Výsledky vyhledávání - "Nathalie Court"

Akademický článek

Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms.

Autor: Nathalie Court, Stéphanie Rose, Marie-Laure Bourigault, Sophie Front, Olivier R Martin, Jennifer K Dowling, Elaine F Kenny, Luke O'Neill, François Erard, Valerie F J Quesniaux

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24631 (2011)

Mycobacteria develop strategies to evade the host immune system. Among them, mycobacterial LAM or PIMs inhibit the expression of pro-inflammatory cytokines by activated macrophages. Here, using synthetic PIM analogues, we analyzed the mode of action

Externí odkaz: https://doaj.org/article/6af7d97d62e44674902b88aab5c3e670

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A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development

Autor: Yan Li, Hergen Spits, Nathalie Court, Nicolas Legrand, Antoine Toubert, Helene Strick-Marchand, Jean-Jacques Mention, Erwan Corcuff, James P. Di Santo, Guillemette Masse-Ranson

Publikováno v: European journal of immunology, 46(5), 1291-1299. Wiley-VCH Verlag

Humanized mice harboring human immune systems (HIS) represent a platform to study immune responses against pathogens and to screen vaccine candidates and novel immunotherapeutics. Innate and adaptive immune responses are suboptimal in HIS mice, possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc487d417e4e27406627912a17766a9
https://pure.amc.nl/en/publications/a-novel-flt3deficient-his-mouse-model-with-selective-enhancement-of-human-dc-development(090d7e15-0533-46bd-a8cf-3f5826fe2335).html

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Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells

Autor: Nathalie Court, Henry Jay Forman, Hongqiao Zhang

Publikováno v: Redox Report. 12:101-106

4-Hydroxynonenal (HNE), a major electrophilic product of lipid peroxidation, is regarded as both a marker of oxidative stress and a mediator of oxidative damage. At subtoxic concentrations, however, this compound has been shown to be a signalling mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b339f81885d196a6e809f64d75b34047
https://doi.org/10.1179/135100007x162266

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Relative contribution of IL‐1α, IL‐1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG

Autor: Yoichiro Iwakura, Nathalie Court, Marie Laure Bourigault, Marc Le Bert, François Erard, Virginie Vasseur, Rachel Vacher, Bernhard Ryffel, Stéphanie Rose, Irene Garcia, Muazzam Jacobs, Noria Segueni, Valérie F. J. Quesniaux

Publikováno v: Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, John Wiley & Sons Ltd, 2013, 1 (1), pp.47-62. ⟨10.1002/iid3.9⟩
Immunity, Inflammation and Disease, Vol. 1, No 1 (2013) pp. 47-62

International audience; TNF and IL-1 are major mediators involved in severe inflammatory diseases against which therapeutic neutralizing antibodies are developed. However, both TNF and IL-1 receptor pathways are essential for the control of Mycobacte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57aa9e138b7b125c5ac0997a99b1bf98
https://hal.archives-ouvertes.fr/hal-03477918

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Prominent role for T cell-derived tumour necrosis factor for sustained control of Mycobacterium tuberculosis infection

Autor: Nasiema Allie, Cecile Fremond, Muazzam Jacobs, Vladimir Yeremeev, Yuriy V. Shebzukhov, Marie-Laure Bourigault, Sergei I. Grivennikov, Bernhard Ryffel, Sergei A. Nedospasov, Nai-Jen Hsu, Roanne Keeton, Nathalie Court, Valérie F. J. Quesniaux

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2013, 3, pp.1809. ⟨10.1038/srep01809⟩

International audience; Tumour Necrosis Factor (TNF) is critical for host control of M. tuberculosis, but the relative contribution of TNF from innate and adaptive immune responses during tuberculosis infection is unclear. Myeloid versus T-cell-deriv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ab284490ec5e5c65a46d614f934b70
https://pubmed.ncbi.nlm.nih.gov/23657146

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GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands

Autor: Carlos Arterio Sorgi, Daniela Carlos, Fabiani Gai Frantz, Bernhard Ryffel, Patricia A. Assis, Valérie F. J. Quesniaux, Nathalie Court, Lúcia Helena Faccioli, Stéphanie Rose, Francisco Wanderley Garcia Paula-Silva

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40523 (2012)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

In response to pathogen recognition by Toll-like receptors (TLRs) on their cell surface, macrophages release lipid mediators and cytokines that are widely distributed throughout the body and play essential roles in host responses. Granulocyte macroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2684b5ee748659c427dff648557fed14
https://pubmed.ncbi.nlm.nih.gov/22808181

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Phosphatidyl myo-inositol mannosides mimics built on an acyclic or heterocyclic core: synthesis and anti-inflammatory properties

Autor: Stéphanie Rose, Marie-Laure Bourigault, Olivier R. Martin, Bernhard Ryffel, Nathalie Court, François Erard, Valérie F. J. Quesniaux, Sophie Front

Publikováno v: ChemMedChem
ChemMedChem, 2011, 6 (11), pp.2081-93. ⟨10.1002/cmdc.201100291⟩
ChemMedChem, Wiley-VCH Verlag, 2011, 6 (11), pp.2081-93. ⟨10.1002/cmdc.201100291⟩

International audience; Phosphatidyl myo-inositol mannosides (PIMs) are constituents of the mycobacterial cell wall and possess immunomodulatory activities. Certain PIM derivatives have immunoprotective activity and are of interest as anti-inflammato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f570efa57f0e732f6c4f70989d5b9957
https://pubmed.ncbi.nlm.nih.gov/21901834

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Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms

Autor: Marie Laure Bourigault, Stéphanie Rose, Olivier R. Martin, François Erard, Nathalie Court, Elaine F. Kenny, Sophie Front, Luke A. J. O'Neill, Valérie F. J. Quesniaux, Jennifer K. Dowling

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24631 (2011)
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (9), pp.e24631. ⟨10.1371/journal.pone.0024631⟩

International audience; Mycobacteria develop strategies to evade the host immune system. Among them, mycobacterial LAM or PIMs inhibit the expression of pro-inflammatory cytokines by activated macrophages. Here, using synthetic PIM analogues, we anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0db21c03f2977b64398cfd8ee1bd37
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21949737/?tool=EBI

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Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection

Autor: Siamon Gordon, Padraic G. Fallon, Rachel Vacher, Cecile Fremond, Virginie Vasseur, Yury V. Shebzukhov, Nathalie Court, Vladimir Yeremeev, Valérie F. J. Quesniaux, Sergei A. Nedospasov, Isabelle Maillet, Bernhard Ryffel, Hiroshi Suzuki

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2010, 184 (12), pp.7057-70. ⟨10.4049/jimmunol.1000164⟩

Mycobacterium tuberculosis is recognized by multiple pattern recognition receptors involved in innate immune defense, but their direct role in tuberculosis pathogenesis remains unknown. Beyond TLRs, scavenger receptors (SRs) and C-type lectins may pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243891262b6e4859a710ceefa722b13f
https://hal.archives-ouvertes.fr/hal-00591485

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