Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nathalie Beslu"'
Autor:
Janet J. Bijl, Aline Mamo, Alexander Thompson, Nathalie Beslu, Jana Krosl, Simon Girard, Guy Sauvageau, Evert Kroon, Nadine Mayotte, Mark Featherstone, Richard Bisaillon
Publikováno v:
Blood. 108:622-629
The Hoxa9 and Meis1 genes represent important oncogenic collaborators activated in a significant proportion of human leukemias with genetic alterations in the MLL gene. In this study, we show that the transforming property of Meis1 is modulated by 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05380d6a1bcbe3e0e61247a608e2b78d
https://doi.org/10.1182/blood-2005-06-2244
https://doi.org/10.1182/blood-2005-06-2244
Publikováno v:
Blood. 104:2307-2314
HOXB4 overexpression induces unique in vivo and in vitro expansion of hemopoietic stem cells (HSCs) without causing leukemia. Very little is known about the molecular basis underlying HOXB4-induced HSC self-renewal. We now report the in vitro prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f8c9edcefa68af935aff7082e09877
https://doi.org/10.1182/blood-2004-04-1653
https://doi.org/10.1182/blood-2004-04-1653
Publikováno v:
Nature Medicine. 9:1428-1432
Hematopoietic stem cells (HSCs) can self-renew extensively after transplantation. The conditions supporting their in vitro expansion are still being defined. Retroviral overexpression of the human homeobox B4 (HOXB4) gene in mouse bone marrow cells e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4696a7c90eb374d30f8a6c03c781d7
https://doi.org/10.1038/nm951
https://doi.org/10.1038/nm951
Autor:
Mustapha Aoubala, Paulo De Sepulveda, Robert Rottapel, Nathalie Casteran, Sébastien Letard, Nathalie Beslu, Patrice Dubreuil, Eric Lecocq
Publikováno v:
Oncogene. 22:4710-4722
Mutations of KIT receptor tyrosine kinase are found in the majority of patients with mastocytosis and in most gastrointestinal stromal tumors. Oncogenic KIT mutations in GISTs are located in the KIT juxtamembrane domain (JMD), while codon 816 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96ff47ca4d35c06c787ad20abf7ea69
https://doi.org/10.1038/sj.onc.1206587
https://doi.org/10.1038/sj.onc.1206587
Publikováno v:
Immunity. 18(4):561-571
We previously showed that HOXB4 is a potent stimulator of hematopoietic stem cell (HSC) proliferation in vivo and ex vivo. As a result, HOXB4 overexpressing HSCs are 20- to 50-times more competitive than untransduced cells when transplanted into mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1d0b54a1b57a96b081c36fdb6496e9
Autor:
Olivier Rosnet, Hans-Jörg Bühring, Odile deLapeyrière, Nathalie Beslu, Chrystel Lavagna, Sylvie Marchetto, Irene Rappold, Hans.G. Drexler, Françoise Birg, Robert Rottapel, Charles Hannum, Patrice Dubreuil, Daniel Birnbaum
Publikováno v:
ResearcherID
FLT3 is a receptor tyrosine kinase of 130-55 kDa expressed on normal bone marrow stem and early progenitor cells and on leukemic blasts from patients with acute leukemias. The FLT3 ligand, FL, is a new cytokine which acts on hematopoietic progenitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbf328224bc192613a6050864cffd84
https://doi.org/10.1159/000203881
https://doi.org/10.1159/000203881
Autor:
H.T. Hassan, Diana Linnekin, Hisamaru Hirai, Tiziano Barbui, Anna Rita Migliaccio, Jonathan R. Keller, Sarah R. Weiler, Akihiro Iwamatsu, Nathalie Beslu, Stefano Pileri, C. Nissen, Olivier Rosnet, Sante Tura, M. Federico, Masayuki Yamamoto, Vincent Geenen, Sandra N. Catlin, Nader G. Abraham, Shigehiko Imagawa, John E. Wagner, Hans G. Drexler, Candy S. DeBerry, M. Baiocchi, Giuseppe Saglio, Emanuela Moroni, Patrice Dubreuil, Sylvie Marchetto, Lorenzo Leoncini, Ko Sasaki, Alessandra Fortuna, F. Nappi, Abdellah Benhida, Eric Vandersmissen, Hans-Jörg Bühring, Vittorio Rizzoli, Janis L. Abkowitz, Filippo Gherlinzoni, Doraid Jarrar, Douglas K. Ferris, Jean-Pierre Kremer, Hideharu Odai, Elisabeth Spitzer, Ursula Steckholzer, Gianantonio Rosti, Alessandro Rambaldi, A. Filipowicz, Françoise Birg, Miriam Fogli, Béatrice Goxe, Francis W. Ruscetti, Stefania Damiani, Antonino Carbone, Camillo Almici, Jennifer K. Morrow, K. Pugliese, Wolfgang Ertel, B. Speck, Henri Martens, Peter Dörmer, Nedda K. Hughes, Sergio Ottolenghi, Alessandro Gozzetti, Giovanni Migliaccio, Peter Guttorp, Gianluca Gaidano, Yves Vanneste, Charles Hannum, Teresa Lerede, Renato Bassan, A. Tichelli, Ornella Leone, Gisella Volpe, H. Baldomero, Vincent S. Gallicchio, James Gajewski, Annunziata Gloghini, A. Gratwohl, A. Zander, Barbara Giglioni, Yoshio Yazaki, Sergio Giralt, Guiseppe Visani, Lucia Catani, Kam-Fai Tse, Roberto M. Lemoli, Eishi Ashihara, Robert Rottapel, Imane Achour, Richard E. Champlin, C. Chelucci, Elena Sabattini, L. John, P. D’Aloja, Yasusada Miura, Claudio Ceccarelli, Monica T. Persik, Robert A.J. Oostendorp, P. Verani, Daniel Birnbaum, Ouafae Kecha, Dan L. Longo, Brunangelo Falini, Donatella Santini, Paolo Ghia, R. Bona, Carmelo Carlo-Stella, Yutaka Hanazono, Chrystel Lavagna, Irene Rappold, Sherry Mou, Cristina Pastore, F. Mavilio, Odile deLapeyrière
Publikováno v:
Acta Haematologica. 95:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd2255bc7f3b9af0090d0535ad2d1346
https://doi.org/10.1159/000203866
https://doi.org/10.1159/000203866
Autor:
Sarit Assouline, Abdellatif Amri, Denis-Claude Roy, Biljana Culjkovic, Nathalie Beslu, Caroline Rousseau, Stephen Caplan, Katherine L. B. Borden, Eftihia Cocolakis, Wilson H. Miller, Brian Leber
Publikováno v:
Blood. 114(2)
The eukaryotic translation initiation factor eIF4E is elevated in 30% of malignancies including M4/M5 subtypes of acute myeloid leukemia (AML). The oncogenic potential of eIF4E arises from its ability to bind the 7-methyl guanosine (m7G) cap on mRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0564db773f7cc18695f125e73bff9dfd
https://pubmed.ncbi.nlm.nih.gov/19433856
https://pubmed.ncbi.nlm.nih.gov/19433856
Publikováno v:
Immunity. 18(4)
We previously showed that HOXB4 is a potent stimulator of hematopoietic stem cell (HSC) proliferation in vivo and ex vivo. As a result, HOXB4 overexpressing HSCs are 20- to 50-times more competitive than untransduced cells when transplanted into mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b036764301bdc0a2d0659fa7461b8dbc
https://pubmed.ncbi.nlm.nih.gov/12705858
https://pubmed.ncbi.nlm.nih.gov/12705858
Autor:
David Jérémie Birnbaum, Olivier Rosnet, Nathalie Beslu, Aurran-Schleinitz T, Sylvie Marchetto, Jean-Paul Borg, Emmanuel Fournier, Patrice Dubreuil
Publikováno v:
Leukemia. 13(9)
The FLT3 receptor tyrosine kinase and its ligand, FL, regulate the development of hematopoietic stem cells and early B lymphoid progenitors. FL has a strong capacity to boost production of dendritic and natural killer cells in vivo, thereby providing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ad4bdc0287f6a8e098311cb614d114
https://pubmed.ncbi.nlm.nih.gov/10482988
https://pubmed.ncbi.nlm.nih.gov/10482988