Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nathalie Perek"'
Autor:
Frederic Roche, Anne Briançon-Marjollet, Maurice Dematteis, Marie Baldazza, Brigitte Gonthier, Frederique Bertholon, Nathalie Perek, Jean-Louis Pépin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3065 (2024)
Obstructive sleep apnea (OSA) is characterized by intermittent repeated episodes of hypoxia–reoxygenation. OSA is associated with cerebrovascular consequences. An enhanced blood–brain barrier (BBB) permeability has been proposed as a marker of th
Externí odkaz:
https://doaj.org/article/1c17916076fe495ba034d115e7ad2060
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Patients with obstructive sleep apnea/hypopnea (OSA) are at high risk of cerebrovascular diseases leading to cognitive impairment. The oxidative stress generated by intermittent hypoxia (IH) could lead to an increase in blood–brain barrier
Externí odkaz:
https://doaj.org/article/301a8ca8db584126934da7ab4f2e281c
Autor:
Anne Cloé Voirin, Morgane Chatard, Anne Briançon-Marjollet, Jean Louis Pepin, Nathalie Perek, Frederic Roche
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 5062 (2023)
Several sleep-related breathing disorders provoke repeated hypoxia stresses, which potentially lead to neurological diseases, such as cognitive impairment. Nevertheless, consequences of repeated intermittent hypoxia on the blood-brain barrier (BBB) a
Externí odkaz:
https://doaj.org/article/34a9f2043dd34fdabc738ea0065f6e59
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 6, Pp 1231-1248 (2020)
Externí odkaz:
https://doaj.org/article/f4da594ffd9740d99108f678d3fa3d9c
Autor:
Cindy Zolotoff, Laurent Bertoletti, David Gozal, Valentine Mismetti, Pascale Flandrin, Frédéric Roche, Nathalie Perek
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 14, p 3099 (2021)
Obstructive sleep apnea (OSA) is characterized by repeated episodes of intermittent hypoxia (IH) and is recognized as an independent risk factor for vascular diseases that are mediated by a multitude of mechanistic pathophysiological cascades includi
Externí odkaz:
https://doaj.org/article/9e5a4c38bb9f41fe80f3645cb1692c23
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 4, Pp 1592-1602 (2017)
Background/Aims: Understanding cellular mechanisms induced by hypoxia is fundamental to reduce blood-brain barrier (BBB) disruption. Nevertheless, the investigation of hypoxia on cellular pathways is complex with true hypoxia because HIF-1α has a sh
Externí odkaz:
https://doaj.org/article/7ba0720d129b41cf9833d285b3096842
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158010 (2016)
Understanding cellular and molecular mechanisms induced by hypoxic stress is crucial to reduce blood-brain barrier (BBB) disruption in some neurological diseases. Since the brain is a complex organ, it makes the interpretation of in vivo data difficu
Externí odkaz:
https://doaj.org/article/eb61f313830847df8f21412f16fa468f
Publikováno v:
Médecine du Sommeil. 20:77-78
Publikováno v:
Médecine du Sommeil. 20:11
Autor:
Nathalie Perek, Laurent Bertoletti, David Gozal, Cindy Zolotoff, Pascale Flandrin, Valentine Mismetti, Frédéric Roche
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 3099, p 3099 (2021)
Journal of Clinical Medicine, Vol 10, Iss 3099, p 3099 (2021)
Obstructive sleep apnea (OSA) is characterized by repeated episodes of intermittent hypoxia (IH) and is recognized as an independent risk factor for vascular diseases that are mediated by a multitude of mechanistic pathophysiological cascades includi