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Autor:
Denis J. McCann, Maciej J. Zamek-Gliszczynski, Shelby Anderson, Haitao Hu, Kenneth C. Cassidy, Kimberley Jackson, Trent L. Abraham, Nathan A Furr, Robert J. Barbuch, Kay H. Chow, Palaniappan Kulanthaivel, Jeffrey J. Alberts
Publikováno v:
Drug Metabolism and Disposition. 41:714-726
LY2090314 (3-[9-fluoro-2-(piperidin-1-ylcarbonyl)-1,2,3,4-tetrahydro[1,4]diazepino[6,7,1-hi]indol-7-yl]-4-imidazo[1,2-a]pyridin-3-yl-1H-pyrrole-2,5-dione) is an intravenous glycogen synthase kinase-3 inhibitor in oncology trials. Drug disposition was