Human risk associated with exposure to mixtures of antiandrogenic chemicals evaluated using in vitro hazard and human biomonitoring data

Autor: Yanying Ma, Camilla Taxvig, Andrea Rodríguez-Carrillo, Vicente Mustieles, Lena Reiber, Anja Kiesow, Nathalie Michelle Löbl, Mariana F. Fernández, Tina Vicky Alstrup Hansen, Maria João Valente, Marike Kolossa-Gehring, Madlen David, Anne Marie Vinggaard

Publikováno v: Environment International, Vol 173, Iss , Pp 107815- (2023)

Background: Scientific evidence for underestimated toxicity from unintentional exposure to chemical mixtures is mounting. Yet, harmonized approaches on how to assess the actual risk of mixtures is lacking. As part of the European Joint programme ‘H

Externí odkaz: https://doaj.org/article/936f4d3b031f4505a6429853fae53896

On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies

Autor: Marta Axelstad, Ulla Hass, Nathalie Michelle Löbl, Louise Ramhøj, Sofie Christiansen, Terje Svingen, Camilla Victoria Lindgren Schwartz

Publikováno v: Lindgren Schwartz, C, Christiansen, S, Hass, U, Ramhøj, L, Axelstad, M, Michelle Löbl, N & Svingen, T 2021, ' On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies ', Frontiers in Toxicology, vol. 3, 730752 . https://doi.org/10.3389/ftox.2021.730752
Frontiers in Toxicology, Vol 3 (2021)

Areola/nipple retention (NR) is an established biomarker for an anti-androgenic mode of action in rat toxicity studies. It is a mandatory measurement under several OECD test guidelines and is typically assessed in combination with anogenital distance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b7de2756879a1c3d91b52c9b64f48f
https://orbit.dtu.dk/en/publications/3902273d-211f-4c86-8d5e-36d3e6b4523e

Chemical Mixture Calculator - A novel tool for mixture risk assessment

Autor: Anne Marie Vinggaard, Annette Petersen, Julie Boberg, Elsa Nielsen, Bodil Hamborg Jensen, Nathalie Michelle Löbl, Lea Bredsdorff

Publikováno v: Boberg, J, Bredsdorff, L, Petersen, A, Löbl, N M, Jensen, B H, Vinggaard, A M & Nielsen, E E 2021, ' Chemical Mixture Calculator-A novel tool for mixture risk assessment ', Food and Chemical Toxicology, vol. 152, 112167 . https://doi.org/10.1016/j.fct.2021.112167

Humans are continuously exposed to complex chemical mixtures from foods and the environment. Experimental models in vivo and in vitro have increased our knowledge on how we can predict mixture effects. To accommodate a need for tools for efficient mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4c515b0a09340c156ca2289f098033
https://doi.org/10.1016/j.fct.2021.112167

MIraculiX - Strengthened risk assessment of chemicals

Autor: Anne Marie Vinggaard, Terje Svingen, Julie Boberg, Camilla Taxvig, Sofie Christiansen, Henrik Lauritz Frandsen, Mikael Pedersen, Annette Petersen, Lea Bredsdorff, Elsa Nielsen, Bodil Hamborg Jensen, Marianne Dybdahl, Tue Christensen, Sisse Fagt, Birgitte Møller Plesning, Heidi Broksø Letting, Lillian Sztuk, Ulla El-Baroudy, Vivian Jørgensen, Dorte Lykkegaard Korsbech, Mette Voigt Jessen, Anne-Marie Ørngreen, Hanna Katarina Lilith Johansson, Camilla Lindgren Schwartz, Nathalie Michelle Löbl, David Silva Melo, Andreas Kortenkamp, Martin Scholze, Sibylle Ermler, Frederic Chalmel, Paul Fowler, Erik Nørby

Publikováno v: Technical University of Denmark Orbit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::23f47ab4925488b0720ed8531e8472a7
https://orbit.dtu.dk/en/publications/2b0f2827-a287-4713-b994-74acfa79854c