Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nathalie Berube"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Increasing the number of CpG dinucleotides in RNA viral genomes, while preserving the original amino acid composition, leads to impaired infection which does not cause disease. Beneficially, impaired infection evokes antiviral host immune responses p
Externí odkaz:
https://doaj.org/article/2bdfc318cd4841d6b725eced963cbaae
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1098-1107 (2019)
ABSTRACTStudies in mice showed that African Zika virus (ZIKV) strains cause more damage in embryos. These studies, however, were limited to the mouse-adapted African MR766 strain or infection at early gestation. Here, we compared infection of Asian a
Externí odkaz:
https://doaj.org/article/de203b968a724a908af183e2e3929fe0
Autor:
Ivan Trus, Daniel Udenze, Nathalie Berube, Colette Wheler, Marie-Jocelyne Martel, Volker Gerdts, Uladzimir Karniychuk
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Experimental increase of CpG dinucleotides in an RNA virus genome impairs infection providing a promising approach for vaccine development. While CpG recoding is an emerging and promising vaccine approach, little is known about infection phenotypes c
Externí odkaz:
https://doaj.org/article/316895b5c1504667972404afd82bee00
Autor:
Ivan Trus, Daniel Udenze, Brian Cox, Nathalie Berube, Rebecca E Nordquist, Franz Josef van der Staay, Yanyun Huang, Gary Kobinger, David Safronetz, Volker Gerdts, Uladzimir Karniychuk
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1008038 (2019)
Zika virus (ZIKV) infection during human pregnancy may lead to severe fetal pathology and debilitating impairments in offspring. However, the majority of infections are subclinical and not associated with evident birth defects. Potentially detrimenta
Externí odkaz:
https://doaj.org/article/2670f2c96c49436889c52c21e2d316a0
Publikováno v:
Viruses, Vol 13, Iss 9, p 1827 (2021)
The host’s immune status may affect virus evolution. Little is known about how developing fetal and placental immune milieus affect virus heterogeneity. This knowledge will help us better understand intra-host virus evolution and how new virus vari
Externí odkaz:
https://doaj.org/article/95bfaf5e22ab4e31ac15e2e0d72c3a09
Publikováno v:
Viruses, Vol 12, Iss 5, p 579 (2020)
We studied whether cytosine phosphate–guanine (CpG) recoding in a viral genome may provide oncolytic candidates with reduced infection kinetics in nonmalignant brain cells, but with high virulence in glioblastoma stem cells (GSCs). As a model, we u
Externí odkaz:
https://doaj.org/article/57462ec0178146738e14eac7e5434e5b
Time and temperature requirements for improved heat killing of pathogens in swine transport trailers
Autor:
Shirley Hauta, Nathalie Berube, Hans Deason, Terry Fonstad, Stacey Strom, Elaine Vanmoorlehem, Volker Gerdts, Janet E. Hill, Jill van Kessel, Champika Fernando
Publikováno v:
2020 ASABE Annual International Virtual Meeting, July 13-15, 2020.
Autor:
Pooja Choudhary, Amir Khajavinia, Ramin Mohammadi, Siew Hon Ng, Nathalie Bérubé, Damayanthi Yalamati, Azita Haddadi, Heather L. Wilson
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
An effective single-dose vaccine that protects the dam and her suckling offspring against infectious disease would be widely beneficial to livestock animals. We assessed whether a single-dose intramuscular (i.m.) porcine epidemic diarrhea virus (PEDV
Externí odkaz:
https://doaj.org/article/45fdc4acf18b4a97b9d17cf395f7c0bd
Autor:
Yan Yang, Connie L Mahaffey, Nathalie Bérubé, Terry P Maddatu, Gregory A Cox, Wayne N Frankel
Publikováno v:
PLoS Genetics, Vol 3, Iss 7, p e124 (2007)
Idiopathic epilepsy is a common human disorder with a strong genetic component, usually exhibiting complex inheritance. We describe a new mouse mutation in C57BL/6J mice, called frequent-flyer (Ff), in which disruption of the gene encoding RNA-bindin
Externí odkaz:
https://doaj.org/article/233cb02082834bcf905e348369b35467