Protein tyrosine phosphatase 4A3 (PTP4A3) is required for Xenopus laevis cranial neural crest migration in vivo.

Autor: Selma Maacha, Nathalie Planque, Cécile Laurent, Caterina Pegoraro, Océane Anezo, Frédérique Maczkowiak, Anne H Monsoro-Burq, Simon Saule

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84717 (2013)

Uveal melanoma is the most common intraocular malignancy in adults, representing between about 4% and 5% of all melanomas. High expression levels of Protein Tyrosine Phosphatase 4A3, a dual phosphatase, is highly predictive of metastasis development

Externí odkaz: https://doaj.org/article/83c1535152e64ca88ffa2855b1e1db87

Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients

Autor: Simon Saule, Sophie Piperno-Neumann, Emmanuel Barillot, Bernard Asselain, Sergio Roman-Roman, Jean-Paul Thiery, Laurence Desjardins, Xavier Sastre-Garau, Jérôme Couturier, David Gentien, Audrey Rapinat, Benoit Albaud, Cécile Reyes, Corine Plancher, Philippe Hupe, Océane Anezo, Selma Maacha, Licia Silveri, Nathalie Planque, Fabien Valet, Cécile Laurent

Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a261a92bc0c951bd6cbe7ebce877b18
https://doi.org/10.1158/0008-5472.22386720.v1

Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients

Autor: Simon Saule, Sophie Piperno-Neumann, Emmanuel Barillot, Bernard Asselain, Sergio Roman-Roman, Jean-Paul Thiery, Laurence Desjardins, Xavier Sastre-Garau, Jérôme Couturier, David Gentien, Audrey Rapinat, Benoit Albaud, Cécile Reyes, Corine Plancher, Philippe Hupe, Océane Anezo, Selma Maacha, Licia Silveri, Nathalie Planque, Fabien Valet, Cécile Laurent

Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01160ba566425ec090f35ebb1c3e27e9
https://doi.org/10.1158/0008-5472.22386723.v1

Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2

Autor: Océane Anezo, Laura Duciel, Koushik Mandal, David Gentien, Simon Saule, Nathalie Planque, Frédéric M. Coquelle, Jean-Baptiste Manneville, Cécile Laurent

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.2990. ⟨10.1038/s41598-019-39643-y⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)

Uveal melanoma (UM) is an aggressive tumor in which approximately 50% of patients develop metastasis. Expression of the PTP4A3 gene, encoding a phosphatase, is predictive of poor patient survival. PTP4A3 expression in UM cells increases their migrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e93c0e987ce0dd81d692274240ed74
https://hal.archives-ouvertes.fr/hal-02332471

Protein Tyrosine Phosphatase 4A3 (PTP4A3) Promotes Human Uveal Melanoma Aggressiveness Through Membrane Accumulation of Matrix Metalloproteinase 14 (MMP14)

Autor: Nathalie Cassoux, Océane Anezo, Nathalie Planque, Cécile Laurent, S Saule, Sophie Piperno-Neumann, Selma Maacha, Malika Foy, Laurence Mery, Xavier Sastre-Garau, Géraldine Liot

Publikováno v: Investigative ophthalmologyvisual science. 57(4)

PURPOSE To study PTP4A3 phosphatase and MMP14 metalloprotease synergy in uveal melanoma aggressiveness. METHODS Cell membrane localization of matrix metalloprotease 14 (MMP14) in uveal melanoma cells expressing protein tyrosine phosphatase A3 (PTP4A3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8feed9754f6d0ba89c09ee83fbec24
https://pubmed.ncbi.nlm.nih.gov/27096756