Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nathan, Schulte"'
Autor:
Andrew Weickhardt, Diego D'Ávila Paskulin, Teresa Nguyen, Dara L. Aisner, Robert C. Doebele, Fiona Chionh, Niall C. Tebbutt, Jenny Hardingham, Anh T. Le, Nathan Schulte, Marileila Varella-Garcia, John M. Mariadason, Jerry Haney
Publikováno v:
Molecular Cancer Research. 12:111-118
Activated anaplastic lymphoma kinase (ALK) and ROS1 tyrosine kinases, through gene fusions, have been found in lung adenocarcinomas and are highly sensitive to selective kinase inhibitors. This study aimed at identifying the presence of these rearran
Autor:
Barbara Helfrich, Xian Lu, Porntip Kiatsimkul, Marileila Varella-Garcia, Anna E. Barón, Dara L. Aisner, Nathan Schulte, Robert C. Doebele, D. Ross Camidge, Margaret Skokan, Wilbur A. Franklin, DeLee Maxson
Publikováno v:
Cancer. 119:3968-3975
BACKGROUND Patients with anaplastic lymphoma kinase (ALK)-positive non–small cell lung cancer (NSCLC) respond to ALK inhibitors. Clinically, the presence of ≥15% cells with rearrangements identified on break-apart fluorescence in situ hybridizati
Autor:
David J, Miller, Nikola, Miljkovic, Chad, Chiesa, Nathan, Schulte, John B, Callahan, Ben H, Boedeker
Publikováno v:
Studies in health technology and informatics. 163
Difficulty in managing the airway is a major contributor to the morbidity and mortality of the trauma patient. The video laryngoscope, with its camera at the distal tip of the intubation blade, allows the practitioner an improved view of the glottic
Autor:
Fiona Chionh, Marileila Varella-Garcia, Nathan Schulte, Diego D'Ávila Paskulin, Robert C. Doebele, Niall C. Tebbutt, Teresa Nguyen, Dara L. Aisner, Anh T. Le, Andrew Weickhardt, John M. Mariadason
Publikováno v:
Journal of Clinical Oncology. 31:3545-3545
3545 Background: Activation of ROS1 and ALK tyrosine kinases through gene fusions lead to unchecked cell proliferation and transformation. ROS1 and ALK gene fusions were found in about 5% and 2% of lung adenocarcinomas and are highly sensitive to spe
Autor:
D. Ross Camidge, DeLee Maxson, Barbara Helfrich, Margaret Skokan, Porntip Kiatsimkul, Dara L. Aisner, Wilbur A. Franklin, Nathan Schulte, Robert C. Doebele, Marileila Varella-Garcia
Publikováno v:
Journal of Clinical Oncology. 30:7534-7534
7534 Background: ALK rearranged NSCLC responds well to ALK inhibitors. Clinically, >15% cells showing rearrangements by break-apart FISH classifies tumors as ALK(+). Native ALK copy number gain has also been reported. We explored the significance of