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pro vyhledávání: '"Nathan Angle"'
Autor:
Michael F. Romero, Jennifer DiPiero, Walter F. Boron, Iain A. Drummond, Jing Lu, Jinhua Zhao, Min Hwang Chang, Jennifer O. Liang, Caroline R. Sussman, Christopher M. Daly, Nathan Angle, Consuelo Plata
Publikováno v:
American Journal of Physiology-Cell Physiology. 297:C865-C875
Mutations in the electrogenic Na+/ nHCO3−cotransporter (NBCe1, SLC4A4) cause severe proximal renal tubular acidosis, glaucoma, and cataracts in humans, indicating NBCe1 has a critical role in acid-base homeostasis and ocular fluid transport. To bet
Autor:
Eli J. Holtzman, Brenda L. Smith, Min Hwang Chang, Dganit Dinour, Michael F. Romero, Aaron Knecht, Nathan Angle, I. Serban, Jun Ichi Satoh
Publikováno v:
Journal of Biological Chemistry. 279:52238-52246
In humans and terrestrial vertebrates, the kidney controls systemic pH in part by absorbing filtered bicarbonate in the proximal tubule via an electrogenic Na+/HCO3- cotransporter (NBCe1/SLC4A4). Recently, human genetics revealed that NBCe1 is the ma