Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Nathan A. Ledeboer"'
Autor:
Hollis R. O’Neal, Jr, MD, MSc, Roya Sheybani, PhD, David R. Janz, MD, MSc, Robert Scoggins, MD, PhD, Tonya Jagneaux, MD, James E. Walker, MD, PhD, Daniel J. Henning, MD, MPH, Elizabeth Rosenman, MD, Simon A. Mahler, MD, MS, Hariharan Regunath, MD, Christopher S. Sampson, MD, D. Clark Files, MD, Richard D. Fremont, MD, Michael J. Noto, MD, PhD, Erica E. Schneider, MD, Wesley R. Shealey, MD, Matthew S. Berlinger, MD, Thomas C. Carver, MD, Morgan K. Walker, MD, Nathan A. Ledeboer, PhD, Ajay M. Shah, PhD, Henry T.K. Tse, PhD, Dino DiCarlo, PhD, Todd W. Rice, MD, MSc, Christopher B. Thomas, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1026 (2024)
OBJECTIVES:. To assess the in vitro IntelliSep test, a microfluidic assay that quantifies the state of immune activation by evaluating the biophysical properties of leukocytes, as a rapid diagnostic for sepsis. DESIGN:. Prospective cohort study. SETT
Externí odkaz:
https://doaj.org/article/63538c9b3c63401cb6b64ae711591b01
Autor:
Chadd K. Kraus, Hollis R. O’Neal, Nathan A. Ledeboer, Todd W. Rice, Wesley H. Self, Richard E. Rothman
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 12, p 1685 (2023)
Potentially septic patients have a huge clinical and economic impact on hospitals and often present to the emergency department (ED) with undifferentiated symptoms. The triage of these patients is complex and has historically relied heavily upon prov
Externí odkaz:
https://doaj.org/article/88513e497f5f449f91b7a5481d5173ed
Autor:
Christopher S. Hollenbeak, PhD, Daniel J. Henning, MD, MPH, Glenn K. Geeting, MD, Nathan A. Ledeboer, PhD, Imran A. Faruqi, MD, Christi G. Pierce, DSc, MSHA, MBA, Christopher B. Thomas, MD, Hollis R. O’Neal, Jr, MD, MS
Publikováno v:
Critical Care Explorations, Vol 5, Iss 7, p e0942 (2023)
OBJECTIVES:. Sepsis causes 270,000 deaths and costs $38 billion annually in the United States. Most cases of sepsis present in the emergency department (ED), where rapid diagnosis remains challenging. The IntelliSep Index (ISI) is a novel diagnostic
Externí odkaz:
https://doaj.org/article/5240e930099f498eb5899bad7b385d61
Autor:
Chadd K. Kraus, H. Bryant Nguyen, Ryan C. Jacobsen, Nathan A. Ledeboer, Larissa S. May, Hollis R. O'Neal Jr., Michael A. Puskarich, Todd W. Rice, Wesley H. Self, Richard E. Rothman
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Objectives Recent research has helped define the complex pathways in sepsis, affording new opportunities for advancing diagnostics tests. Given significant advances in the field, a group of academic investigators from emergency medicine, int
Externí odkaz:
https://doaj.org/article/11d3d6d9ad1a49bea61795950db0b4ce
Autor:
Anna F. Lau, Robert C. Walchak, Heather B. Miller, E. Susan Slechta, Kamal Kamboj, Katherine Riebe, Amy E. Robertson, Jeremy J. Gilbreath, Kaitlin F. Mitchell, Meghan A. Wallace, Alexandra L. Bryson, Joan-Miquel Balada-Llasat, Amanda Bulman, Blake W. Buchan, Carey-Ann D. Burnham, Susan Butler-Wu, Uma Desai, Christopher D. Doern, Kimberly E. Hanson, Christina M. Henderson, Markus Kostrzewa, Nathan A. Ledeboer, Thomas Maier, Preeti Pancholi, Audrey N. Schuetz, Gongyi Shi, Nancy L. Wengenack, Sean X. Zhang, Adrian M. Zelazny, Karen M. Frank
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
ObjectivesRapid and accurate mold identification is critical for guiding therapy for mold infections. MALDI-TOF MS has been widely adopted for bacterial and yeast identification; however, few clinical laboratories have applied this technology for rou
Externí odkaz:
https://doaj.org/article/3ef951886c184360935a132b521c9f31
Autor:
James Ducharme, Wesley H. Self, Tiffany M. Osborn, Nathan A. Ledeboer, Jonathan Romanowsky, Timothy E. Sweeney, Oliver Liesenfeld, Richard E. Rothman
Publikováno v:
Journal of Personalized Medicine, Vol 10, Iss 4, p 266 (2020)
Current diagnostics are insufficient for diagnosis and prognosis of acute infections and sepsis. Clinical decisions including prescription and timing of antibiotics, ordering of additional diagnostics and level-of-care decisions rely on understanding
Externí odkaz:
https://doaj.org/article/60df099f8b004c8fbda51e4e6398989d
Autor:
Swati Kumar, Michael J. Chusid, Rodney E. Willoughby, Peter L. Havens, Sue C. Kehl, Nathan A. Ledeboer, Pippa Simpson, Meredith VanDyke, Elizabeth Davis, Kate Gaffney, Shun-Hwa Li, Michael E. Bose, Kelly J. Henrickson
Publikováno v:
Viruses, Vol 2, Iss 4, Pp 782-795 (2010)
The first wave of the 2009 influenza H1N1 pandemic (H1N1pdm) in Milwaukee, WI has been recognized as the largest reported regional outbreak in the United States. The epidemiologic and clinical characteristics of this large first wave outbreak from Ap
Externí odkaz:
https://doaj.org/article/de861f0cd8aa40d4983e468e7d12e61b
Autor:
Swati Kumar, Michael J. Chusid, Rodney E. Willoughby, Peter L. Havens, Sue C. Kehl, Nathan A. Ledeboer, Shun-Hwa Li, Kelly J. Henrickson
Publikováno v:
Viruses, Vol 1, Iss 1, Pp 72-83 (2009)
On 17 April 2009, novel swine origin influenza A virus (S-OIV) cases appeared within the United States. Most influenza A diagnostic assays currently utilized in local clinical laboratories do not allow definitive subtype determination. Detailed subty
Externí odkaz:
https://doaj.org/article/1bf2a6272b3e4795970401638b44ff15
Autor:
Anthony D. Kappell, Maxwell S. DeNies, Neha H. Ahuja, Nathan A. Ledeboer, Ryan J. Newton, Krassimira R. Hristova
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Urban waterways represent a natural reservoir of antibiotic resistance which may provide a source of transferable genetic elements to human commensal bacteria and pathogens. The objective of this study was to evaluate antibiotic resistance of Escheri
Externí odkaz:
https://doaj.org/article/8d6c8982484b467d89f67edcbad955c8
Publikováno v:
American Journal of Clinical Pathology. 157:781-788
Objectives Aerococcus spp are Gram-positive cocci increasingly recognized as uropathogens. The Clinical and Laboratory Standards Institute recently published specific breakpoints for Aerococcus spp (M45, third edition); however, the standardized meth