Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nathalie Guibourt"'
Autor:
Tamara Maes, Cristina Mascaró, David Rotllant, Michele Matteo Pio Lufino, Angels Estiarte, Nathalie Guibourt, Fernando Cavalcanti, Christian Griñan-Ferré, Mercè Pallàs, Roser Nadal, Antonio Armario, Isidro Ferrer, Alberto Ortega, Nuria Valls, Matthew Fyfe, Marc Martinell, Julio César Castro Palomino, Carlos Buesa Arjol
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233468 (2020)
Transcription disequilibria are characteristic of many neurodegenerative diseases. The activity-evoked transcription of immediate early genes (IEGs), important for neuronal plasticity, memory and behavior, is altered in CNS diseases and governed by e
Externí odkaz:
https://doaj.org/article/f203ca35d63f4f55a0c4e2960580662d
Autor:
Daniel H. Wiseman, Julio Cesar Castro-Palomino, Christophe Willekens, Iñigo Tirapu, Alberto Ortega, Cristina Mascaró, Filippo Ciceri, Guido Kurz, Nathalie Guibourt, Marc Martinell, Cihangir Duy, Nuria Valls, Carlos Buesa, Angels Estiarte, Ari Melnick, Tamara Maes, Michele M.P. Lufino, Tim C. P. Somervaille, Alvaro Perdones, Matthew Colin Thor Fyfe, Serena Lunardi
Publikováno v:
Cancer cell. 33(3)
Summary The lysine-specific demethylase KDM1A is a key regulator of stem cell potential in acute myeloid leukemia (AML). ORY-1001 is a highly potent and selective KDM1A inhibitor that induces H3K4me2 accumulation on KDM1A target genes, blast differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf894e7653b94c6547fc85d60ea372c
https://pubmed.ncbi.nlm.nih.gov/29533778
https://pubmed.ncbi.nlm.nih.gov/29533778
Publikováno v:
Free Radical Biology and Medicine. 32:1244-1253
8-Oxo-7,8-dihydroguanine (8-oxoG) is produced abundantly in DNA exposed to free radicals and reactive oxygen species. The biological relevance of 8-oxoG has been unveiled by the study of two mutator genes in Escherichia coli, fpg, and mutY. Both gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd8844d9ac71094f0db4f00fa1d35cf
https://doi.org/10.1016/s0891-5849(02)00822-5
https://doi.org/10.1016/s0891-5849(02)00822-5
Publikováno v:
Free radical biologymedicine. 32(12)
8-Oxo-7,8-dihydroguanine (8-oxoG) is produced abundantly in DNA exposed to free radicals and reactive oxygen species. The biological relevance of 8-oxoG has been unveiled by the study of two mutator genes in Escherichia coli, fpg, and mutY. Both gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca37e4f2e98518bec6ca70c77193a130
https://pubmed.ncbi.nlm.nih.gov/12057762
https://pubmed.ncbi.nlm.nih.gov/12057762
Autor:
Nathalie Guibourt, Serge Boiteux
Publikováno v:
Biochimie. 82(1)
The biological relevance of oxidative DNA damage has been unveiled by the identification of genes such as fpg of E. coli or OGG1 of Saccharomyces cerevisiae. Both Fpg and Ogg1 proteins are DNA glycosylases/AP lyases that excise 7,8-dihydro-8-oxoguani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d191293a38dfefb37b1e9b5ec44be4
https://pubmed.ncbi.nlm.nih.gov/10717388
https://pubmed.ncbi.nlm.nih.gov/10717388
The OGG1 gene of Saccharomyces cerevisiae codes for a DNA glycosylase that excises 7,8-dihydro-8- oxoguanine (8-OxoG) and 2,6-diamino-4-hydroxy-5- N -methylformamidopyrimidine (Fapy) from damaged DNA. In this paper, we have analysed the substrate spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b72faac252e8e23c61e4f96276f1205
https://europepmc.org/articles/PMC146873/
https://europepmc.org/articles/PMC146873/
Publikováno v:
Developmental biology. 153(2)
The fertilization potential in Phallusia mammillata consisted of an initial rapid depolarization. This initial sperm-triggered depolarization was followed by a phase of membrane depolarization which was of either long or short duration, depending on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0578d31b846efe83b4833d6b862b67
https://pubmed.ncbi.nlm.nih.gov/1397680
https://pubmed.ncbi.nlm.nih.gov/1397680
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379:S30-S31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2419098e2f6608a47d03d4cc68c1fc4
https://doi.org/10.1016/s0027-5107(97)82696-6
https://doi.org/10.1016/s0027-5107(97)82696-6
Autor:
Nathalie Guibourt, Salvador Nogués, Roger Esteban, Luisa Moysset, Xavier Serrat, Eric Lalanne
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Plant Methods
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Plant Methods
Dipòsit Digital de la UB
Universidad de Barcelona
Background: TILLING (Targeting Induced Local Lesions IN Genomes) is a reverse genetic method that combines chemical mutagenesis with high-throughput genome-wide screening for point mutation detection in genes of interest. However, this mutation disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d800c7a650856119fa165aaa90dfc0
http://hdl.handle.net/2445/52918
http://hdl.handle.net/2445/52918