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pro vyhledávání: '"Nathan Brammeier"'
Autor:
Nathan Brammeier, Walter Annette O, Duhl David, Dirksen E. Bussiere, Paul A. Barsanti, Weibo Wang, Zhi-Jie Ni, Eric J. Martin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:157-160
A series of tetrahydro-beta-carbolines were identified by HTS as inhibitors of the kinesin Eg5. Molecular modeling and medicinal chemistry techniques were employed to explore the SAR for this series with a focus of removing potential metabolic liabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ee7399667fa862020291f65163ea75
https://doi.org/10.1016/j.bmcl.2009.11.012
https://doi.org/10.1016/j.bmcl.2009.11.012
