Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Nathan C. Peters"'
Autor:
Chukwunonso O. Nzelu, Claudio Meneses, Christina Bowhay, Iliano V. Coutinho-Abreu, Emily Bennett, Somayeh Bahrami, Brian Bonilla, Shaden Kamhawi, Jesus G. Valenzuela, Nathan C. Peters
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Background Vector sand fly colonies are a critical component of studies aimed at improving the understanding of the neglected tropical disease leishmaniasis and alleviating its global impact. However, among laboratory-colonized arthropod vec
Externí odkaz:
https://doaj.org/article/24fcb8ccaa1143dfb149620df290f82c
Autor:
Matheus B. Carneiro, Nathan C. Peters
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intracellular phagosomal pathogens represent a formidable challenge for innate immune cells, as, paradoxically, these phagocytic cells can act as both host cells that support pathogen replication and, when properly activated, are the critical cells t
Externí odkaz:
https://doaj.org/article/c2b87db76fe9407ebedaf501f8e4a349
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Leishmaniasis is a health-threatening vector-borne disease in almost 90 different countries. While a prophylactic human vaccine is not yet available, the fact that recovery from leishmaniasis establishes lifelong immunity against secondary infection
Externí odkaz:
https://doaj.org/article/96196fdb459f4d33a582c7a413527d22
Autor:
Leah S Hohman, Zhirong Mou, Matheus B Carneiro, Gabriel Ferland, Rachel M Kratofil, Paul Kubes, Jude E Uzonna, Nathan C Peters
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009944 (2021)
Intracellular infection with the parasite Leishmania major features a state of concomitant immunity in which CD4+ T helper 1 (Th1) cell-mediated immunity against reinfection coincides with a chronic but sub-clinical primary infection. In this setting
Externí odkaz:
https://doaj.org/article/4c6912c0c3984579bab3f79f849cf3a1
Autor:
Adam J. Ranson, Matheus B. Carneiro, Benjamin Perks, Robert Penner, Leon Melo, Johnathan Canton, Jackson Egen, Nathan C. Peters
Publikováno v:
The Journal of Immunology.
Recruited neutrophils are among the first phagocytic cells to interact with the phagosomal pathogen Leishmania following inoculation into the mammalian dermis. Analysis of Leishmania-infected neutrophils has revealed alterations in neutrophil viabili
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006571 (2017)
Quantitation of the nonlinear heterogeneities in Leishmania parasites, sand fly vectors, and mammalian host relationships provides insights to better understand leishmanial transmission epidemiology towards improving its control. The parasite manipul
Externí odkaz:
https://doaj.org/article/4ac24b3e4c1b4bd3986a8d62527cbb37
Autor:
Nathan C Peters, Antonio J Pagán, Phillip G Lawyer, Timothy W Hand, Eric Henrique Roma, Lisa W Stamper, Audrey Romano, David L Sacks
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004538 (2014)
In contrast to the ability of long-lived CD8(+) memory T cells to mediate protection against systemic viral infections, the relationship between CD4(+) T cell memory and acquired resistance against infectious pathogens remains poorly defined. This is
Externí odkaz:
https://doaj.org/article/a91e9808085c422a8c11adf6e270571a
Autor:
Leah S. Hohman, Nathan C. Peters
Publikováno v:
Trends in Parasitology. 35:423-435
The generation of an efficacious vaccine that elicits protective CD4+ T cell-mediated immunity has been elusive. The lack of a vaccine against the Leishmania parasite is particularly perplexing as infected individuals acquire life-long immunity to re
Autor:
Nathan C. Peters, Gabriel Ferland, Leah S. Hohman, Zhirong Mou, Paul Kubes, Jude E. Uzonna, Rachel M. Kratofil, Matheus B. H. Carneiro
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 9, p e1009944 (2021)
PLoS Pathogens, Vol 17, Iss 9, p e1009944 (2021)
Intracellular infection with the parasite Leishmania major features a state of concomitant immunity in which CD4+ T helper 1 (Th1) cell-mediated immunity against reinfection coincides with a chronic but sub-clinical primary infection. In this setting
Autor:
Olena Kamenyeva, David B. Sacks, Nathan C. Peters, Sang Hun Lee, Mariana M. Chaves, Kashinath Ghosh
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008674 (2020)
PLoS Pathogens
PLoS Pathogens
There is substantial experimental evidence to indicate that Leishmania infections that are transmitted naturally by the bites of infected sand flies differ in fundamental ways from those initiated by needle inocula. We have used flow cytometry and in