Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nathalie H. Gendron"'
Publikováno v:
Neurological Research. 29:413-424
Spinal muscular atrophy (SMA) is caused by survival of motor neuron (SMN) deficiency, leading to specific motor neuron attrition. The time course and molecular pathophysiologic etiology of motor neuron loss observed in SMA remains obscure. Mice heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4655541d9beb528602400fe833f10e7e
https://doi.org/10.1179/016164107x159243
https://doi.org/10.1179/016164107x159243
Autor:
Alex MacKenzie, Nathalie H. Gendron, Anne Johnston, Raouf Fetni, Johannes K. X. Maier, Dita M. Rasper, Zahia Lahoua, Donald W. Nicholson, Ruth S. Slack, Jamshid Davoodi, Sophie Roy
Publikováno v:
The Journal of Neuroscience. 22:2035-2043
The neuronal apoptosis inhibitory protein (NAIP) was identified as a candidate gene for the inherited neurodegenerative disorder spinal muscular atrophy. NAIP is the founding member of a human protein family that is characterized by highly conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce486038ea74c82d17d23bdbd486076
https://doi.org/10.1523/jneurosci.22-06-02035.2002
https://doi.org/10.1523/jneurosci.22-06-02035.2002
Publikováno v:
Proteomics. 7(13)
Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked condition shown to be the result of deletions of the glypican-3 (GPC3) gene. GPC3 is a proteoglycan localized to the cell membrane via a glycosylphosphatidyl-inositol (GPI) anchor. To further eluci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0636e82a5d6965c6168045e4a6380aef
https://pubmed.ncbi.nlm.nih.gov/17549790
https://pubmed.ncbi.nlm.nih.gov/17549790
Autor:
Nathalie H. Gendron, Alex MacKenzie, Sylvia Balabanian, Cynthia R. Coffill, Douglas J. Franks, Alexandra Stewart, Louise Pelletier, Johannes K. X. Maier
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 55(9)
The neuronal apoptosis inhibitory protein (NAIP) gene, also known as the baculovirus inhibitor of apoptosis repeat-containing protein 1 (BIRC1) gene, is a member of the inhibitors of apoptosis (IAP) family and was first characterized as a candidate g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234c629df31bd54abbdb81f4338e2358
https://pubmed.ncbi.nlm.nih.gov/17510375
https://pubmed.ncbi.nlm.nih.gov/17510375
Autor:
Phillip Griffin, Nathalie H. Gendron, Rachel E. Shaye, Isabelle Gaboury, Sarah Kawesa, Zul Merali, Alex MacKenzie, Angelo Mikrogianakis, Julia Lockwood, James S. Hutchison
Publikováno v:
Journal of neurotrauma. 24(2)
Hypoxia worsens brain injury following trauma, but the mechanisms remain unclear. The purpose of this study was to determine the effect of traumatic brain injury (TBI) and secondary hypoxia (9% oxygen) on apoptosis-related protein expression, cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32172da293ae4844dab06bf6016b7bbd
https://pubmed.ncbi.nlm.nih.gov/17375998
https://pubmed.ncbi.nlm.nih.gov/17375998
Autor:
Alex MacKenzie, Nathalie H. Gendron, Aaron Jeffs, Paul Goodyer, Alison Dziarmaga, Michael R. Eccles, Nancy Hache, Diana M. Iglesias, Pierre-Alain Hueber
Publikováno v:
American journal of physiology. Renal physiology. 291(4)
During fetal kidney development, the extent of ureteric bud (UB) branching will determine final nephron endowment for life. Nephron number varies widely among normal humans and those who are born at the low end of the nephron number spectrum may be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01721dcb8c196996c42b5c2899ae4104
https://pubmed.ncbi.nlm.nih.gov/16735463
https://pubmed.ncbi.nlm.nih.gov/16735463
Autor:
Christopher C. Wust, Nicole K. Haynes, Sarah C. Jantzi, Ulrich J. Krull, Farhad Gharabaghi, Paul A. E. Piunno, Nathalie H. Gendron, James Watterson, Sandeep Raha, Christopher C. Kotoris, Alex MacKenzie
Publikováno v:
Nucleic acids research. 32(2)
Rapid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6181969501f8018cef5bc5d5bb5b0836
https://pubmed.ncbi.nlm.nih.gov/14742865
https://pubmed.ncbi.nlm.nih.gov/14742865
Autor:
Donna L. Johnston, Alex MacKenzie, David Barnes, Ingrid Rasquinha, George S. Robertson, Henry Fliss, Rachel E. Derrane, Nathalie H. Gendron, James S. Hutchison, John J.‐. Macmanus, William J. King
Publikováno v:
Journal of neurotrauma. 18(12)
Apoptosis of brain cells is triggered by traumatic brain injury (TBI) and is blocked by caspase inhibitors. The neuronal apoptosis inhibitor protein (NAIP), which has been shown to inhibit apoptosis by both caspase-dependant and caspase-independent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8c065550ca76502d1b3fb2c54280de
https://pubmed.ncbi.nlm.nih.gov/11780864
https://pubmed.ncbi.nlm.nih.gov/11780864
Autor:
Alex MacKenzie, Nathalie H. Gendron
Publikováno v:
Current opinion in neurology. 12(2)
Spinal muscular atrophy is an autosomal recessive disease characterized by motor neurone loss, muscle atrophy and weakness. Deletion or mutation of the SMN1 gene reduces intracellular survival motor neurone protein levels causes spinal muscular atrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287fc471511a61949fb4e8d7ca209704
https://pubmed.ncbi.nlm.nih.gov/10226744
https://pubmed.ncbi.nlm.nih.gov/10226744
Autor:
Angelo Mikrogianakis, Rachel E. Shaye, Phillip Griffin, Sarah Kawesa, Julia Lockwood, Nathalie H. Gendron, Isabelle Gaboury, Zul Merali, Alex E. MacKenzie, James S. Hutchison
Publikováno v:
Journal of Neurotrauma; Feb2007, Vol. 24 Issue 2, p338-353, 16p