Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Nathalie M, Mazure"'
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon-Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan-Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2262-2267 (2024)
Externí odkaz:
https://doaj.org/article/4674eb9ca9f241b4a3996ff03dc79709
Autor:
Siyong Peng, Yingbo Guo, Marie Irondelle, Abigail Mazzu, Michel Kahi, Paula Ferreira Montenegro, Frédéric Bost, Nathalie M. Mazure
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background Prostate cancer (PCa) ranks as the second most prevalent cancer in men, with advanced stages posing significant treatment challenges. Given its solid tumor nature, PCa is highly susceptible to hypoxia, a condition associated with
Externí odkaz:
https://doaj.org/article/49bbf45345e645cfb3a2d6bd3655b6ea
Autor:
Marc Pujalte‐Martin, Amine Belaïd, Simon Bost, Michel Kahi, Pascal Peraldi, Matthieu Rouleau, Nathalie M. Mazure, Frédéric Bost
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1719-1738 (2024)
Metformin and IACS‐010759 are two distinct antimetabolic agents. Metformin, an established antidiabetic drug, mildly inhibits mitochondrial complex I, while IACS‐010759 is a new potent mitochondrial complex I inhibitor. Mitochondria is pivotal in
Externí odkaz:
https://doaj.org/article/f7c9b6087330477c926a0b2739689af4
Autor:
Ana C. B. Sant'Anna‐Silva, Thomas Botton, Andrea Rossi, Jochen Dobner, Hanene Bzioueche, Nguyen Thach, Lauriane Blot, Sophie Pagnotta, Konrad Kleszczynski, Kerstin Steinbrink, Nathalie M. Mazure, Stéphane Rocchi, Jean Krutmann, Thierry Passeron, Meri K. Tulic
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/9305f8c0f89f41ec8074cb830bcb975d
LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-18 (2023)
Abstract Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome‐wide CRISPR‐Cas9 knockout screen, which revealed the LKB1‐SIK2 module in restraining uveal melanoma tumor
Externí odkaz:
https://doaj.org/article/1a3e75bad0684eebb8afbad93d505cd9
Autor:
Maeva Dufies, Annelies Verbiest, Lindsay S. Cooley, Papa Diogop Ndiaye, Xingkang He, Nicolas Nottet, Wilfried Souleyreau, Anais Hagege, Stephanie Torrino, Julien Parola, Sandy Giuliano, Delphine Borchiellini, Renaud Schiappa, Baharia Mograbi, Jessica Zucman-Rossi, Karim Bensalah, Alain Ravaud, Patrick Auberger, Andréas Bikfalvi, Emmanuel Chamorey, Nathalie Rioux-Leclercq, Nathalie M. Mazure, Benoit Beuselinck, Yihai Cao, Jean Christophe Bernhard, Damien Ambrosetti, Gilles Pagès
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Dufies et al. find high Plk1 expression levels in aggressive clear cell renal cell carcinoma and discover that Plk1 is transcriptionally upregulated in a manner dependent on HIF-2. They also find that high Plk1 expression is correlated to a poor prog
Externí odkaz:
https://doaj.org/article/9cd5ec5c631f454a824bec657b006c8d
Autor:
Stéphane J.C. Mancini, Karl Balabanian, Isabelle Corre, Julie Gavard, Gwendal Lazennec, Marie-Caroline Le Bousse-Kerdilès, Fawzia Louache, Véronique Maguer-Satta, Nathalie M. Mazure, Fatima Mechta-Grigoriou, Jean-François Peyron, Valérie Trichet, Olivier Herault
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Knowledge about the hematopoietic niche has evolved considerably in recent years, in particular through in vitro analyzes, mouse models and the use of xenografts. Its complexity in the human bone marrow, in particular in a context of hematological ma
Externí odkaz:
https://doaj.org/article/cb6393dbb52c4389b81b57399a686a9c
Autor:
Monique Meyenberg Cunha-de Padua, Guilhermina Rodrigues Noleto, Carmen Lucia de Oliveira Petkowicz, Silvia Maria Suter Correia Cadena, Frédéric Bost, Jacques Pouysségur, Nathalie M. Mazure
Publikováno v:
Cellular & Molecular Biology Letters, Vol 24, Iss 1, Pp 1-11 (2019)
Abstract Background Polysaccharides from various sources have been used in traditional medicine for centuries. The beneficial pharmacological effects of plant-derived polysaccharides include anti-tumor activity. Methods Here, we evaluated the anti-ca
Externí odkaz:
https://doaj.org/article/b47fc2e2408e49d9992a5dfabbd2008d
Publikováno v:
Bulletin du Cancer. 110:412-423
Autor:
Marie-Bérengère Troadec, Françoise Porteu, Marie-Laure Arcangeli, Adlen Foudi, Dominique Bluteau, Paulo De Sepulveda, Christel Guillouf, Nathalie M. Mazure, Fabienne Meggetto, Philippe Brunet De La Grange, Cyril Broccardo
Publikováno v:
Bulletin du Cancer. 110:331-335