Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Nathalie Y.R. Agar"'
Autor:
Yu Mei, Ziming Du, Changchen Hu, Noah F. Greenwald, Malak Abedalthagafi, Nathalie Y.R. Agar, Gavin P. Dunn, Wenya Linda Bi, Sandro Santagata, Ian F. Dunn
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-11 (2017)
Abstract Background Meningiomas are the most common primary intracranial tumors in adults. While a majority of meningiomas are slow growing neoplasms that may cured by surgical resection, a subset demonstrates more aggressive behavior and insidiously
Externí odkaz:
https://doaj.org/article/5a11e57977454c58b67c7e4454c4f671
Publikováno v:
Annual Review of Cancer Biology. 7:265-289
The blood-brain barrier is critically important for the treatment of both primary and metastatic cancers of the central nervous system (CNS). Clinical outcomes for patients with primary CNS tumors are poor and have not significantly improved in decad
Autor:
Eshini Panditharatna, Joana G. Marques, Tingjian Wang, Maria C. Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V. Dharia, Deyao Li, Samantha E. Hoffman, Guillaume Kugener, McKenzie L. Shaw, Hafsa M. Mire, Olivia A. Hack, Joshua M. Dempster, Caleb Lareau, Lingling Dai, Logan H. Sigua, Michael A. Quezada, Ann-Catherine J. Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Federica Piccioni, John G. Doench, David E. Root, Jamie N. Anastas, Kristen L. Jones, Amy Saur Conway, Sylwia Stopka, Michael S. Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P. Jerome, Nathan D. Mathewson, Sirano Dhe-Paganon, Mario L. Suvà, Angel M. Carcaboso, Cinzia Lavarino, Jaume Mora, Quang-De Nguyen, Keith L. Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y.R. Agar, Kimberly Stegmaier, Charles D. Stiles, Michelle Monje, Todd R. Golub, Jun Qi, Mariella G. Filbin
Publikováno v:
Cancer Discovery. :OF1-OF26
Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone
Autor:
Mariella G. Filbin, Jun Qi, Todd R. Golub, Michelle Monje, Charles D. Stiles, Kimberly Stegmaier, Nathalie Y.R. Agar, Sameer Agnihotri, Yang Shi, Keith L. Ligon, Quang-De Nguyen, Jaume Mora, Cinzia Lavarino, Angel M. Carcaboso, Mario L. Suvà, Sirano Dhe-Paganon, Nathan D. Mathewson, William P. Jerome, Puspalata Bashyal, Kijun Song, Hyuk-Soo Seo, Yu Liang, Michael S. Regan, Sylwia Stopka, Amy Saur Conway, Kristen L. Jones, Jamie N. Anastas, David E. Root, John G. Doench, Federica Piccioni, Francisca Vazquez, Amy Goodale, Zohra Kalani, Meghan Wyatt, Ann-Catherine J. Stanton, Michael A. Quezada, Logan H. Sigua, Lingling Dai, Caleb Lareau, Joshua M. Dempster, Olivia A. Hack, Hafsa M. Mire, McKenzie L. Shaw, Guillaume Kugener, Samantha E. Hoffman, Deyao Li, Neekesh V. Dharia, Andrew Groves, Alexander Beck, Li Jiang, Ilon Liu, Maria C. Trissal, Tingjian Wang, Joana G. Marques, Eshini Panditharatna
Supplementary Table from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d35750181befe4f5da4f650722948e9
https://doi.org/10.1158/2159-8290.22541856.v1
https://doi.org/10.1158/2159-8290.22541856.v1
Autor:
Mariella G. Filbin, Jun Qi, Todd R. Golub, Michelle Monje, Charles D. Stiles, Kimberly Stegmaier, Nathalie Y.R. Agar, Sameer Agnihotri, Yang Shi, Keith L. Ligon, Quang-De Nguyen, Jaume Mora, Cinzia Lavarino, Angel M. Carcaboso, Mario L. Suvà, Sirano Dhe-Paganon, Nathan D. Mathewson, William P. Jerome, Puspalata Bashyal, Kijun Song, Hyuk-Soo Seo, Yu Liang, Michael S. Regan, Sylwia Stopka, Amy Saur Conway, Kristen L. Jones, Jamie N. Anastas, David E. Root, John G. Doench, Federica Piccioni, Francisca Vazquez, Amy Goodale, Zohra Kalani, Meghan Wyatt, Ann-Catherine J. Stanton, Michael A. Quezada, Logan H. Sigua, Lingling Dai, Caleb Lareau, Joshua M. Dempster, Olivia A. Hack, Hafsa M. Mire, McKenzie L. Shaw, Guillaume Kugener, Samantha E. Hoffman, Deyao Li, Neekesh V. Dharia, Andrew Groves, Alexander Beck, Li Jiang, Ilon Liu, Maria C. Trissal, Tingjian Wang, Joana G. Marques, Eshini Panditharatna
Supplementary Figure from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f64519af0b30cd43dfae7d183877165
https://doi.org/10.1158/2159-8290.22541865
https://doi.org/10.1158/2159-8290.22541865
Autor:
Mariella G. Filbin, Jun Qi, Todd R. Golub, Michelle Monje, Charles D. Stiles, Kimberly Stegmaier, Nathalie Y.R. Agar, Sameer Agnihotri, Yang Shi, Keith L. Ligon, Quang-De Nguyen, Jaume Mora, Cinzia Lavarino, Angel M. Carcaboso, Mario L. Suvà, Sirano Dhe-Paganon, Nathan D. Mathewson, William P. Jerome, Puspalata Bashyal, Kijun Song, Hyuk-Soo Seo, Yu Liang, Michael S. Regan, Sylwia Stopka, Amy Saur Conway, Kristen L. Jones, Jamie N. Anastas, David E. Root, John G. Doench, Federica Piccioni, Francisca Vazquez, Amy Goodale, Zohra Kalani, Meghan Wyatt, Ann-Catherine J. Stanton, Michael A. Quezada, Logan H. Sigua, Lingling Dai, Caleb Lareau, Joshua M. Dempster, Olivia A. Hack, Hafsa M. Mire, McKenzie L. Shaw, Guillaume Kugener, Samantha E. Hoffman, Deyao Li, Neekesh V. Dharia, Andrew Groves, Alexander Beck, Li Jiang, Ilon Liu, Maria C. Trissal, Tingjian Wang, Joana G. Marques, Eshini Panditharatna
Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ee08482da42079229242adda130064
https://doi.org/10.1158/2159-8290.c.6549756
https://doi.org/10.1158/2159-8290.c.6549756
Autor:
Nathalie Y.R. Agar, Fiona M. Fennessy, Clare M. Tempany, Massimo Loda, Jeffrey N. Agar, Sankha S. Basu, Sudeepa Syamala, Begona G.C. Lopez, Paolo Chetta, Giorgia Zadra, Elizabeth C. Randall
S1. Segmentation map of a subset of lower Gleason tissue specimens, demonstrates regional differences between tumor and normal tissue, and between the two different Gleason grades S2. Example MALDI ion images of 2 long chain acylcarnitine species S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c624948c3a7fb3b5d8b559f9a9ee0b
https://doi.org/10.1158/1541-7786.22512570.v1
https://doi.org/10.1158/1541-7786.22512570.v1
Autor:
Nathalie Y.R. Agar, Fiona M. Fennessy, Clare M. Tempany, Massimo Loda, Jeffrey N. Agar, Sankha S. Basu, Sudeepa Syamala, Begona G.C. Lopez, Paolo Chetta, Giorgia Zadra, Elizabeth C. Randall
Diagnosis of prostate cancer is based on histologic evaluation of tumor architecture using a system known as the “Gleason score.” This diagnostic paradigm, while the standard of care, is time-consuming, shows intraobserver variability, and provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62f2ea0bf35c3250bec50cbf954ecc9c
https://doi.org/10.1158/1541-7786.c.6540276.v1
https://doi.org/10.1158/1541-7786.c.6540276.v1
Autor:
Jann N. Sarkaria, William F. Elmquist, Nicola J. Curtin, Nathalie Y.R. Agar, Alan V. Boddy, Julieann Sludden, Mark A. Schroeder, Brett L. Carlson, Rajendar K. Mittapalli, Sani Kizilbash, David Calligaris, James Murray, Ling Cen, Karen E. Parrish
Supplemental Figure 1. MALDI FTICR mass spectra selected from a pixel with maximum intensity in the MS images of liver (A) and flank tumor (B) sections showing the two first isotopes of rucaparib (peaks labelled 1 and 2, respectively). (C) MALDI FTIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1129c787b2292e6df7e3ef3694a32e7c
https://doi.org/10.1158/1535-7163.22503525.v1
https://doi.org/10.1158/1535-7163.22503525.v1
Autor:
Jann N. Sarkaria, William F. Elmquist, Nathalie Y.R. Agar, Panos Z. Anastasiadis, Ian F. Parney, Aaron J. Johnson, Gaspar J. Kitange, Jeanette E. Eckel-Passow, Paul A Decker, Shulan Tian, James Watters, Laurent Debussche, Cedric Barriere, Fang Jin, Karen E. Parrish, Ann C. Mladek, Isabelle Meaux, Rachael A. Vaubel, Ryan W. Feathers, Shuangling Zhang, David Calligaris, Daniel J. Ma, Minjee Kim
Fig. S1: MDM2 transcript expression. RNA extracted from flank tumor xenografts from 51 PDX models was assessed by qRT-PCR for MDM2 expression in pooled triplicate samples and compared to expression in normal brain (NB). Fig. S2: MDM2 Amplification in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4d4bccac2b614bb5347cc66708c7b1
https://doi.org/10.1158/1535-7163.22505115
https://doi.org/10.1158/1535-7163.22505115