Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nathan Caffo"'
Autor:
Richard A. Klinghoffer, Jessica A. Bertout, Alicia Moreno Gonzalez, Sally Ditzler, Jason Frazier, Nathan Caffo, William S. Kerwin, Joseph Casalini
Publikováno v:
Cancer Research. 75:2020-2020
We report the initial clinical findings of a device platform to test multiple therapeutic options simultaneously in individual living tumors within a clinical patient population, detailing for the first time comparative effects of different drugs wit
Autor:
Michael Carleton, Jason Frazier, Richard A. Klinghoffer, Alicia Moreno-Gonzalez, Sally Ditzler, Marc Grenley, James M. Olson, Beryl A. Hatton, Joseph Casalini, William S. Kerwin, Nathan Caffo, Ilona Tretyak, Joyoti Dey, Nathan Hedin
Publikováno v:
Clinical Cancer Research. 21:A39-A39
Assessment of anti-cancer drug efficacy is an imprecise and challenging undertaking. Early candidate selection is typically based on results from systemically treated animal models and later by performance in human trials where patients are exposed t
Abstract 3129: A platform to assess multiple therapy options simultaneously in a patient's own tumor
Autor:
Nathan Caffo, Joyoti Dey, Nathan Hedin, Richard A. Klinghoffer, Beryl A. Hatton, Michael Carleton, Ilona Tretyak, Sally Ditzler, Jason Frazier, Alicia Moreno-Gonzalez, James M. Olson, Marc Grenley, Daniel T. Pierce, Joseph Casalini, Ellen Filvaroff
Publikováno v:
Cancer Research. 74:3129-3129
Proper selection of anti-cancer agents at the earliest stage of patient treatment following diagnosis of disease relapse is expected to substantially impact clinical response to treatment. Currently, genomic approaches to personalized cancer treatmen
Autor:
Nathan Hedin, Richard A. Klinghoffer, Neil Bence, Beryl A. Hatton, Stephen J. Blakemore, Mark Manfredi, Nathan Caffo, Marc Grenley, Marc Hyer
Publikováno v:
Cancer Research. 73:4153-4153
Presage technology enables simultaneous analysis of multiple cancer drug candidates, drug concentrations, and drug combinations within a single living tumor. The platform employs arrayed tumor microinjection technology that delivers multiple spatiall