Zobrazeno 1 - 10
of 916
pro vyhledávání: '"Nathalie Vergnolle"'
Autor:
Jin Yan, Claire Racaud-Sultan, Tiffany Pezier, Anissa Edir, Corinne Rolland, Coralie Claverie, Julien Burlaud-Gaillard, Michel Olivier, Philippe Velge, Sonia Lacroix-Lamandé, Nathalie Vergnolle, Agnès Wiedemann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In order to survive and replicate, Salmonella has evolved mechanisms to gain access to intestinal epithelial cells of the crypt. However, the impact of Salmonella Typhimurium on stem cells and progenitors, which are responsible for the abili
Externí odkaz:
https://doaj.org/article/d3ee979c7b5441f8aef55395c3368a2a
Autor:
Giulia Trimaglio, Tamara Sneperger, Benjamin B. A. Raymond, Nelly Gilles, Emmanuelle Näser, Marie Locard-Paulet, Marieke E. Ijsselsteijn, Thomas P. Brouwer, Romain Ecalard, Jessica Roelands, Naoki Matsumoto, André Colom, Myriam Habch, Noel F. C. C. de Miranda, Nathalie Vergnolle, Christel Devaud, Olivier Neyrolles, Yoann Rombouts
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Development and progression of malignancies are accompanied and influenced by alterations in the surrounding immune microenvironment. Understanding the cellular and molecular interactions between immune cells and cancer cells has not only pr
Externí odkaz:
https://doaj.org/article/f3225b2dcc7a4c39953c371ada897c96
Autor:
Liam Emile Rondeau, Bruna Barbosa Da Luz, Alba Santiago, Miriam Bermudez-Brito, Amber Hann, Giada De Palma, Jennifer Jury, Xuanyu Wang, Elena Francisca Verdu, Heather Jean Galipeau, Corinne Rolland, Celine Deraison, Wolfram Ruf, Premysl Bercik, Nathalie Vergnolle, Alberto Caminero
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Imbalances in proteolytic activity have been linked to the development of inflammatory bowel diseases (IBD) and experimental colitis. Proteases in the intestine play important roles in maintaining homeostasis, but exposure of mucosal tissues to exces
Externí odkaz:
https://doaj.org/article/1bb25bf3ffc644a1b2fa596c3883f024
Autor:
Julie Noguerol, Pierre-Jean Roustan, Mikael N’Taye, Léo Delcombel, Corinne Rolland, Laura Guiraud, David Sagnat, Anissa Edir, Chrystelle Bonnart, Alexandre Denadai-Souza, Céline Deraison, Nathalie Vergnolle, Claire Racaud-Sultan
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-15 (2019)
Abstract Background Sexual dimorphism in biological responses is a critical knowledge for therapeutic proposals. However, gender differences in intestinal stem cell physiology have been poorly studied. Given the important role of the protease-activat
Externí odkaz:
https://doaj.org/article/27696bcba2994988b040bc02ef51d5a4
Autor:
Jean-Paul Motta, Alexandre Denadai-Souza, David Sagnat, Laura Guiraud, Anissa Edir, Chrystelle Bonnart, Mireille Sebbag, Perrine Rousset, Ariane Lapeyre, Carine Seguy, Noa Mathurine-Thomas, Heather J. Galipeau, Delphine Bonnet, Laurent Alric, Andre G. Buret, John L. Wallace, Antoine Dufour, Elena F. Verdu, Morley D. Hollenberg, Eric Oswald, Matteo Serino, Celine Deraison, Nathalie Vergnolle
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The roles played by thrombin in the human intestinal mucosa are unclear. Here, the authors show that the commensal microbiota modulates epithelial production of active thrombin, which controls biofilm growth and contributes to protection of the mucos
Externí odkaz:
https://doaj.org/article/68a8589ee36440b4a7b451d28d77ced9
Autor:
Alberto Caminero, Justin L. McCarville, Heather J. Galipeau, Celine Deraison, Steve P. Bernier, Marco Constante, Corinne Rolland, Marlies Meisel, Joseph A. Murray, Xuechen B. Yu, Armin Alaedini, Brian K. Coombes, Premysl Bercik, Carolyn M. Southward, Wolfram Ruf, Bana Jabri, Fernando G. Chirdo, Javier Casqueiro, Michael G. Surette, Nathalie Vergnolle, Elena F. Verdu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Gluten triggers celiac disease in genetically predisposed individuals, but additional unknown mechanisms are required. Here, the authors show that proteases from Pseudomonas aeruginosa can modulate inflammatory pathways that are relevant to the devel
Externí odkaz:
https://doaj.org/article/87da3a2758a84144a45120e2dbe4b18e
Autor:
Nicolas Esquerre, Lilian Basso, Caroline Dubuquoy, Madjid Djouina, Daniel Chappard, Catherine Blanpied, Pierre Desreumaux, Nathalie Vergnolle, Cécile Vignal, Mathilde Body-Malapel
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 185-196 (2019)
Background & Aims: Irritable bowel syndrome (IBS) is a multifactorial disease arising from a complex interplay between genetic predisposition and environmental influences. To date, environmental triggers are not well known. Aluminum is commonly prese
Externí odkaz:
https://doaj.org/article/f6a6961042954a44a97da874739ff057
Autor:
S. Clare Stanford, Steve Alexander, Giuseppe Cirino, Christopher H. George, Paul A. Insel, Dave Kendall, Yong Ji, Reynold A. Panettieri, Hemal H. Patel, Christopher G. Sobey, Barbara Stefanska, Gary Stephens, Mauro Teixeira, Nathalie Vergnolle, Péter Ferdinandy, Amrita Ahluwalia
Publikováno v:
British Journal of Pharmacology. 180:1191-1196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ddd45e05fbfbfecebf063679f7663f
https://doi.org/10.1111/bph.16049
https://doi.org/10.1111/bph.16049
Autor:
Eloïse Mussard, Cécile Pouzet, Virginie Helies, Géraldine Pascal, Sandra Fourre, Claire Cherbuy, Aude Rubio, Nathalie Vergnolle, Sylvie Combes, Martin Beaumont
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101980- (2020)
Intestinal organoids are self-organized 3-dimensional (3D) structures formed by a single layer of polarized epithelial cells. This innovative in vitro model is highly relevant to study physiology of the intestinal epithelium and its role in nutrition
Externí odkaz:
https://doaj.org/article/c61979e5767d400797dd6ce4414ed3cd
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Interstitial cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic inflammatory disease characterized by visceral pain and voiding symptoms. IC/BPS is still an unsolved enigma with ineffective diagnosis criteria and treatment. A main limitation in IC/
Externí odkaz:
https://doaj.org/article/68f280a2507149da83f9aa484793df69