Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nathan D. Camp"'
Autor:
Rene Yu-Hong Cheng, King L. Hung, Tingting Zhang, Claire M. Stoffers, Andee R. Ott, Emmaline R. Suchland, Nathan D. Camp, Iram F. Khan, Swati Singh, Ying-Jen Yang, David J. Rawlings, Richard G. James
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long t
Externí odkaz:
https://doaj.org/article/a7a059db17ba4c239eb066542f930a81
Autor:
Ali Sinan Köksal, Kirsten Beck, Dylan R. Cronin, Aaron McKenna, Nathan D. Camp, Saurabh Srivastava, Matthew E. MacGilvray, Rastislav Bodík, Alejandro Wolf-Yadlin, Ernest Fraenkel, Jasmin Fisher, Anthony Gitter
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3607-3618 (2018)
Summary: We present a method for automatically discovering signaling pathways from time-resolved phosphoproteomic data. The Temporal Pathway Synthesizer (TPS) algorithm uses constraint-solving techniques first developed in the context of formal verif
Externí odkaz:
https://doaj.org/article/48caac5bc5e443d090361032f80a4b17
Autor:
Zoi E Sychev, Alex Hu, Terri A DiMaio, Anthony Gitter, Nathan D Camp, William S Noble, Alejandro Wolf-Yadlin, Michael Lagunoff
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006256 (2017)
Kaposi's Sarcoma associated Herpesvirus (KSHV), an oncogenic, human gamma-herpesvirus, is the etiological agent of Kaposi's Sarcoma the most common tumor of AIDS patients world-wide. KSHV is predominantly latent in the main KS tumor cell, the spindle
Externí odkaz:
https://doaj.org/article/36a127881c7841dfb35f2311bdcd832b
Autor:
Rene Yu-Hong Cheng, King L. Hung, Tingting Zhang, Claire M. Stoffers, Andee R. Ott, Emmaline R. Suchland, Nathan D. Camp, Iram F. Khan, Swati Singh, Ying-Jen Yang, David J. Rawlings, Richard G. James
Publikováno v:
Nature communications. 13(1)
Due to their unique longevity and capacity to secrete high levels of protein, plasma B cells have the potential to be used as a cell therapy for protein replacement. Here, we show that ex vivo engineered human plasma cells exhibit single-cell RNA pro
Autor:
Jonathan H. Tsui, Eun Hyun Ahn, Zhipeng Dong, Joseph T. Long, Charles E. Murry, Rakchanok Chavanachat, Zeid Y. Nawas, Nathan J. Sniadecki, Nathan D. Camp, Alejandro Wolf-Yadlin, Andrea Leonard, Alec S.T. Smith, Deok Ho Kim, Jong Seob Choi
Publikováno v:
Biomaterials
Cardiomyocytes differentiated from human induced pluripotent stem cells (hiPSCs) offer tremendous potential when used to engineer human tissues for drug screening and disease modeling; however, phenotypic immaturity reduces assay reliability when tra
Autor:
Zeid Y. Nawas, Jong Seob Choi, Deok Ho Kim, Charles E. Murry, Rakchanok Chavanachat, Jonathan H. Tsui, Nathan D. Camp, Alejandro Wolf-Yadlin, Andrea Leonard, Joseph T. Long, Nathan J. Sniadecki
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) offer tremendous potential for use in engineering human tissues for regenerative therapy and drug screening. However, differentiated cardiomyocytes are phenotypically immature, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0186d06c45ada877120a3b2624e14647
Autor:
Elizabeth C. Curran, Stacey Aggarwal-Howarth, Dorathy-Ann Harris, Kyung Soon Lee, Joseph Hendrickson, John D. Scott, Timothy S. Kountz, Alejandro Wolf-Yadlin, Ji Min Park, Edith H. Wang, Aaron Stewart, Chris Hague, Nathan D. Camp
Publikováno v:
Journal of Biological Chemistry. 291:18210-18221
The α1D-adrenergic receptor (ADRA1D) is a key regulator of cardiovascular, prostate, and central nervous system functions. This clinically relevant G protein-coupled receptor has proven difficult to study, as it must form an obligate modular homodim
Autor:
Alejandro Wolf-Yadlin, Ernest Fraenkel, Rastislav Bodik, Dylan R. Cronin, Aaron McKenna, Saurabh Srivastava, Kirsten Beck, Matthew E. MacGilvray, Jasmin Fisher, Ali Sinan Köksal, Nathan D. Camp, Anthony Gitter
Publikováno v:
Elsevier
Cell Reports, Vol 24, Iss 13, Pp 3607-3618 (2018)
Cell reports
Cell Reports, Vol 24, Iss 13, Pp 3607-3618 (2018)
Cell reports
We present a method for automatically discovering signaling pathways from time-resolved phosphoproteomic data. The Temporal Pathway Synthesizer (TPS) algorithm uses constraint-solving techniques first developed in the context of formal verification t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4e639f51d02ab7df7f5bc01e6ea126
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0001-9249-8181
Autor:
Anthony Gitter, Alex Hu, Nathan D. Camp, William Stafford Noble, Michael Lagunoff, Zoi E. Sychev, Terri A. DiMaio, Alejandro Wolf-Yadlin
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006256 (2017)
PLoS Pathogens
PLoS Pathogens
Kaposi’s Sarcoma associated Herpesvirus (KSHV), an oncogenic, human gamma-herpesvirus, is the etiological agent of Kaposi’s Sarcoma the most common tumor of AIDS patients world-wide. KSHV is predominantly latent in the main KS tumor cell, the spi
Autor:
Inna Goreshnik, Alejandro Wolf-Yadlin, Daniel Cunningham-Bryant, Dustin J. Maly, Jordan Ye, Po-Ssu Huang, John C. Rose, David Baker, Bridget M. Trevillian, Miles Sasha Dickinson, Andrew M. Leidal, Jayanta Debnath, Nathan D. Camp
Publikováno v:
Nature chemical biology, vol 13, iss 1
Nature chemical biology
Nature chemical biology
Synthetic protein switches controlled with user-defined inputs are powerful tools for studying and controlling dynamic cellular processes. To date, these approaches have relied primarily on intermolecular regulation. Here we report a computationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbba15c5312ceb799c40bc249b164784
https://escholarship.org/uc/item/8wm1p9bn
https://escholarship.org/uc/item/8wm1p9bn