Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Nathan Brot"'
Publikováno v:
Journal of Lipid Research, Vol 5, Iss 4, Pp 538-541 (1964)
The ratio of lipid C14 in plasma of portal vein blood to that in plasma of systemic blood was determined in chickens killed 30, 60, 90, and 150 min after injection of palmitic acid-1-C14 into their gizzards. In other experiments other ratios were det
Externí odkaz:
https://doaj.org/article/dc13cac6c29f4d99a903deffc3e18cc2
Publikováno v:
Journal of Lipid Research, Vol 5, Iss 2, Pp 198-202 (1964)
The esterification of free cholesterol-4-C14 by extracts of acetone powders prepared from the small intestines was measured in normal rats and in rats in which all of the pancreas, except for a small portion along the splenic vessels, was removed. Th
Externí odkaz:
https://doaj.org/article/81c4e142a49a4d4e8823bc3ad7c8a610
Publikováno v:
Journal of Lipid Research, Vol 5, Iss 1, Pp 63-67 (1964)
A very low density, lipoprotein fraction of chyle containing cholesterol-C14 (of which about 70% or more was in the esterified form) was incubated with various rat tissues. The tissues and their incubation media were then analyzed for the C14 contain
Externí odkaz:
https://doaj.org/article/fb3378f8e9054c1698c4a953713062a3
Publikováno v:
Journal of Lipid Research, Vol 3, Iss 2, Pp 207-215 (1962)
Cholesterol-27-C14 in the form of a chylomicron-containing lipoprotein fraction of chyle was injected intravenously into rats. About 75% of the injected sterol-C14 was in the ester and 25% in the free form. Ten minutes after the injection, about 25%
Externí odkaz:
https://doaj.org/article/3896f95d6af143999f30016703e4f182
Publikováno v:
Journal of Lipid Research, Vol 3, Iss 4, Pp 413-415 (1962)
The capacity of plasma of eviscerated rats to esterify free cholesterol was compared with that of plasma of normal control rats by incubating the plasma of these rats with free cholesterol-4-C14 dispersed on Celite and by determining the percentage o
Externí odkaz:
https://doaj.org/article/6e92ad4733dd445794e37eadd989b3f2
Publikováno v:
Drug Metabolism and Disposition. 39:1014-1021
Sulindac is a nonsteroidal, anti-inflammatory drug (NSAID) that has also been studied for its anticancer activity. Recent studies suggest that sulindac and its metabolites act by sensitizing cancer cells to oxidizing agents and drugs that affect mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fbbf4f672c58c1a401ab5b48ed3fe4
https://doi.org/10.1124/dmd.110.037663
https://doi.org/10.1124/dmd.110.037663
Autor:
Venus A. Wong, Gustavo Matute-Bello, Osamu Kajikawa, David R. Park, Raquel Herrero, Naoki Hagimoto, Henry Rosen, Thomas R. Martin, Richard B. Goodman, Steve Mongovin, Yi Wang, Jay W. Heinecke, Xiaoyun Fu, Nathan Brot
Publikováno v:
Journal of Clinical Investigation. 121:1174-1190
Acute lung injury (ALI) is a life-threatening condition in critically ill patients. Injury to the alveolar epithelium is a critical event in ALI, and accumulating evidence suggests that it is linked to proapoptotic Fas/FasL signals. Active soluble Fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072665490b18d26b40c384fd5751b5a7
https://doi.org/10.1172/jci43004
https://doi.org/10.1172/jci43004
Publikováno v:
Proceedings of the National Academy of Sciences. 106:18686-18691
Reactive oxygen intermediates generated by neutrophils kill bacteria and are implicated in inflammatory tissue injury, but precise molecular targets are undefined. We demonstrate that neutrophils use myeloperoxidase (MPO) to convert methionine residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5863f2d84f7aa6ec0a2351db6c3b6c2b
https://doi.org/10.1073/pnas.0909464106
https://doi.org/10.1073/pnas.0909464106
Publikováno v:
Proceedings of the National Academy of Sciences. 105:12224-12229
HDL protects against vascular disease by accepting free cholesterol from macrophage foam cells in the artery wall. This pathway is critically dependent on lecithin:cholesterol acyltransferase (LCAT), which rapidly converts cholesterol to cholesteryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045afc7b22237cb9d55dbfa93ccf7f33
https://doi.org/10.1073/pnas.0802025105
https://doi.org/10.1073/pnas.0802025105
Autor:
Ramez Wassef, Nathan Brot, Stefan H. Heinemann, Ronny Haenold, Toshinori Hoshi, Sophie Neugebauer, Enrico Leipold
Publikováno v:
Free Radical Research. 42:978-988
Methionine sulphoxide reductase A (MSRA) that reduces methionine-S-sulphoxide back to methionine constitutes a catalytic antioxidant mechanism to prevent oxidative damage at multiple sub-cellular loci. This study examined the relative importance of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fb93a53849aa6a9120aeae245c4d64
https://doi.org/10.1080/10715760802566541
https://doi.org/10.1080/10715760802566541