Sarah Oikemus, Stacy A Maitland, Nathan D Lawson, Jeremy Luban, Scot A Wolfe
Publikováno v:
Nucleic Acids Research.
Prime editing systems have enabled the incorporation of precise edits within a genome without introducing double strand breaks. Previous studies defined an optimal primer binding site (PBS) length for the pegRNA of ∼13 nucleotides depending on the