Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nathan C. Choi"'
Autor:
Shannon M. Mumenthaler, Jasmine Foo, Nathan C. Choi, Nicholas Heise, Kevin Leder, David B. Agus, William Pao, Franziska Michor, Parag Mallick
Publikováno v:
Cancer Informatics, Vol 2015, Iss Suppl. 4, Pp 19-31 (2015)
Externí odkaz:
https://doaj.org/article/7a35e1ea24bf468580d48e9cd67a8d71
Autor:
Jasmine Foo, Danika Lindsay, Erin Spiller, Parag Mallick, David B. Agus, Colleen M. Garvey, Nathan C. Choi, Chun-Te Chiang, Shannon M. Mumenthaler
Publikováno v:
Scientific Reports
Tumor progression results from a complex interplay between cellular heterogeneity, treatment response, microenvironment and heterocellular interactions. Existing approaches to characterize this interplay suffer from an inability to distinguish betwee
Autor:
William Pao, Nathan C. Choi, Kevin Leder, Jasmine Foo, Parag Mallick, Franziska Michor, Shannon M. Mumenthaler, David B. Agus
Publikováno v:
Molecular Pharmaceutics
Many initially successful anticancer therapies lose effectiveness over time, and eventually, cancer cells acquire resistance to the therapy. Acquired resistance remains a major obstacle to improving remission rates and achieving prolonged disease-fre
Autor:
William Pao, Nicholas Heise, Nathan C. Choi, Kevin Leder, Franziska Michor, Shannon M. Mumenthaler, David B. Agus, Jasmine Foo, Parag Mallick
Publikováno v:
Cancer Informatics, Vol 14s4 (2015)
Cancer Informatics, Vol 2015, Iss Suppl. 4, Pp 19-31 (2015)
Cancer Informatics
Cancer Informatics, Vol 2015, Iss Suppl. 4, Pp 19-31 (2015)
Cancer Informatics
Therapeutic resistance arises as a result of evolutionary processes driven by dynamic feedback between a heterogeneous cell population and environmental selective pressures. Previous studies have suggested that mutations conferring resistance to epid
Autor:
Deirdre R. Meldrum, Hariharan Subramanian, David B. Agus, Yiider Tseng, Mark C. Lloyd, Claudia Fischbach, Kevin G. Philips, Thea D. Tlsty, Biana Godin, Jan Liphardt, Guillaume Lambert, Jonathan D. Licht, Matthew R. Dallas, Yue Geng, Jack R. Staunton, Kevin S. Kung, Jasmine Foo, Chira Chen-Tanyolac, Roger H. Johnson, Patti Senechal, Kelly Bethel, Kuldeepsinh Rana, Robert A. Gatenby, Veronica Estrella, Valerie M. Weaver, Scott S. Verbridge, Richard Bonneau, Eric C. Holland, Matthew J. Paszek, Cynthia A. Reinhart-King, Joseph E. Aslan, Wei Chiang Chen, Michael R. King, Alex Greenfield, Ahyoung Joo, Mauro Ferrari, Philippe Gascard, Vivek Nandakumar, Vadim Backman, Franziska Michor, Tyler Jacks, Sharon Gerecht, John F. Marko, Courtney Hemphill, S.P. Ashili, Laimonas Kelbauskas, Casey M. Kraning-Rush, Yolanda Stypula, Stephanie I. Fraley, Brian J. Kwee, Wadih Arap, Thomas V. O'Halloran, Abigail Hielscher, Luis Estévez-Salmerón, Jonathan E. Katz, Steven A. Curley, Arig Ibrahim-Hashim, Robert J. Gillies, Shannon M. Mumenthaler, Christine Will, Peter Kuhn, Srimeenakshi Srinivasan, Dhwanil Damania, Garth W. Tormoen, Parag Mallick, Robert H. Austin, Christian Frantz, Jenny C. Wan, Anna Lyubimova, Michael L. Shuler, Konstantinos Konstantopoulos, Nathan C. Choi, Jonathan W. Wojtkowiak, Carl Kesselman, Paolo Decuzzi, Paul Davies, Laura E. Dickinson, Gregg L. Semenza, Renata Pasqualini, Liyu Liu, Pei Hsun Wu, Barbara L. Hempstead, David Liao, W. Daniel Hillis, Owen J. T. McCarty, Robert Ros, Jenolyn F. Alexander, Alexander Fuhrmann, Jonathan Widom, Steve Oh, William M. Grady, Johnathon N. Lakins, Denis Wirtz, Alexander van Oudenaarden, Christopher S. Poultney
Publikováno v:
Scientific Reports
To investigate the transition from non-cancerous to metastatic from a physical sciences perspective, the Physical Sciences–Oncology Centers (PS-OC) Network performed molecular and biophysical comparative studies of the non-tumorigenic MCF-10A and m
Autor:
William Pao, David B. Agus, Jasmine Foo, Parag Mallick, Franziska Michor, Shannon M. Mumenthaler, Nathan C. Choi
Publikováno v:
Cancer Research. 75:PR16-PR16
Tumor growth is a complex evolutionary process driven by dynamic feedback between a heterogeneous cell population and selection pressures from the tumor microenvironment. Spatio-temporal heterogeneity in the microenvironment can create physical niche