Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nathalie Mesplet"'
Autor:
Laure Joly, Rodolphe Antoine, Nathalie Mesplet, Philippe Dugourd, Amandine Racaud, Jérôme Lemoine
Publikováno v:
Journal of the American Society for Mass Spectrometry. 20:1645-1651
A set of three heparin-derived disaccharide deprotonated ions was isolated in a linear ion trap and subjected to UV laser irradiation in the 220-290 nm wavelength range. The dissociation yields of the deprotonated molecular ions were recorded as a fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b69be0f5504ee5e76b668ff73e2bd49
https://doi.org/10.1016/j.jasms.2009.04.022
https://doi.org/10.1016/j.jasms.2009.04.022
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 59:523-526
Eflucimibe, a novel and highly potent acyl-coenzyme A cholesterol O-acyl-transferase (ACAT) inhibitor, is sparingly soluble in aqueous media and exhibits a very weak natural fluorescence. However, when increasing concentrations of gamma-cyclodextrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7c14253b4b3f488e764d384932e480
https://doi.org/10.1016/j.ejpb.2004.09.011
https://doi.org/10.1016/j.ejpb.2004.09.011
Publikováno v:
Rapid Communications in Mass Spectrometry. 19:297-302
A high-performance liquid chromatography/electrospray ionisation tandem mass spectrometry (HPLC/ESI-MS/MS) method has been developed for the simultaneous determination of eflucimibe, a powerful acyl-coenzyme A cholesterol O-acyltransferase (ACAT) inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c35e50ee19eff3ef747fccf4d4b7445
https://doi.org/10.1002/rcm.1784
https://doi.org/10.1002/rcm.1784
Publikováno v:
Journal of Separation Science. 26:1353-1358
Eflucimibe (F 12511) is a new and promising acyl-coenzyme A cholesterol O-acyltransferase (ACAT) inhibitor, developed at the Pierre Fabre Research Center for the treatment of atherosclerosis. Owing to the synthetic pathway, residual impurities may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f36fc0355048f8a76938503345d1e048
https://doi.org/10.1002/jssc.200301551
https://doi.org/10.1002/jssc.200301551
Publikováno v:
Bioorganic Chemistry. 31:237-247
In one current strategy to develop membrane-soluble pronucleotides, the phosphoramidate derivatives of the approved anti-HIV nucleosides 2 ′ ,3 ′ -didehydro-3 ′ -deoxythymidine (d4T), 3 ′ -azido-3 ′ -deoxythymidine (AZT), (−)-β- l -2 ′
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1f89f22d1eb642bb7586ac8f49028f
https://doi.org/10.1016/s0045-2068(03)00035-x
https://doi.org/10.1016/s0045-2068(03)00035-x
Publikováno v:
ELECTROPHORESIS. 23:1263-1271
As part of our on-going study of the analysis of anti-human immunodeficiency virus (HIV) nucleosides, a capillary electrochromatography (CEC) method has been developed for the concurrent analysis of nucleoside HIV reverse transcriptase inhibitors (NR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4cbab4a87aee28e71eadfc24c5eeba0
https://doi.org/10.1002/1522-2683(200205)23:9<1263::aid-elps1263>3.0.co
https://doi.org/10.1002/1522-2683(200205)23:9<1263::aid-elps1263>3.0.co
Autor:
Xavier Cahours, Claudine Kieda, Nathalie Mesplet, Thanh Thu Tran, Luigi A. Agrofoglio, Philippe Morin
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 26:819-827
An analytical procedure has been developed for the analysis of intracellular didanosine triphosphate (ddATP). An electrospray ionization tandem mass spectrometer (ESI-MS) was interfaced to liquid chromatography (LC) using a mobile phase CH3OH/H2O (25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4e85df73f982c5d5af0b0153c46a61
https://doi.org/10.1016/s0731-7085(01)00457-5
https://doi.org/10.1016/s0731-7085(01)00457-5
Publikováno v:
Journal of chromatography. A. 983(1-2)
To improve the therapeutic potential of anti-HIV nucleoside analogues (d4T, AZT, 3TC and ddI), the delivery of the corresponding monophosphate from neutral, membrane-permeable prodrugs has been realised by the synthesis of lipophilic phosphoramidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3346d5c589e4571308b24b7e515b1d
https://pubmed.ncbi.nlm.nih.gov/12568375
https://pubmed.ncbi.nlm.nih.gov/12568375
Publikováno v:
Electrophoresis. 23(9)
As part of our on-going study of the analysis of anti-human immunodeficiency virus (HIV) nucleosides, a capillary electrochromatography (CEC) method has been developed for the concurrent analysis of nucleoside HIV reverse transcriptase inhibitors (NR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::684b609b79408d9cc6be08f7d4c1589c
https://pubmed.ncbi.nlm.nih.gov/12007125
https://pubmed.ncbi.nlm.nih.gov/12007125
Publikováno v:
Journal of chromatography. A. 927(1-2)
As part of our on-going study of the analysis and quantitation of anti-HIV nucleosides, a capillary electrochromatography (CEC) method has been developed for the simultaneous quantitation of nucleoside HIV reverse transcriptase inhibitors (NRTIs), i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e24b2fb83a85b0419dc8577078e487
https://pubmed.ncbi.nlm.nih.gov/11572385
https://pubmed.ncbi.nlm.nih.gov/11572385