Zobrazeno 1 - 10
of 551
pro vyhledávání: '"Nathan A. Smith"'
Autor:
Fushun Wang, Wei Wang, Simeng Gu, Dan Qi, Nathan A. Smith, Weiguo Peng, Wei Dong, Jiajin Yuan, Binbin Zhao, Ying Mao, Peng Cao, Qing Richard Lu, Lee A. Shapiro, S. Stephen Yi, Erxi Wu, Jason H. Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Despite extensive research on astrocytic Ca2+ in synaptic transmission, its contribution to the modulation of sensory transmission during different brain states remains largely unknown. Here, by using two-photon microscopy and whole-cell rec
Externí odkaz:
https://doaj.org/article/64660405c12e4785a602c29e47963d5e
Autor:
Nagsen Gautam, JoEllyn M. McMillan, Devendra Kumar, Aditya N. Bade, Qiaoyu Pan, Tanmay A. Kulkarni, Wenkuan Li, Brady Sillman, Nathan A. Smith, Bhagya L. Dyavar Shetty, Adam Szlachetka, Benson J. Edagwa, Howard E. Gendelman, Yazen Alnouti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Here, the authors provide a mechanism for an improved version of a nanoformulated myristoylated prodrug of cabotegravir (CAB), named NM2CAB, and its bioavailability, stability and pharmacokinetics in mice and rats performed in independent academic an
Externí odkaz:
https://doaj.org/article/2bfe8aa999a043d6aa5d494a5ae8099d
Autor:
Benjamin D. Seadler, MD, Nathan J. Smith, MD, Adhitya Ramamurthi, MD, James Zelten, MS, Karina Alagoa, BS, Lyle D. Joyce, MD PhD, David L. Joyce, MD MBA
Publikováno v:
Surgery Open Science, Vol 20, Iss , Pp 136-139 (2024)
Background: The optimal training program to transform a new resident into a competent and capable surgeon is constantly evolving. Competency-based evaluation represents a change in mindset from quantitative or chronologic metrics for graduate readine
Externí odkaz:
https://doaj.org/article/32f9308975024e5789c81f0b093f7e88
The neuroanatomical organization of the hypothalamus is driven by spatial and topological efficiency
Autor:
Nathan R. Smith, Shabeeb Ameen, Sierra N. Miller, James M. Kasper, Jennifer M. Schwarz, Jonathan D. Hommel, Ahmad Borzou
Publikováno v:
Frontiers in Systems Neuroscience, Vol 18 (2024)
The hypothalamus in the mammalian brain is responsible for regulating functions associated with survival and reproduction representing a complex set of highly interconnected, yet anatomically and functionally distinct, sub-regions. It remains unclear
Externí odkaz:
https://doaj.org/article/732140f6fd0a4fb08b7891489e3ea3f0
Publikováno v:
PLoS ONE, Vol 19, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/a3fa33b378224087bbadcf6e1dd7d3bf
Autor:
Aurélien Stcherbinine, Christopher S. Edwards, Michael D. Smith, Michael J. Wolff, Christopher Haberle, Eman Al Tunaiji, Nathan M. Smith, Kezman Saboi, Saadat Anwar, Lucas Lange, Philip R. Christensen
Publikováno v:
Geophysical Research Letters, Vol 50, Iss 12, Pp n/a-n/a (2023)
Abstract Condensation and sublimation of ices at the surface of the planet is a key part of both the Martian H2O and CO2 cycles, either from a seasonal or diurnal aspect. While most of the ice is located within the polar caps, surface frost is known
Externí odkaz:
https://doaj.org/article/960b724309024c7882e6aea79dd15066
Autor:
Lillian Zheng, MD, Nathan J. Smith, MD, Bi Qing Teng, MS, Aniko Szabo, PhD, David L. Joyce, MD, MBA
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 3, Pp 228-238 (2022)
Objective: To generate a heart failure (HF) readmission prediction model using the Nationwide Readmissions Database to guide management and reduce HF readmissions. Patients and Methods: A retrospective analysis was performed for patients listed for H
Externí odkaz:
https://doaj.org/article/160c9ba0e2c3456cbf176f3ea9ad7f8a
Autor:
Desiree M. Baron, Adam R. Fenton, Sara Saez-Atienzar, Anthony Giampetruzzi, Aparna Sreeram, Shankaracharya, Pamela J. Keagle, Victoria R. Doocy, Nathan J. Smith, Eric W. Danielson, Megan Andresano, Mary C. McCormack, Jaqueline Garcia, Valérie Bercier, Ludo Van Den Bosch, Jonathan R. Brent, Claudia Fallini, Bryan J. Traynor, Erika L.F. Holzbaur, John E. Landers
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110598- (2022)
Summary: Understanding the pathogenic mechanisms of disease mutations is critical to advancing treatments. ALS-associated mutations in the gene encoding the microtubule motor KIF5A result in skipping of exon 27 (KIF5AΔExon27) and the encoding of a p
Externí odkaz:
https://doaj.org/article/41f4ac2c79914783b41ee67f3202e865
Publikováno v:
International Journal of Sports Physiology and Performance. 18:667-673
Purpose: This study examined the influence of blood-flow restriction (BFR) on the distribution of pace, physiological demands, and perceptual responses during self-paced cycling. Methods: On separate days, 12 endurance cyclists/triathletes were instr
Autor:
Evangeline R. Jackson, Ryan J. Duchatel, Dilana E. Staudt, Mika L. Persson, Abdul Mannan, Sridevi Yadavilli, Sarah Parackal, Shaye Game, Wai Chin Chong, W. Samantha N. Jayasekara, Marion Le Grand, Padraic S. Kearney, Alicia M. Douglas, Izac J. Findlay, Zacary P. Germon, Holly P. McEwen, Tyrone S. Beitaki, Adjanie Patabendige, David A. Skerrett-Byrne, Brett Nixon, Nathan D. Smith, Bryan Day, Neevika Manoharan, Sumanth Nagabushan, Jordan R. Hansford, Dinisha Govender, Geoff B. McCowage, Ron Firestein, Meegan Howlett, Raelene Endersby, Nicholas G. Gottardo, Frank Alvaro, Sebastian M. Waszak, Martin R. Larsen, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Andria Rakotomalala, Samuel Meignan, Eddy Pasquier, Nicolas André, Esther Hulleman, David D. Eisenstat, Nicholas A. Vitanza, Javad Nazarian, Carl Koschmann, Sabine Mueller, Jason E. Cain, Matthew D. Dun
Publikováno v:
Cancer Research. :OF1-OF17
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 a