Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nathan Boersen"'
Autor:
Atabak Ghanizadeh Tabriz, Quentin Gonot-Munck, Arnaud Baudoux, Vivek Garg, Richard Farnish, Orestis L. Katsamenis, Ho-Wah Hui, Nathan Boersen, Sandra Roberts, John Jones, Dennis Douroumis
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2230 (2023)
Selective laser sintering (SLS) has drawn attention for the fabrication of three-dimensional oral dosage forms due to the plurality of drug formulations that can be processed. The aim of this work was to employ SLS with a CO2 laser for the manufactur
Externí odkaz:
https://doaj.org/article/863540a770c9412890547b03dc89021e
Autor:
Atabak Ghanizadeh Tabriz, Ho-Wah Hui, Nathan Boersen, Sandra Roberts, John Jones, Dennis Douroumis
Publikováno v:
Molecular Pharmaceutics.
Publikováno v:
Drug Development and Industrial Pharmacy. 42:60-69
Roller compaction is the most commonly employed dry granulation process in the pharmaceutical industry. While this process is increasingly used as an alternative to wet granulation, there are no parameter sets or system of equations to quickly scale
Publikováno v:
Current Pharmaceutical Design. 20:303-324
Solid state manipulation by amorphous solid dispersion has been the subject of intensive research for decades due to their excellent potential for dissolution and bioavailability enhancement. The present review aims to highlight the latest advancemen
Publikováno v:
Drug Development and Industrial Pharmacy. 40:1386-1394
This research aimed at investigating the difference between the powders prior to and after hot melt extrusion. A preliminary assessment was also conducted to gain a better mechanistic understanding of the impact of hot melt extrusion on tabletability
Publikováno v:
Therapeutic Delivery. 2:685-690
"New formulation and manufacturing methods are now available to efficiently and effectively increase solubility and maintain the supersaturation of a thermodynamically metastable state".
Autor:
Garnet E. Peck, Josephine L. P. Soh, Rodolfo Pinal, Nathan Boersen, M. Teresa Carvajal, Kenneth R. Morris
Publikováno v:
Journal of Pharmaceutical Innovation. 2:106-124
This work is an extension of the earlier work from this laboratory aimed at identifying raw material properties critical to the modeling of granule and ribbon properties as part of the optimization of roller (RC) compaction processes. The utility of
Autor:
Patrick J. Marsac, Robert F. Meyer, David R. Johnson, Chad D. Brown, Nathan Boersen, James DiNunzio, Craig A. McKelvey
Publikováno v:
Discovering and Developing Molecules with Optimal Drug-Like Properties ISBN: 9781493913985
Hot-melt extrusion is commonly used to manufacture amorphous solid dispersions. This chapter focuses on the process-formulation-performance interplay of a hot-melt-extruded product within the framework of a hypothetical phase diagram. Special attenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2477b1717b1d61c307e1406b73946bc7
https://doi.org/10.1007/978-1-4939-1399-2_11
https://doi.org/10.1007/978-1-4939-1399-2_11
Publikováno v:
Drug development and industrial pharmacy. 41(9)
While previous research has demonstrated roller compaction operating parameters strongly influence the properties of the final product, a greater emphasis might be placed on the raw material attributes of the formulation. There were two main objectiv
Publikováno v:
Drug development and industrial pharmacy. 40(8)
The objectives of the current study were to understand the dissolution behaviors of amorphous solid dispersions (ASD) using different screening methods and their correlation to the dissolution of formulated products.A poorly soluble compound, compoun