Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nathalie Enjolras"'
Autor:
Yesim Dargaud, Anne Lienhart, Maissaa Janbain, Sandra Le Quellec, Nathalie Enjolras, Claude Negrier
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Externí odkaz:
https://doaj.org/article/b91411ae5e824cb7954bd95f3c9ba4e5
Autor:
Yohann Jourdy, Nathalie Enjolras, Sandra Le Quellec, Jean Claude Bordet, Claude Négrier, Christine Vinciguerra, Yesim Dargaud
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188213 (2017)
Recently our group has described a new autosomal dominant bleeding disorder characterized by very high plasma levels of soluble thrombomodulin (TM). The THBD c.1611C>A (p.Cys537X) mutation in heterozygous state was found in the propositus. This mutat
Externí odkaz:
https://doaj.org/article/888690e9679e4166a6454bc9492bc771
Autor:
Cindy A. Leissinger, Jean Claude Bordet, Yesim Dargaud, Radu Bolbos, Nathalie Enjolras, Marie Brevet, Maissa Janbain
Publikováno v:
Journal of Thrombosis and Haemostasis. 18:584-592
Background Hemophilia is characterized by a compromised hemostatic response with delayed development of a clot and the formation of clots that are vulnerable to fibrinolysis. We proposed to study, in vitro and in factor VIII knockout mice (FVIII-KO),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e130375e2c4cb046dd9e33a164917f7
https://doi.org/10.1111/jth.14694
https://doi.org/10.1111/jth.14694
Autor:
Stephanie Desage, Nathalie Enjolras, Lori A. Holle, Sneha Singh, Xavier Delavenne, Alisa S. Wolberg, Arijit Biswas, Yesim Dargaud
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69d10d7e2e8a67b87686e227f6ccade8
https://doi.org/10.2139/ssrn.4293111
https://doi.org/10.2139/ssrn.4293111
Autor:
Sandrine Meunier, Frédéric Sobas, Sandra Le Quellec, Valérie Chamouard, Stéphanie Désage, Nathalie Enjolras, Claude Negrier
Publikováno v:
Haemophilia. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6e5959a12d16cb56ea5d5f64b53181
https://doi.org/10.1111/hae.14199
https://doi.org/10.1111/hae.14199
Autor:
Nathalie Enjolras, Yesim Dargaud, Sandra Le Quellec, Claude Negrier, Eloïse Perot, Jonathan Girard
Publikováno v:
Thrombosis and Haemostasis. 118:2053-2063
Prophylaxis is currently considered the optimal care for severe haemophilia. For patients and their families one of the major difficulties with prophylaxis is the need for frequent venipunctures. The half-life of standard factor IX (FIX) concentrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f10d5a9557cc4a85c2384a71bbbb48
https://doi.org/10.1055/s-0038-1675787
https://doi.org/10.1055/s-0038-1675787
Autor:
Anne Lienhart, Yesim Dargaud, Sandra Le Quellec, Nathalie Enjolras, Claude Negrier, Maissaa Janbain
Publikováno v:
Haematologica. 103:e181-e183
Emicizumab is a recombinant, humanized, bispecific, monoclonal antibody that bridges activated factor IX and factor X to restore the function of deficient factor VIII. Treatment of bleeding in patients with hemophilia and inhibitors involves the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289ee9629eaa21c157deb23afa07e1fd
https://doi.org/10.3324/haematol.2017.185330
https://doi.org/10.3324/haematol.2017.185330
Autor:
Thibaut Marais, Federico Mingozzi, Elena Barbon, Maria-Grazia Biferi, Sandra Le Quellec, Claude Negrier, Amit C. Nathawani, Nathalie Enjolras, Jean-Claude Bordet, Allison P Dane, Yesim Dargaud
Publikováno v:
Thromb Haemost
Thromb Haemost, 2019, 119, pp.1956-1967. ⟨10.1055/s-0039-1697658⟩
Thromb Haemost, 2019, 119, pp.1956-1967. ⟨10.1055/s-0039-1697658⟩
Gene therapy using recombinant adeno-associated virus (AAV) has induced sustained long-term coagulation human factor IX (hFIX) levels in hemophilia B (HB) patients. However, asymptomatic transient liver toxicity was observed at high vector doses, hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377687d168dd27a1d86f0863c65320ca
https://hal.archives-ouvertes.fr/hal-02880804
https://hal.archives-ouvertes.fr/hal-02880804
Autor:
Jenny McIntosh, Nathalie Enjolras, Amit C. Nathwani, Allison P Dane, Claude Negrier, Cecilia Rosales, Sandra Le Quellec
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 25(1)
Introduction: The variety of treatment for haemophilia B (HB) has recently improved with the emergence of both AAV‐based gene therapy and bioengineered human factor IX (hFIX) molecules with prolonged half‐life due to fusion to either albumin (Alb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef8c49fdfd09d557c49eb103a1deb1a
https://pubmed.ncbi.nlm.nih.gov/30520547
https://pubmed.ncbi.nlm.nih.gov/30520547
Autor:
Cindy A. Leissinger, Nathalie Enjolras, Radu Bolbos, Jean-Claude Bordet, Maissaa Janbain, Yesim Dargaud
Publikováno v:
Blood. 132:2490-2490
Introduction Hemophilia is an X linked disorder characterized by an increased tendency to spontaneous bleeding resulting from profound compromise of the hemostatic response with delayed development of a clot and the formation of clots that are vulner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::025a8c3fd98a0e1665bdaeff060bb5e2
https://doi.org/10.1182/blood-2018-99-119407
https://doi.org/10.1182/blood-2018-99-119407