Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Nathalie Thorin-Trescases"'
Autor:
Pauline Labbé, Cécile Martel, Yan-Fen Shi, Augusto Montezano, Ying He, Marc-Antoine Gillis, Marie-Ève Higgins, Louis Villeneuve, Rhian Touyz, Jean-Claude Tardif, Nathalie Thorin-Trescases, Eric Thorin
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Background: Angiopoietin-like 2 (ANGPTL2) is a pro-inflammatory and pro-oxidant circulating protein that predicts and promotes chronic inflammatory diseases such as atherosclerosis in humans. Transgenic murine models demonstrated the deleterious role
Externí odkaz:
https://doaj.org/article/19430de4480f405aba961fc4a3b79862
Autor:
Barnabas Gellen, Nathalie Thorin‐Trescases, Eric Thorin, Elise Gand, Stephanie Ragot, David Montaigne, Yann Pucheu, Kamel Mohammedi, Philippe Gatault, Louis Potier, Evelyne Liuu, Samy Hadjadj, Pierre‐Jean Saulnier, SURDIAGENE Study group
Publikováno v:
ESC Heart Failure, Vol 9, Iss 6, Pp 3909-3919 (2022)
Abstract Aims The hyperglycaemic stress induces the release of inflammatory proteins such as S100A12, one of the endogenous ligands of the receptors for advanced glycation end products (RAGE). Chronic activation of RAGE has multiple deleterious effec
Externí odkaz:
https://doaj.org/article/4a1da66bcc1945ff9fa30a17c364856f
Autor:
Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde, Yan-Fen Shi, Cécile Martel, Carol Yu, Azadeh Alikashani, Maya Mamarbachi, Frédéric Lesage, Samuel Mathieu, Jean-Claude Tardif, Patrick Mathieu, Marie Kmita, Éric Thorin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
Mice knockdown for Angiopoietin-like 2 (Angptl2) exhibit spontaneous aortic valve stenosis associated with a decrease in Notch signalling and an imbalance in cell apoptosis, senescence and proliferation during embryonic valve remodelling stage.
Externí odkaz:
https://doaj.org/article/d3d098d507604c479c8a3cf1d9dd3fe2
Autor:
Olina Dagher, Pauline Mury, Nathalie Thorin-Trescases, Pierre Emmanuel Noly, Eric Thorin, Michel Carrier
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The vascular endothelium occupies a catalog of functions that contribute to the homeostasis of the cardiovascular system. It is a physically active barrier between circulating blood and tissue, a regulator of the vascular tone, a biochemical processo
Externí odkaz:
https://doaj.org/article/69f7819861ea4376a50e3a869bd2738f
Autor:
Fabrice Schneider, Pierre-Jean Saulnier, Elise Gand, Mathieu Desvergnes, Nicolas Lefort, Eric Thorin, Nathalie Thorin-Trescases, Kamel Mohammedi, Stéphanie Ragot, Jean-Baptiste Ricco, Samy Hadjadj
Publikováno v:
Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-12 (2018)
Abstract Background Patients with type 2 diabetes (T2D) face a high amputation rate. We investigated the relationship between the level of amputation and the presence of micro or macro-vascular disease and related circulating biomarkers, Tumor Necros
Externí odkaz:
https://doaj.org/article/867cd405975f4b4ea6fa638d449a3fb6
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12232 (2021)
Cellular senescence is a cell fate primarily induced by DNA damage, characterized by irreversible growth arrest in an attempt to stop the damage. Senescence is a cellular response to a stressor and is observed with aging, but also during wound healin
Externí odkaz:
https://doaj.org/article/b45b6c2e3e5c4052a0edc237be639f16
Autor:
Anthony Pinçon, Olivia De Montgolfier, Nilay Akkoyunlu, Caroline Daneault, Philippe Pouliot, Louis Villeneuve, Frédéric Lesage, Bernard I. Levy, Nathalie Thorin-Trescases, Éric Thorin, Matthieu Ruiz
Publikováno v:
Metabolites, Vol 9, Iss 5, p 104 (2019)
Non-alcoholic fatty liver disease (NAFLD), the leading cause of chronic liver disease, is associated with cognitive decline in middle-aged adults, but the mechanisms underlying this association are not clear. We hypothesized that NAFLD would unveil t
Externí odkaz:
https://doaj.org/article/dd7b93c676294377a62c3c2a2a32a56e
Autor:
Marie-Pier Desjardins, Nathalie Thorin-Trescases, Aboubacar Sidibe, Sacha De Serres, Richard Larivière, Eric Thorin, Mohsen Agharazii
Publikováno v:
Artery Research, Vol 16 (2016)
Externí odkaz:
https://doaj.org/article/8ab7860b91be4aabb99f2fe22f571878
Autor:
Nathalie Thorin-Trescases, Doug Hayami, Carol Yu, Xiaoyan Luo, Albert Nguyen, Jean-François Larouche, Julie Lalongé, Christine Henri, André Arsenault, Mathieu Gayda, Martin Juneau, Jean Lambert, Eric Thorin, Anil Nigam
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164598 (2016)
Pro-inflammatory angiopoietin-like 2 (angptl2) promotes endothelial dysfunction in mice and circulating angptl2 is higher in patients with cardiovascular diseases. We previously reported that a single bout of physical exercise was able to reduce angp
Externí odkaz:
https://doaj.org/article/ca218d7889904e3e9bdb2b78bcea1ba3
Autor:
Albert Nguyen, Maya Mamarbachi, Valérie Turcot, Samuel Lessard, Carol Yu, Xiaoyan Luo, Julie Lalongé, Doug Hayami, Mathieu Gayda, Martin Juneau, Nathalie Thorin-Trescases, Guillaume Lettre, Anil Nigam, Eric Thorin
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153920 (2016)
DNA methylation is believed to regulate gene expression during adulthood in response to the constant changes in environment. The methylome is therefore proposed to be a biomarker of health through age. ANGPTL2 is a circulating pro-inflammatory protei
Externí odkaz:
https://doaj.org/article/ed2a3ceb7561414cb0983d288912cb1d