Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Nathalie L. Albert"'
Autor:
Jonathan Weller, Marcus Unterrainer, Markéta Sonderer, Sophie Katzendobler, Adrien Holzgreve, Annamaria Biczok, Patrick N. Harter, Joerg-Christian Tonn, Nathalie L. Albert, Bogdana Suchorska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Brain tumor volumes as assessed by magnetic resonance imaging (MRI) do not always spatially overlap with biological tumor volumes (BTV) measured by [18F]Fluoroethyltyrosine positron emission tomography ([18F]FET PET). We prospectively invest
Externí odkaz:
https://doaj.org/article/fa7a1d304ca84f3e83fe9bf5f41fbe1a
Autor:
Artem Zatcepin, Johannes Gnörich, Boris-Stephan Rauchmann, Laura M. Bartos, Stephan Wagner, Nicolai Franzmeier, Maura Malpetti, Xianyuan Xiang, Yuan Shi, Samira Parhizkar, Maximilian Grosch, Karin Wind-Mark, Sebastian T. Kunte, Leonie Beyer, Carolin Meyer, Desirée Brösamle, Ann-Christin Wendeln, Collins Osei-Sarpong, Steffanie Heindl, Arthur Liesz, Sophia Stoecklein, Gloria Biechele, Anika Finze, Florian Eckenweber, Simon Lindner, Axel Rominger, Peter Bartenstein, Michael Willem, Sabina Tahirovic, Jochen Herms, Katharina Buerger, Mikael Simons, Christian Haass, Rainer Rupprecht, Markus J. Riemenschneider, Nathalie L. Albert, Marc Beyer, Jonas J. Neher, Lars Paeger, Johannes Levin, Günter U. Höglinger, Robert Perneczky, Sibylle I. Ziegler, Matthias Brendel
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-25 (2024)
Abstract Background Microglial activation is one hallmark of Alzheimer disease (AD) neuropathology but the impact of the regional interplay of microglia cells in the brain is poorly understood. We hypothesized that microglial activation is regionally
Externí odkaz:
https://doaj.org/article/a5bbc5a0c7914c46ad9ff511752e6937
Autor:
Sebastian H. Maier, Stephan Schönecker, Vasiliki Anagnostatou, Sylvia Garny, Alexander Nitschmann, Daniel F. Fleischmann, Marcel Büttner, David Kaul, Detlef Imhoff, Emmanouil Fokas, Clemens Seidel, Peter Hau, Oliver Kölbl, Ilinca Popp, Anca-Ligia Grosu, Jan Haussmann, Wilfried Budach, Eren Celik, Klaus-Henning Kahl, Elgin Hoffmann, Ghazaleh Tabatabai, Frank Paulsen, Adrien Holzgreve, Nathalie L. Albert, Ulrich Mansmann, Stefanie Corradini, Claus Belka, Maximilian Niyazi, Raphael Bodensohn
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 47, Iss , Pp 100790- (2024)
Background: The PRIDE trial (NOA-28; ARO-2024-01; AG-NRO-06; NCT05871021) is designed to determine whether a dose escalation with 75.0 Gy in 30 fractions can enhance the median overall survival (OS) in patients with methylguanine methyltransferase (M
Externí odkaz:
https://doaj.org/article/e593b5076b1b4d3582a15845aa79e307
Autor:
Gloria Biechele, Boris-Stephan Rauchmann, Daniel Janowitz, Katharina Buerger, Nicolai Franzmeier, Endy Weidinger, Selim Guersel, Sebastian Schuster, Anika Finze, Stefanie Harris, Simon Lindner, Nathalie L. Albert, Christian Wetzel, Rainer Rupprecht, Axel Rominger, Carla Palleis, Sabrina Katzdobler, Lena Burow, Carolin Kurz, Mirlind Zaganjori, Lena-Katharina Trappmann, Oliver Goldhardt, Timo Grimmer, Jan Haeckert, Daniel Keeser, Sophia Stoecklein, Estrella Morenas-Rodriguez, Peter Bartenstein, Johannes Levin, Günter U. Höglinger, Mikael Simons, Robert Perneczky, Matthias Brendel
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background and objectives 18-kDa translocator protein position-emission-tomography (TSPO-PET) imaging emerged for in vivo assessment of neuroinflammation in Alzheimer’s disease (AD) research. Sex and obesity effects on TSPO-PET binding hav
Externí odkaz:
https://doaj.org/article/1204a7a1ca6b4f63bf9f3e18c9bf5978
Autor:
Raphael Bodensohn, Daniel F. Fleischmann, Sebastian H. Maier, Vasiliki Anagnostatou, Sylvia Garny, Alexander Nitschmann, Marcel Büttner, Johannes Mücke, Stephan Schönecker, Kristian Unger, Elgin Hoffmann, Frank Paulsen, Daniela Thorwarth, Adrien Holzgreve, Nathalie L. Albert, Stefanie Corradini, Ghazaleh Tabatabai, Claus Belka, Maximilian Niyazi
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 45, Iss , Pp 100706- (2024)
Background and purpose: The PRIDE trial (NOA-28; ARO-2022-12; NCT05871021) is scheduled to start recruitment in October 2023. Its primary objective is to enhance median overall survival (OS), compared to historical median OS rates, in patients with m
Externí odkaz:
https://doaj.org/article/2e39a454d584431f845c26def0ecbd15
Autor:
Lorraine Weidner, Julia Lorenz, Stefanie Quach, Frank K. Braun, Tanja Rothhammer-Hampl, Laura-Marie Ammer, Arabel Vollmann-Zwerenz, Laura M. Bartos, Franziska J. Dekorsy, Adrien Holzgreve, Sabrina V. Kirchleitner, Niklas Thon, Tobias Greve, Viktoria Ruf, Jochen Herms, Stefanie Bader, Vladimir M. Milenkovic, Louisa von Baumgarten, Ayse N. Menevse, Abir Hussein, Julian Sax, Christian H. Wetzel, Rainer Rupprecht, Martin Proescholdt, Nils O. Schmidt, Philipp Beckhove, Peter Hau, Joerg-Christian Tonn, Peter Bartenstein, Matthias Brendel, Nathalie L. Albert, Markus J. Riemenschneider
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of brain tumors. However, due to the heterogeneity of cell populations that contribute to the TSPO-PET signal, imaging interpretation may be challenging.
Externí odkaz:
https://doaj.org/article/882098c23867491bad20bb37d6a6accc
Autor:
Ayse N. Menevse, Laura-Marie Ammer, Arabel Vollmann-Zwerenz, Marcell Kupczyk, Julia Lorenz, Lorraine Weidner, Abir Hussein, Julian Sax, Jasmin Mühlbauer, Nicole Heuschneider, Celine Rohrmus, Laura S. Mai, Birgit Jachnik, Slava Stamova, Valentina Volpin, Franziska C. Durst, Antonio Sorrentino, Maria Xydia, Vladimir M. Milenkovic, Stefanie Bader, Frank K. Braun, Christian Wetzel, Nathalie L. Albert, Joerg-Christian Tonn, Peter Bartenstein, Martin Proescholdt, Nils O. Schmidt, Ralf A. Linker, Markus J. Riemenschneider, Philipp Beckhove, Peter Hau
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Glioblastoma (GB) IDH-wildtype is the most malignant primary brain tumor. It is particularly resistant to current immunotherapies. Translocator protein 18 kDa (TSPO) is upregulated in GB and correlates with malignancy and poor prognosis, but
Externí odkaz:
https://doaj.org/article/5b085ac5cc8b49e9922c86d6fca1cd96
Autor:
Anna Ballweg, Carolin Klaus, Letizia Vogler, Sabrina Katzdobler, Karin Wind, Artem Zatcepin, Sibylle I. Ziegler, Birkan Secgin, Florian Eckenweber, Bernd Bohr, Alexander Bernhardt, Urban Fietzek, Boris-Stephan Rauchmann, Sophia Stoecklein, Stefanie Quach, Leonie Beyer, Maximilian Scheifele, Marcel Simmet, Emanuel Joseph, Simon Lindner, Isabella Berg, Norman Koglin, Andre Mueller, Andrew W. Stephens, Peter Bartenstein, Joerg C. Tonn, Nathalie L. Albert, Tania Kümpfel, Martin Kerschensteiner, Robert Perneczky, Johannes Levin, Lars Paeger, Jochen Herms, Matthias Brendel
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Objectives Reactive gliosis is a common pathological hallmark of CNS pathology resulting from neurodegeneration and neuroinflammation. In this study we investigate the capability of a novel monoamine oxidase B (MAO-B) PET ligand to monitor r
Externí odkaz:
https://doaj.org/article/497126e6fe484a14b58f292c7979ad26
Autor:
Johannes Gnörich, Anika Reifschneider, Karin Wind, Artem Zatcepin, Sebastian T. Kunte, Philipp Beumers, Laura M. Bartos, Thomas Wiedemann, Maximilian Grosch, Xianyuan Xiang, Maryam K. Fard, Francois Ruch, Georg Werner, Mara Koehler, Luna Slemann, Selina Hummel, Nils Briel, Tanja Blume, Yuan Shi, Gloria Biechele, Leonie Beyer, Florian Eckenweber, Maximilian Scheifele, Peter Bartenstein, Nathalie L. Albert, Jochen Herms, Sabina Tahirovic, Christian Haass, Anja Capell, Sibylle Ziegler, Matthias Brendel
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Highlights Microglial activation influences metabolic connectivity. Microglial depletion results in distinct decreases of metabolic connectivity. Metabolic connectivity increases in progranulin deficient mice. Cellular FDG allocation in progranulin d
Externí odkaz:
https://doaj.org/article/f789df68cf5a424e8eef5f896ae436b3
Autor:
Lukas Gold, Enio Barci, Matthias Brendel, Michael Orth, Jiying Cheng, Sabrina V. Kirchleitner, Laura M. Bartos, Dennis Pötter, Maximilian A. Kirchner, Lena M. Unterrainer, Lena Kaiser, Sibylle Ziegler, Lorraine Weidner, Markus J. Riemenschneider, Marcus Unterrainer, Claus Belka, Joerg-Christian Tonn, Peter Bartenstein, Maximilian Niyazi, Louisa von Baumgarten, Roland E. Kälin, Rainer Glass, Kirsten Lauber, Nathalie L. Albert, Adrien Holzgreve
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 188 (2024)
Background: The translocator protein (TSPO) has been proven to have great potential as a target for the positron emission tomography (PET) imaging of glioblastoma. However, there is an ongoing debate about the potential various sources of the TSPO PE
Externí odkaz:
https://doaj.org/article/bab7c24b04b64509ad8004cad24a8c44