Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Nathalie Desmet"'
Implication of system xc − in neuroinflammation during the onset and maintenance of neuropathic pain
Autor:
Pauline Beckers, Inês Belo Do Nascimento, Mathilde Charlier, Nathalie Desmet, Ann Massie, Emmanuel Hermans
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Despite the high prevalence of neuropathic pain, treating this neurological disease remains challenging, given the limited efficacy and numerous side effects associated with current therapies. The complexity in patient management
Externí odkaz:
https://doaj.org/article/07ad0c44e2804160af35294cd3e47e92
Autor:
Nathalie Desmet
Publikováno v:
Lien Social et Politiques, Iss 91 (2023)
L’expansion des pratiques artistiques sociales et collaboratives depuis les années 1990 place les résidences d’artistes comme des dispositifs particulièrement adaptés à la construction d’une citoyenneté culturelle, notamment dans les zone
Externí odkaz:
https://doaj.org/article/ed255984acd048f3aa11733a50b8153d
Autor:
Tran Dieu Hang, Huynh Minh Hung, Pauline Beckers, Nathalie Desmet, Mohamed Lamrani, Ann Massie, Emmanuel Hermans, Kenno Vanommeslaeghe
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The cystine/glutamate antiporter system xc− (Sxc−) belongs to the SLC7 family of plasma membrane transporters. It exports intracellular glutamate along the latter’s concentration gradient as a driving force for cellular uptake of cystine. Once
Externí odkaz:
https://doaj.org/article/ac14a4a72ef840b786cb0796f3ae9887
Autor:
Inês Belo do Nascimento, Gamze Ates, Nathalie Desmet, Pauline Beckers, Ann Massie, Emmanuel Hermans
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1183 (2023)
Alterations in the activity of the regulator of cell metabolism AMP-activated protein kinase (AMPK) have been reported in motor neurons from patients and animal models of amyotrophic lateral sclerosis (ALS). Considering the key role played by astrocy
Externí odkaz:
https://doaj.org/article/534ea97792394728a8336b60f634aab9
Autor:
Pauline Beckers, Olaya Lara, Ines Belo do Nascimento, Nathalie Desmet, Ann Massie, Emmanuel Hermans
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
Disruption of the glutamatergic homeostasis is commonly observed in neurological diseases and has been frequently correlated with the altered expression and/or function of astrocytic high-affinity glutamate transporters. There is, however, a growing
Externí odkaz:
https://doaj.org/article/3e26255d1138482bbd2b40219b0d57ef
Autor:
Inês Belo do Nascimento, Marie Verfaillie, Gamze Ates, Pauline Beckers, Virginie Joris, Nathalie Desmet, Ann Massie, Emmanuel Hermans
Publikováno v:
Cells, Vol 11, Iss 11, p 1800 (2022)
Energy homeostasis in the central nervous system largely depends on astrocytes, which provide metabolic support and protection to neurons. Astrocytes also ensure the clearance of extracellular glutamate through high-affinity transporters, which indir
Externí odkaz:
https://doaj.org/article/7d291e408996464abd1c4c3feac5a823
Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
Autor:
Pierre J. Doyen, Maxime Vergouts, Amandine Pochet, Nathalie Desmet, Sabien van Neerven, Gary Brook, Emmanuel Hermans
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Regulators of G-protein signaling (RGS) are major physiological modulators of G-protein-coupled receptors (GPCR) signaling. Several GPCRs expressed in both neurons and astrocytes participate in the central control of pain processi
Externí odkaz:
https://doaj.org/article/f7145072bd09415d90e5d91c47590bc2
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97649 (2014)
Dysregulation of the astroglial glutamate transporters GLAST and GLT-1 has been implicated in several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) where a loss of GLT-1 protein expression and activity is reported. Furthe
Externí odkaz:
https://doaj.org/article/8b4c809b31e643ac9943c7da66f9bdf1
Autor:
Pauline, Beckers, Olaya, Lara, Ines, Belo do Nascimento, Nathalie, Desmet, Ann, Massie, Emmanuel, Hermans
Publikováno v:
Frontiers in Cellular Neuroscience
Disruption of the glutamatergic homeostasis is commonly observed in neurological diseases and has been frequently correlated with the altered expression and/or function of astrocytic high-affinity glutamate transporters. There is, however, a growing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8f89ba40ffb07a380b7866397a3c63d
https://pubmed.ncbi.nlm.nih.gov/35095428
https://pubmed.ncbi.nlm.nih.gov/35095428
Autor:
Nathalie Desmet, Pierre J. Doyen, Ronald Deumens, Barbara Bosier, Giulio G. Muccioli, Amandine Brolet, Eman Ahmed, Emmanuel Hermans
Publikováno v:
British Journal of Pharmacology. 172:5333-5346
Background and Purpose Regulators of G protein signalling (RGS) are major determinants of metabotropic receptor activity, reducing the lifespan of the GTP-bound state of G proteins. Because the reduced potency of analgesic agents in neuropathic pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d6ab7140c7cbda37f632fd4d1ed31d
https://doi.org/10.1111/bph.13324
https://doi.org/10.1111/bph.13324