Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nathan, WJ"'
Autor:
Nathan, WJ
The accurate repair of DNA damage is essential for protecting cells from undergoing cell death or accumulating mutations. The multi-topical work presented within this thesis focuses on the mechanistic study of DNA repair and sources of genome instabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::5f48effef18517ab1babecb05e92cbdb
https://ora.ox.ac.uk/objects/uuid:71c4029b-4b0f-4347-b38f-5a1267b07dc8
https://ora.ox.ac.uk/objects/uuid:71c4029b-4b0f-4347-b38f-5a1267b07dc8
Publikováno v:
Molecular Cell. 83:523-538.e7
Centromeres are essential for chromosome segregation in most animals and plants yet are among the most rapidly evolving genome elements. The mechanisms underlying this paradoxical phenomenon remain enigmatic. Here, we report that human centromeres in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eef4ac109945f8cfdeb71710f9e3d9a
https://doi.org/10.1016/j.molcel.2023.01.004
https://doi.org/10.1016/j.molcel.2023.01.004
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 06. Date of Electronic Publication: 2024 Sep 06.
Autor:
Wang D; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Wu W; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China., Callen E; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Pavani R; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Zolnerowich N; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Kodali S; Stem Cells and Regenerative Medicine, Center for Cell and Gene Therapy, Department of Molecular and Cellular Biology and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zong D; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Wong N; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Noriega S; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Matos-Rodrigues G; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Chari R; Genome Modification Core, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Kruhlak MJ; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA., Livak F; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA., Ward M; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Caldecott K; Genome Damage and Stability Centre, University of Sussex, Falmer Brighton, UK., Di Stefano B; Stem Cells and Regenerative Medicine, Center for Cell and Gene Therapy, Department of Molecular and Cellular Biology and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
Publikováno v:
Science (New York, N.Y.) [Science] 2022 Dec 02; Vol. 378 (6623), pp. 983-989. Date of Electronic Publication: 2022 Dec 01.
Autor:
Matos-Rodrigues G; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., van Wietmarschen N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Wu W; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Tripathi V; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Koussa NC; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Pavani R; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Callen E; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Belinky F; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Mohammed A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Napierala M; Department of Neurology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA., Usdin K; Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Ansari AZ; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Mirkin SM; Department of Biology, Tufts University, Medford, MA, USA. Electronic address: sergei.mirkin@tufts.edu., Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA. Electronic address: andre_nussenzweig@nih.gov.
Publikováno v:
Molecular cell [Mol Cell] 2022 Oct 06; Vol. 82 (19), pp. 3538-3552.e5. Date of Electronic Publication: 2022 Sep 07.
Autor:
van Wietmarschen N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA. Electronic address: andre_nussenzweig@nih.gov.
Publikováno v:
Current opinion in genetics & development [Curr Opin Genet Dev] 2021 Dec; Vol. 71, pp. 34-38. Date of Electronic Publication: 2021 Jul 17.
Autor:
Wu W; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Hill SE; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Paiano J; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Callen E; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Wang D; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Shinoda K; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., van Wietmarschen N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Colón-Mercado JM; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Zong D; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., De Pace R; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA., Shih HY; National Eye Institute, NIH, Bethesda, MD, USA., Coon S; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA., Parsadanian M; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Pavani R; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Hanzlikova H; Department of Genome Dynamics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK., Park S; Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases and National Cancer Institute, NIH, Bethesda, MD, USA.; NIH Regulome Project, NIH, Bethesda, MD, USA., Jung SK; Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases and National Cancer Institute, NIH, Bethesda, MD, USA.; NIH Regulome Project, NIH, Bethesda, MD, USA., McHugh PJ; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Canela A; The Hakubi Center for Advanced Research and Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan., Chen C; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, NIH, Bethesda, MD, USA., Casellas R; Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases and National Cancer Institute, NIH, Bethesda, MD, USA.; NIH Regulome Project, NIH, Bethesda, MD, USA., Caldecott KW; Department of Genome Dynamics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic. k.w.caldecott@sussex.ac.uk.; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK. k.w.caldecott@sussex.ac.uk., Ward ME; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA. wardme@nih.gov., Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA. andre_nussenzweig@nih.gov.
Publikováno v:
Nature [Nature] 2021 May; Vol. 593 (7859), pp. 440-444. Date of Electronic Publication: 2021 Mar 25.
Autor:
van Wietmarschen N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Sridharan S; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Tubbs A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Chan EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Callen E; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Wu W; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Belinky F; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Tripathi V; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Wong N; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Foster K; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Noorbakhsh J; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Garimella K; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Cruz-Migoni A; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Sommers JA; Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD, USA., Huang Y; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Borah AA; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Smith JT; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Kalfon J; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Kesten N; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Harvard Medical School, Cambridge, MA, USA., Fugger K; DNA Recombination and Repair Laboratory, The Francis Crick Institute, London, UK., Walker RL; Genetics Branch, National Cancer Institute, NIH, Bethesda, MD, USA., Dolzhenko E; Illumina Inc., San Diego, CA, USA., Eberle MA; Illumina Inc., San Diego, CA, USA., Hayward BE; Laboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, MD, USA., Usdin K; Laboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, MD, USA., Freudenreich CH; Department of Biology, Tufts University, Medford, MA, USA., Brosh RM Jr; Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD, USA., West SC; DNA Recombination and Repair Laboratory, The Francis Crick Institute, London, UK., McHugh PJ; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Meltzer PS; Genetics Branch, National Cancer Institute, NIH, Bethesda, MD, USA., Bass AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA. andre_nussenzweig@nih.gov.
Publikováno v:
Nature [Nature] 2020 Oct; Vol. 586 (7828), pp. 292-298. Date of Electronic Publication: 2020 Sep 30.
Autor:
Liu G; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Park SH; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Imbesi M; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Nathan WJ; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Zou X; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois.; 2 Driskill Graduate Program of Life Sciences, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Zhu Y; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Jiang H; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Parisiadou L; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois., Gius D; 1 Department of Radiation Oncology, Robert Lurie Cancer Center, Northwestern University Feinberg School of Medicine , Chicago, Illinois.
Publikováno v:
Antioxidants & redox signaling [Antioxid Redox Signal] 2017 May 20; Vol. 26 (15), pp. 849-863. Date of Electronic Publication: 2016 Sep 08.