Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Nathan A. Baird"'
Autor:
Peter M. Douglas, Nathan A. Baird, Milos S. Simic, Sarah Uhlein, Mark A. McCormick, Suzanne C. Wolff, Brian K. Kennedy, Andrew Dillin
Publikováno v:
Cell Reports, Vol 12, Iss 7, Pp 1196-1204 (2015)
Integrating stress responses across tissues is essential for the survival of multicellular organisms. The metazoan nervous system can sense protein-misfolding stress arising in different subcellular compartments and initiate cytoprotective transcript
Externí odkaz:
https://doaj.org/article/a18f0b3be3334f53973a6697464743b0
Autor:
Mary N. Mwangi, Nathan J. Baird
Publikováno v:
MethodsX, Vol 13, Iss , Pp 102925- (2024)
A long-standing challenge in the study of RNA structure-function dynamics using fluorescence-based methods has been the precise attachment of fluorophores to structured RNA molecules. Despite significant advancements in the field, existing techniques
Externí odkaz:
https://doaj.org/article/0dd081bd49024471aa08cc4060d1c223
Autor:
Hao Yu, Patricia Dranchak, Zhiru Li, Ryan MacArthur, Matthew S. Munson, Nurjahan Mehzabeen, Nathan J. Baird, Kevin P. Battalie, David Ross, Scott Lovell, Clotilde K. S. Carlow, Hiroaki Suga, James Inglese
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
River blindness, a disease affecting millions throughout the tropics, is caused by parasitic worms. Here, Yuet al. report the discovery and structural characterization of potent macrocyclic peptide inhibitors of iPGM, a nematode-specific phosphoglyce
Externí odkaz:
https://doaj.org/article/39345025d3334fe096b7ce4373349fee
Autor:
Mary N. Mwangi, Nathan N. Baird
Publikováno v:
The FASEB Journal. 36
Autor:
Subash C. Jonnalagadda, Chun Wu, Abhinav Illendula, Norman Fultang, Zachary Klase, Brian Y. Chen, Bela Peethambaran, Nathan J. Baird
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0217789 (2019)
PLoS ONE, Vol 14, Iss 5, p e0217789 (2019)
Triple Negative Breast Cancer (TNBC), the most aggressive subtype of breast cancer, is characterized by the absence of hormone receptors usually targeted by hormone therapies like Tamoxifen. Because therapy success and survival rates for TNBC lag far
Publikováno v:
Methods
Interrogating non-coding RNA structures and functions with small molecules is an area of rapidly increasing interest among biochemists and chemical biologists. However, many biochemical approaches to monitoring RNA structures are time-consuming and l
Autor:
Stuart F. J. Le Grice, Wojciech Kasprzak, Nathan J. Baird, Monalisa Swain, Bruce A. Shapiro, Theodore K. Dayie, Regan M. LeBlanc, Abeer A. Ageeli
Publikováno v:
Biophysical Journal. 120:315a
Autor:
Abeer A. Ageeli, Fardokht A. Abulwerdi, Hyeyeon Nam, Wenbo Xu, John S. Schneekloth, Michael Yonkunas, Nathan J. Baird, David L. Spector, Gayatri Arun, Theodore K. Dayie, Stuart F. J. Le Grice
Publikováno v:
ACS chemical biology. 14(2)
Metastasis-associated lung adenocarcinoma transcript 1 ( Malat1/ MALAT1, mouse/human), a highly conserved long noncoding (lnc) RNA, has been linked with several physiological processes, including the alternative splicing, nuclear organization, and ep
Autor:
Nathan J. Baird, Michael Yonkunas
Publikováno v:
RNA
The 3′ end of the ∼7 kb lncRNA MALAT1 contains an evolutionarily and structurally conserved element for nuclear expression (ENE) which confers protection from cellular degradation pathways. Formation of an ENE triple helix is required to support
Autor:
Scott Lovell, James Inglese, Ryan MacArthur, David L. Ross, Hao Yu, N. Mehzabeen, Nathan J. Baird, Clotilde K. S. Carlow, Kevin P. Battalie, Matthew S. Munson, Patricia Dranchak, Zhiru Li, Hiroaki Suga
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Glycolytic interconversion of phosphoglycerate isomers is catalysed in numerous pathogenic microorganisms by a cofactor-independent mutase (iPGM) structurally distinct from the mammalian cofactor-dependent (dPGM) isozyme. The iPGM active site dynamic