Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Nathalie K, Zgheib"'
Autor:
Racha Ghoussaini, Hani Tamim, Martine Elbejjani, Maha Makki, Lara Nasreddine, Hussain Ismaeel, Mona P. Nasrallah, Nathalie K. Zgheib
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
AimRelative telomere length (RTL) predicts the development of many age-related diseases. Yet, few studies have evaluated their longitudinal effect on RTL. We investigated longitudinally the association between cardiometabolic risk factors and RTL.Met
Externí odkaz:
https://doaj.org/article/6ea4b71dc7d34ee385fdf7ac4e0818d0
Publikováno v:
Cancer Medicine, Vol 10, Iss 8, Pp 2877-2884 (2021)
ABSTRACT Background Screening for lung cancer with low‐dose computed tomography (LDCT) was shown to reduce lung cancer incidence and overall mortality, and it has been recently included in international guidelines. Despite the rising burden of lung
Externí odkaz:
https://doaj.org/article/47289701e0e0422ca3f1fff72a6f30c6
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Individuals infected with the COVID-19 virus present with different symptoms of varying severity. In addition, not all individuals are infected despite exposure. Risk factors such as age, sex, and comorbidities play a major role in this v
Externí odkaz:
https://doaj.org/article/fbc3ec5dcc6541488279b7987a2f568a
Autor:
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E. Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie K. Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker M. Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B. Brauch, Balram Chowbay, Werner Schroth
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:712-723
The therapeutic efficacy of tamoxifen is predominantly mediated by its active metabolites 4-hydroxy-tamoxifen and endoxifen, whose formation is catalyzed by the polymorphic cytochrome P450 2D6 (CYP2D6). Yet, known CYP2D6 polymorphisms only partially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e485fec86ec28cdcbd5e4edde802cb62
https://doi.org/10.1002/cpt.2846
https://doi.org/10.1002/cpt.2846
Publikováno v:
Journal of Medical Education and Curricular Development, Vol 7 (2020)
Objective: The American University of Beirut Faculty of Medicine follows the American model of medical education. In 2013-2014, a carefully designed new curriculum replaced the previous, largely traditional curriculum, and aimed to improve student we
Externí odkaz:
https://doaj.org/article/5d4348802f864e3fa7faa80b6a405260
Autor:
Nathalie K. Zgheib, George P. Patrinos
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/8f32ad18f97340338220f3e99eea6b8a
Autor:
Borhan Moradveisi, Samar Muwakkit, Fatemeh Zamani, Ebrahim Ghaderi, Ebrahim Mohammadi, Nathalie K. Zgheib
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer seen in children worldwide and in the Middle East. Although there have been major advances in treatment approaches for childhood ALL, serious toxicities do occur but with signif
Externí odkaz:
https://doaj.org/article/8862f138964f4efd89cee518db9d2ac2
Autor:
Raya Saab, Nathalie K. Zgheib, Samar Muwakkit, Habib El-Khoury, Maya Basbous, Dimitri Maamari
Publikováno v:
Personalized Medicine. 18:431-439
Aim: To evaluate the association between candidate genetic polymorphisms and glucocorticoid-induced osteonecrosis in Arab children treated for acute lymphoblastic leukemia. Methods: A total of 189 children treated for acute lymphoblastic leukemia wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3bb45170931621e9633155367f2a5b
https://doi.org/10.2217/pme-2020-0167
https://doi.org/10.2217/pme-2020-0167
Publikováno v:
The Asia Pacific Scholar, Vol 6, Iss 3, Pp 45-55 (2021)
Introduction: The forced transition to online learning due to the COVID-19 pandemic has impacted medical education significantly. Methods: In this paper, the authors compare the performance of Year 1 and 2 classes of medical students who took the sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26aa3dd47600c13d8011abea3a812c0c
https://doi.org/10.29060/taps.2021-6-3/oa2377
https://doi.org/10.29060/taps.2021-6-3/oa2377
Autor:
Werner Schroth, Stefan Winter, Thomas Mürdter, Elke Schaeffeler, Diana Eccles, Bryony Eccles, Balram Chowbay, Chiea C. Khor, Arafat Tfayli, Nathalie K. Zgheib, Michel Eichelbaum, Matthias Schwab, Hiltrud Brauch
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Purpose: Prediction of impaired tamoxifen (TAM) to endoxifen metabolism may be relevant to improve breast cancer treatment, e.g., via TAM dose increase. The polymorphic cytochrome P450 2D6 (CYP2D6) strongly determines an individual’s capacity for e
Externí odkaz:
https://doaj.org/article/88e85bdd41744421ab1879bce1e36e3e