Abigene, a Prospective, Multicentric Study of Abiraterone Acetate Pharmacogenetics in Metastatic Castration-Resistant Prostate Cancer

Autor: Jean-Marc Ferrero, Hakim Mahammedi, Gwenaelle Gravis, Guilhem Roubaud, Philippe Beuzeboc, Remi Largillier, Delphine Borchiellini, Claude Linassier, Nathalie Ebran, Tanguy Pace-Loscos, Marie-Christine Etienne-Grimaldi, Renaud Schiappa, Jocelyn Gal, Gérard Milano

Publikováno v: Pharmaceutics, Vol 15, Iss 2, p 651 (2023)

Abiraterone acetate (AA) is the first-in-class of drugs belonging to the second-generation of agents inhibiting androgen neosynthesis in advanced prostate cancer. A cumulative experience attests that germinal gene polymorphisms may play a role in the

Externí odkaz: https://doaj.org/article/c04920b18f914032b1945806680881d4

Correction to: Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

Autor: Emmanuel Chamorey, Josiane Otto, Gérard Milano, Nathalie Ebran, Sadal Refae, Jocelyn Gal, Delphine Borchiellini, Patrick Brest, Esma Saada-Bouzid, Frederic Peyrade

Publikováno v: Investigational New Drugs. 39:287-292

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40c4e6a724d0d64ed07bbfe65eeeb33b
https://doi.org/10.1007/s10637-020-00954-x

Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics

Autor: Frederic Peyrade, Gérard Milano, Patrick Brest, Jocelyn Gal, Sadal Refae, Joël Guigay, Nathalie Ebran, Delphine Borchiellini, Damien Giacchero, Esma Saada-Bouzid

Publikováno v: Scientific Reports
Scientific Reports, 2020, 10 (1), pp.3565. ⟨10.1038/s41598-020-60437-0⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.3565. ⟨10.1038/s41598-020-60437-0⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)

Hyperprogressive disease (HPD), an unexpected acceleration of tumor growth kinetics, is described in cancer patients treated with anti-PD-1/anti-PD-L1 agents. Here, our aim was to take into consideration the host and explore whether single nucleotide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeeae9d1294ddd54569bd1262bca0d9
http://europepmc.org/articles/PMC7046673

Microsatellite instability associated with durable complete response to PD-L1 inhibitor in head and neck squamous cell carcinoma

Autor: Cécile Badoual, Anne Sudaka-Bahadoran, Alexandre Bozec, Magalie Pascale Tardy, Ilaria Di Mauro, Florence Pedeutour, Sadal Refae, Esma Saada-Bouzid, Nathalie Ebran, Karen Benezery, Joël Guigay, Frederic Peyrade

Publikováno v: Oral Oncology. 80:104-107

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::011d9cd302c19547c789ed4c6eb28013
https://doi.org/10.1016/j.oraloncology.2018.04.001

Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer

Autor: Gérard Milano, Alexandre Bozec, Mathieu Gautier, Hedi Ben Yahia, Nina Radosevic-Robin, Serge Marcie, Emmanuel Chamorey, Frédérique Penault-Llorca, Nathalie Ebran

Publikováno v: Head & Neck. 39:151-159

Background The purpose of this study was to investigate the effects of combining the phosphotidylinositol-3-kinase (PI3K) inhibitor buparlisib (BKM)120 with the anti-epidermal growth factor receptor (EGFR) agent cetuximab and radiotherapy (RT) on an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7f13fba92dc896e457f05807eff26d5
https://doi.org/10.1002/hed.24560