Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nathalie Langlade"'
Autor:
Mahesh J. Sanganee, Nathalie Langlade, Matthew Whiting, Mike Loft, Steve Shanahan, Sandra Jane Harling, Karim Herbal, Guillaume Bret, John Bryce Strachan, Alan Negus, Peter G. Turner
Publikováno v:
Organic Process Research & Development. 15:112-122
A new route to an H1−H3 antagonist was developed to address scalability and environmental and cost of goods issues associated with the initial route.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d306c8b13a705fdf4d4c55ce3378fe
https://doi.org/10.1021/op1002598
https://doi.org/10.1021/op1002598
Autor:
Nathalie Langlade, John M. Northall, Alastair J. Roberts, Jonathan P. Graham, Andrew J. Whitehead
Publikováno v:
Organic Process Research & Development. 15:44-48
An efficient and scalable synthesis of a glycine transporter inhibitor is presented. The key steps in the synthetic sequence are the formation of a spirocyclic imidazolidinone from an α-amino nitrile and a cyclic ketone and an arylation of 4-methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c3632936aef3455f590a75266bc337
https://doi.org/10.1021/op100210s
https://doi.org/10.1021/op100210s