Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nathalie Beaufils"'
Autor:
Philippe Metellus, Clara Camilla, Emilie Bialecki, Nathalie Beaufils, Christine Vellutini, Eric Pellegrino, Pascale Tomasini, Manmeet S. Ahluwalia, Alireza Mansouri, Isabelle Nanni, L’Houcine Ouafik
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundOncogenic fusions of neurotrophic receptor tyrosine kinase NTRK1, NTRK2, or NTRK3 genes have been found in different types of solid tumors. The treatment of patients with TRK fusion cancer with a first-generation TRK inhibitor (such as laro
Externí odkaz:
https://doaj.org/article/ed3fc3c4abd840519e77be3825438190
Autor:
Eric Pellegrino, Coralie Jacques, Nathalie Beaufils, Isabelle Nanni, Antoine Carlioz, Philippe Metellus, L’Houcine Ouafik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Since 2017, we have used IonTorrent NGS platform in our hospital to diagnose and treat cancer. Analyzing variants at each run requires considerable time, and we are still struggling with some variants that appear correct on the metrics at fi
Externí odkaz:
https://doaj.org/article/f2cc208aa9504b5da4bddc6b83fc1c28
Autor:
Eric Pellegrino, Clara Camilla, Norman Abbou, Nathalie Beaufils, Christel Pissier, Jean Gabert, Isabelle Nanni-Metellus, L’Houcine Ouafik
Publikováno v:
Bioengineering, Vol 10, Iss 7, p 753 (2023)
The advent of next-generation sequencing (NGS) technologies has revolutionized the field of bioinformatics and genomics, particularly in the area of onco-somatic genetics. NGS has provided a wealth of information about the genetic changes that underl
Externí odkaz:
https://doaj.org/article/1a0d166be1784b5a9a0992983e8fc0db
Autor:
Zohra Benyahia, Caroline Gaudy-Marqueste, Caroline Berenguer-Daizé, Norhimane Chabane, Nadège Dussault, Mylène Cayol, Christine Vellutini, Amina Djemli, Isabelle Nanni, Nathalie Beaufils, Kamel Mabrouk, Jean-Jacques Grob, L’Houcine Ouafik
Publikováno v:
Cancers, Vol 14, Iss 23, p 5909 (2022)
Introduction: Metastatic melanoma is an aggressive tumor and can constitute a real therapeutic challenge despite the significant progress achieved with targeted therapies and immunotherapies, thus highlighting the need for the identification of new t
Externí odkaz:
https://doaj.org/article/335764c411eb418d867c606f20fbd4cc
Autor:
Diane Frankel, Isabelle Nanni, L’Houcine Ouafik, Clara Camilla, Eric Pellegrino, Nathalie Beaufils, Laurent Greillier, Hervé Dutau, Philippe Astoul, Elise Kaspi, Patrice Roll
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10556 (2022)
The detection of ROS1 and ALK rearrangements is performed for advanced-stage non-small cell lung cancer. Several techniques can be used on cytological samples, such as immunocytochemistry (ICC), fluorescence in situ hybridization (FISH) and, more rec
Externí odkaz:
https://doaj.org/article/40a3684ae64248fcbc5edd2cceec0b33
Autor:
Estelle Menu, Nathalie Beaufils, Fabrice Usseglio, Estelle Balducci, Marina Lafage Pochitaloff, Regis Costello, Jean Gabert
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-5 (2017)
Abstract Background A large number of chromosomal translocations of the human KMT2A gene, better known as the MLL gene, have so far been characterized. Genetic rearrangements involving KMT2A gene are frequently involved in lymphoid, myeloid and mixed
Externí odkaz:
https://doaj.org/article/32ab7b4fb0904286895a5fdb88e7f3e1
Autor:
Eric Pellegrino, Theo Brunet, Christel Pissier, Clara Camilla, Norman Abbou, Nathalie Beaufils, Isabelle Nanni-Metellus, Philippe Métellus, L’Houcine Ouafik
Publikováno v:
BioMedInformatics
BioMedInformatics, 2022, 2 (2), pp.244-267. ⟨10.3390/biomedinformatics2020016⟩
BioMedInformatics; Volume 2; Issue 2; Pages: 244-267
BioMedInformatics, 2022, 2 (2), pp.244-267. ⟨10.3390/biomedinformatics2020016⟩
BioMedInformatics; Volume 2; Issue 2; Pages: 244-267
BRCA1 and BRCA2 are genes with tumor suppressor activity, and they are involved ina considerable number of biological processes allowing the regulation of the cellreplication cycle. A mutation in one of these two genes has a significant probability o
Autor:
Eric Pellegrino, Coralie Jacques, Nathalie Beaufils, Isabelle Nanni, Antoine Carlioz, Philippe Metellus, L’Houcine Ouafik
Motivation: Since 2017, we are using IonTorrent NGS platform in our hospital in order to diagnose cancer and treatment. Analysis variants at each run take us a longtime and we are still struggling with some variants which look correct on the first lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41db2db943c53244be1d3e67e29d80f8
https://doi.org/10.21203/rs.3.rs-426134/v1
https://doi.org/10.21203/rs.3.rs-426134/v1
Publikováno v:
Journal of Molecular Diagnostics
Journal of Molecular Diagnostics, 2017, 19 (1), pp.92-98. ⟨10.1016/j.jmoldx.2016.08.006⟩
Journal of Molecular Diagnostics, American Society for Investigative Pathology (ASIP), 2017, 19 (1), pp.92-98. ⟨10.1016/j.jmoldx.2016.08.006⟩
Journal of Molecular Diagnostics, 2017, 19 (1), pp.92-98. ⟨10.1016/j.jmoldx.2016.08.006⟩
Journal of Molecular Diagnostics, American Society for Investigative Pathology (ASIP), 2017, 19 (1), pp.92-98. ⟨10.1016/j.jmoldx.2016.08.006⟩
International audience; Myeloproliferative neoplasms are clonal hematopoietic stem cell disorders characterized by aberrant proliferation and an increased tendency toward leukemic transformation. The genes JAK2, MPL, and CALR are frequently altered i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40075e66440e9ab7faa536d750fff04
https://hal-amu.archives-ouvertes.fr/hal-01766867/document
https://hal-amu.archives-ouvertes.fr/hal-01766867/document
Autor:
Geoffroy Venton, P. Poulin, Pascal Rihet, Nathalie Beaufils, R. Ragheb, N. Bonnet, Jean Gabert, Vadim Ivanov, Cédric Mercier, Béatrice Loriod, Régis Costello, Pierre Suchon, Rabie Chelbi, Brigitte Kahn-Perlès, T. Le Treut
Publikováno v:
Archives of Dermatological Research
Archives of Dermatological Research, 2017, 309 (8), pp.611-623. ⟨10.1007/s00403-017-1761-0⟩
Archives of Dermatological Research, Springer Verlag, 2017, 309 (8), pp.611-623. ⟨10.1007/s00403-017-1761-0⟩
Archives of Dermatological Research, 2017, 309 (8), pp.611-623. ⟨10.1007/s00403-017-1761-0⟩
Archives of Dermatological Research, Springer Verlag, 2017, 309 (8), pp.611-623. ⟨10.1007/s00403-017-1761-0⟩
International audience; SAHA (vorinostat) is a histone deacetylase inhibitor approved by the USA Food and Drug Administration (FDA) for treating advanced refractory cutaneous T cell lymphomas. As SAHA alters the expression of many genes under control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc725f3a2a7b9763fb1fa90374b0aa07
https://hal-amu.archives-ouvertes.fr/hal-01595894/document
https://hal-amu.archives-ouvertes.fr/hal-01595894/document