Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nathalie J van Orsouw"'
Autor:
René C J Hogers, Marjo de Ruiter, Koen H J Huvenaars, Hein van der Poel, Antoine Janssen, Michiel J T van Eijk, Nathalie J van Orsouw
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205577 (2018)
In plant breeding the use of molecular markers has resulted in tremendous improvement of the speed with which new crop varieties are introduced into the market. Single Nucleotide Polymorphism (SNP) genotyping is routinely used for association studies
Externí odkaz:
https://doaj.org/article/91ab404ff9fb40d0a8d89a6d4c14806b
Sequence-based genotyping for marker discovery and co-dominant scoring in germplasm and populations.
Autor:
Hoa T Truong, A Marcos Ramos, Feyruz Yalcin, Marjo de Ruiter, Hein J A van der Poel, Koen H J Huvenaars, René C J Hogers, Leonora J G van Enckevort, Antoine Janssen, Nathalie J van Orsouw, Michiel J T van Eijk
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37565 (2012)
Conventional marker-based genotyping platforms are widely available, but not without their limitations. In this context, we developed Sequence-Based Genotyping (SBG), a technology for simultaneous marker discovery and co-dominant scoring, using next-
Externí odkaz:
https://doaj.org/article/82ba998d5b8d41808173c5600968d3fa
Autor:
Diana Rigola, Jan van Oeveren, Antoine Janssen, Anita Bonné, Harrie Schneiders, Hein J A van der Poel, Nathalie J van Orsouw, René C J Hogers, Michiel T J de Both, Michiel J T van Eijk
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4761 (2009)
Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of
Externí odkaz:
https://doaj.org/article/d7c4c55b1ad449faa3b20e19dec3fdb5
Autor:
Nathalie J van Orsouw, René C J Hogers, Antoine Janssen, Feyruz Yalcin, Sandor Snoeijers, Esther Verstege, Harrie Schneiders, Hein van der Poel, Jan van Oeveren, Harold Verstegen, Michiel J T van Eijk
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1172 (2007)
Application of single nucleotide polymorphisms (SNPs) is revolutionizing human bio-medical research. However, discovery of polymorphisms in low polymorphic species is still a challenging and costly endeavor, despite widespread availability of Sanger
Externí odkaz:
https://doaj.org/article/ce5ebeb87a164af696cce0f36bcb9fe2
Autor:
Michael Josephus Theresia Van Eijk, Nathalie J. van Orsouw, Hein J. A. van der Poel, Antoine Janssen, Koen H. J. Huvenaars, René Cornelis Josephus Hogers, Marjo de Ruiter
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205577 (2018)
PLoS ONE
PLoS ONE
In plant breeding the use of molecular markers has resulted in tremendous improvement of the speed with which new crop varieties are introduced into the market. Single Nucleotide Polymorphism (SNP) genotyping is routinely used for association studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb68f94e4c816224a2a1bd4edf32c1c
http://europepmc.org/articles/PMC6185863?pdf=render
http://europepmc.org/articles/PMC6185863?pdf=render
Publikováno v:
Annals of the New York Academy of Sciences. 928:85-96
With the ample gene sequence information that has become available with the human genome project virtually completed, it has become possible to identify functional gene variants and their frequencies in elderly populations with different aging-relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644c844a9a45657f6faae4f9b438d4cf
https://doi.org/10.1111/j.1749-6632.2001.tb05639.x
https://doi.org/10.1111/j.1749-6632.2001.tb05639.x
Autor:
Hoda Anton-Culver, Frederick P. Li, Regina M. Santella, Irene L. Andrulis, Alice S. Whittemore, Jan Vijg, Saundra S. Buys, Nathalie J. Van Orsouw, Betsy Bove, Jeff Boyd, Melissa C. Southey, Hilmi Ozcelik, John L. Hopper, David Peel, Jeanne C. Beck, Andrew K. Godwin, Deon J. Venter, Susan L. Neuhausen
Publikováno v:
Human Mutation. 20:65-73
A number of methods are used for mutational analysis of BRCA1, a large multi-exon gene. A comparison was made of five methods to detect mutations generating premature stop codons that are predicted to result in synthesis of a truncated protein in BRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d9848ddc29ea08716e2b663bdbe36d
https://doi.org/10.1002/humu.10097
https://doi.org/10.1002/humu.10097
Autor:
Yousin Suh, Marco Calavetta, Jan Vijg, Loyda Torres, Charles B. Scott, David Rines, Nathalie J. Van Orsouw, Mangkey Bounpheng, Sean B. McGrath
Publikováno v:
Genomics. 78:83-90
Two-dimensional gene scanning (TDGS) is a method for analyzing multiple DNA fragments in parallel for all possible sequence variations, using extensive multiplex PCR and two-dimensional electrophoretic separation on the basis of size and melting temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c050572a3a6e1766a3ec574fb59bab8b
https://doi.org/10.1006/geno.2001.6649
https://doi.org/10.1006/geno.2001.6649
Autor:
Nathalie J. Van Orsouw, Charis Eng, George L. Mutter, Patricia L. M. Dahia, Jan Vijg, Kathryn L. Lunetta, Jen Jen Yeh, Francis D. Moore
Publikováno v:
Oncogene. 19:2060-2066
Somatic mutations in mtDNA have recently been identified in colorectal tumours. Studies of oncocytic tumours have led to hypotheses which propose that defects in oxidative phosphorylation may result in a compensatory increase in mitochondrial replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce58765b4c0f9e67a34fdea3dd55b8c3
https://doi.org/10.1038/sj.onc.1203537
https://doi.org/10.1038/sj.onc.1203537
Autor:
Jan Vijg, Frederick P. Li, Youssef Elhaji, Steven A. Narod, Charis Eng, Rahul K. Dhanda, Nathalie J. Van Orsouw
Publikováno v:
Scopus-Elsevier
The hereditary breast and ovarian cancer syndrome is associated with a high frequency of BRCA1 mutations. However, the widespread use of BRCA1 testing has been limited to date by three principal concerns: the fear of loss of health and life insurance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7d048e8f969a6ab0f4aadb661b3a5c
https://doi.org/10.1136/jmg.36.10.747
https://doi.org/10.1136/jmg.36.10.747