Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nathalie Charland"'
Autor:
Paulina Kaplonek, Deniz Cizmeci, Jessica Shih-Lu Lee, Sally A. Shin, Stephanie Fischinger, Philipe Gobeil, Stéphane Pillet, Nathalie Charland, Brian J. Ward, Galit Alter
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Despite the success of existing COVID-19 vaccine platforms, the persistent limitations in global deployment of vaccines and waning immunity exhibited by many of the currently deployed vaccine platforms have led to perpetual outbreaks of SARS
Externí odkaz:
https://doaj.org/article/d55dbfe42ce74d4cbb08ac3c06582bd4
Autor:
Nathalie Charland, Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Annie Séguin, Alexander Makarkov, Gretchen Heizer, Kapil Bhutada, Asif Mahmood, Sonia Trépanier, Karen Hager, Julia Jiang-Wright, Judith Atkins, Pooja Saxena, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, François Roman, Robbert Van Der Most, Maria Angeles Ceregido, Marc Dionne, Guy Tellier, Jean-Sébastien Gauthier, Brandon Essink, Michael Libman, Jason Haffizulla, André Fréchette, Marc-André D’Aoust, Nathalie Landry, Brian J. Ward
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract The rapid spread of SARS-CoV-2 continues to impact humanity on a global scale with rising total morbidity and mortality. Despite the development of several effective vaccines, new products are needed to supply ongoing demand and to fight var
Externí odkaz:
https://doaj.org/article/b6a4cc5cfcb64d00803666e2639e3ffb
Autor:
Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Nathalie Charland, Aurélien Lorin, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, Robbert Van Der Most, François Roman, Maria Angeles Ceregido, Nathalie Landry, Marc-André D’Aoust, Brian J. Ward
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Here, the authors report results from a Phase 1 trial with an AS03-adjuvanted, plant-based virus-like particle displaying the spike protein of the ancestral SARS-CoV-2. Six months post-second dose, they observe good neutralizing antibody titers and T
Externí odkaz:
https://doaj.org/article/5f0bb8c08c0147bdb05f3296700f7ce0
Autor:
Lauren Ramjee, William Lemay, Nesrin Vurgun, Nathalie Charland, Chris T. Bauch, Gokul Raj Pullagura, Sherilyn K. D. Houle, Gabriel Tremblay
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 10, Pp 3643-3651 (2021)
Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada. Methods Using Monte Carlo simulations, the number of
Externí odkaz:
https://doaj.org/article/3722c65195d2432c9c502831718b6efc
Autor:
Brian J. Ward, Stephane Pillet, Nathalie Charland, Sonia Trepanier, Julie Couillard, Nathalie Landry
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 3, Pp 647-656 (2018)
The search for a test that can predict vaccine efficacy is an important part of any vaccine development program. Although regulators hesitate to acknowledge any test as a true ‘correlate of protection’, there are many precedents for defining ‘s
Externí odkaz:
https://doaj.org/article/b38b3b67e6ba45d5a11dcc4f50af483b
Autor:
Fernando Alvarez, Roman Istomine, Hilary Hendin, Breanna Hodgins, Stephane Pillet, Jörg H. Fritz, Nathalie Charland, Brian J. Ward, Ciriaco A. Piccirillo
Publikováno v:
ImmunoHorizons. 6:384-397
Inactivated influenza vaccines have struggled to provide consistent protection in older individuals. Circumventing immune senescence, an aging of the immune response characterized by weak humoral responses to vaccines, and unchecked inflammation duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1dec251507a1d2cf669329028f03043
https://doi.org/10.4049/immunohorizons.2200036
https://doi.org/10.4049/immunohorizons.2200036
Autor:
Stéphane Pillet, Prabhu S. Arunachalam, Guadalupe Andreani, Nadia Golden, Jane Fontenot, Pyone Pyone Aye, Katharina Röltgen, Gabrielle Lehmicke, Philipe Gobeil, Charlotte Dubé, Sonia Trépanier, Nathalie Charland, Marc-André D’Aoust, Kasi Russell-Lodrigue, Christopher Monjure, Robert V. Blair, Scott D. Boyd, Rudolf P. Bohm, Jay Rappaport, François Villinger, Nathalie Landry, Bali Pulendran, Brian J. Ward
Publikováno v:
Cellular and Molecular Immunology
Although antivirals are important tools to control severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, effective vaccines are essential to control the current coronavirus disease 2019 (COVID-19) pandemic. Plant-derived virus-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196ab61cd1a7251d30167a864e952c12
https://doi.org/10.1038/s41423-021-00809-2
https://doi.org/10.1038/s41423-021-00809-2
Autor:
Sherilyn K.D. Houle, Nesrin Vurgun, Gokul Raj Pullagura, Gabriel Tremblay, Lauren Ramjee, Nathalie Charland, William Lemay, Chris T. Bauch
Publikováno v:
Human Vaccines & Immunotherapeutics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada. Methods Using Monte Carlo simulations, the number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827a88d417a95ed7baafcea6739d9de3
https://doi.org/10.1080/21645515.2021.1908797
https://doi.org/10.1080/21645515.2021.1908797
Autor:
Karen J, Hager, Gonzalo, Pérez Marc, Philipe, Gobeil, Ricardo S, Diaz, Gretchen, Heizer, Conrado, Llapur, Alexander I, Makarkov, Eduardo, Vasconcellos, Stéphane, Pillet, Fernando, Riera, Pooja, Saxena, Priscila, Geller Wolff, Kapil, Bhutada, Garry, Wallace, Hessam, Aazami, Christine E, Jones, Fernando P, Polack, Luciana, Ferrara, Judith, Atkins, Iohann, Boulay, Jiwanjeet, Dhaliwall, Nathalie, Charland, Manon M J, Couture, Julia, Jiang-Wright, Nathalie, Landry, Sophie, Lapointe, Aurélien, Lorin, Asif, Mahmood, Lawrence H, Moulton, Emmy, Pahmer, Julie, Parent, Annie, Séguin, Luan, Tran, Thomas, Breuer, Maria-Angeles, Ceregido, Marguerite, Koutsoukos, François, Roman, Junya, Namba, Marc-André, D'Aoust, Sonia, Trepanier, Yosuke, Kimura, Brian J, Ward, Steven, Zeig
Publikováno v:
The New England journal of medicine. 386(22)
Backgroud: coronavirus-like particles (CoVLP) that are produced in plants and display the prefusion spike glycoprotein of the original strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are combined with an adjuvant (Adjuvant Syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a353a3d3b32eb6ee2aacee051da324f
https://pubmed.ncbi.nlm.nih.gov/35507476
https://pubmed.ncbi.nlm.nih.gov/35507476
Autor:
Brian J. Ward, Nathalie Charland, Nathalie Landry, Robbert van der Most, Donald C. Vinh, Maria de los Angeles Ceregido Perez, Aurélien Lorin, Matthew P. Cheng, Iohann Boulay, Stéphane Pillet, Marc-André D'Aoust, François Roman, Philipe Gobeil, Philippe Boutet
As the SARS-COV-2 pandemic evolves, what is expected of vaccines extends beyond efficacy to include consideration of both durability and variant cross-reactivity. This report expands on previously reported immunogenicity results from a Phase 1 trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d6b9b57bc834cf8b38f63643ac5f09
https://doi.org/10.1101/2021.08.04.21261507
https://doi.org/10.1101/2021.08.04.21261507
