Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Nathalie Andrieu"'
Autor:
Carine Dufau, Matthieu Genais, Elodie Mucher, Benjamin Jung, Virginie Garcia, Anne Montfort, Marie Tosolini, Christopher J. Clarke, Jeffrey A. Medin, Thierry Levade, Jean-Pierre Delord, Nicolas Meyer, Vera Pancaldi, Nathalie Andrieu-Abadie, Bruno Ségui
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAdvanced cutaneous melanoma is a skin cancer characterized by a poor prognosis and high metastatic potential. During metastatic spread, melanoma cells often undergo dedifferentiation toward an invasive phenotype, resulting in reduced expr
Externí odkaz:
https://doaj.org/article/d8ca984e4b7d4b01acaea19c7e1a7fdf
Autor:
Mireia Casasampere, Johnson Ung, Alejandro Iñáñez, Carine Dufau, Kazuhito Tsuboi, Josefina Casas, Su-Fern Tan, David J. Feith, Nathalie Andrieu-Abadie, Bruno Segui, Thomas P. Loughran, Jr., José Luis Abad, Gemma Fabrias
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100520- (2024)
Lipid amidases of therapeutic relevance include acid ceramidase (AC), N-acylethanolamine-hydrolyzing acid amidase, and fatty acid amide hydrolase (FAAH). Although fluorogenic substrates have been developed for the three enzymes and high-throughput me
Externí odkaz:
https://doaj.org/article/cbc54b7eb8e74f508add3ca8fe1b0079
Autor:
Justine Noujarède, Lorry Carrié, Virginie Garcia, Maxime Grimont, Anaïs Eberhardt, Elodie Mucher, Matthieu Genais, Anne Schreuder, Stéphane Carpentier, Bruno Ségui, Laurence Nieto, Thierry Levade, Susana Puig, Teresa Torres, Josep Malvehy, Olivier Harou, Jonathan Lopez, Stéphane Dalle, Julie Caramel, Laure Gibot, Joëlle Riond, Nathalie Andrieu-Abadie
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113586- (2023)
Summary: Melanoma is the deadliest form of skin cancer due to its propensity to metastasize. It arises from melanocytes, which are attached to keratinocytes within the basal epidermis. Here, we hypothesize that, in addition to melanocyte-intrinsic mo
Externí odkaz:
https://doaj.org/article/ef232163d25a461ab0d0fdfe5ad159f7
Autor:
Caroline Imbert, Anne Montfort, Marine Fraisse, Elie Marcheteau, Julia Gilhodes, Elodie Martin, Florie Bertrand, Marlène Marcellin, Odile Burlet-Schiltz, Anne Gonzalez de Peredo, Virginie Garcia, Stéphane Carpentier, Sophie Tartare-Deckert, Pierre Brousset, Philippe Rochaix, Florent Puisset, Thomas Filleron, Nicolas Meyer, Laurence Lamant, Thierry Levade, Bruno Ségui, Nathalie Andrieu-Abadie, Céline Colacios
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
There are many patients who do not respond to immune checkpoint inhibitor (ICI) immunotherapy. Here, the authors show a significant negative correlation between sphingosine kinase-1 (SK1) expression and survival for ICI-treated melanoma patients, and
Externí odkaz:
https://doaj.org/article/38bb744217484cb7ab770593454d6238
Autor:
Anne Montfort, Carine Dufau, Céline Colacios, Nathalie Andrieu-Abadie, Thierry Levade, Thomas Filleron, Jean-Pierre Delord, Maha Ayyoub, Nicolas Meyer, Bruno Ségui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-4 (2019)
Abstract Immune checkpoint blockers (ICB) have revolutionized cancer therapy. However, complete response is observed in a minority of patients and most patients develop immune-related adverse events (irAEs). These include colitis, which can be treate
Externí odkaz:
https://doaj.org/article/3e240457042741c09966d9f459323c66
Autor:
Florie Bertrand, Anne Montfort, Elie Marcheteau, Caroline Imbert, Julia Gilhodes, Thomas Filleron, Philippe Rochaix, Nathalie Andrieu-Abadie, Thierry Levade, Nicolas Meyer, Céline Colacios, Bruno Ségui
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Most melanoma patients do not respond to anti-PD1 therapy. Here, the authors show that TNFα blockade synergizes with anti-PD-1 by preventing anti-PD-1-induced CD8+ T cell death and TIM-3 expression on such cells.
Externí odkaz:
https://doaj.org/article/a4452c1e969c432987f7e542b52dfbb2
Autor:
Anne Montfort, Céline Colacios, Thierry Levade, Nathalie Andrieu-Abadie, Nicolas Meyer, Bruno Ségui
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/66e261d3ab07439990fbae3e35d88881
Autor:
Anne Montfort, Céline Colacios, Thierry Levade, Nathalie Andrieu-Abadie, Nicolas Meyer, Bruno Ségui
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/49f0aadf942f4feeb45efca82477dadb
Autor:
Fatima Bilal, Anne Montfort, Julia Gilhodes, Virginie Garcia, Joëlle Riond, Stéphane Carpentier, Thomas Filleron, Céline Colacios, Thierry Levade, Ahmad Daher, Nicolas Meyer, Nathalie Andrieu-Abadie, Bruno Ségui
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Sphingolipid (SL) metabolism alterations have been frequently reported in cancer including in melanoma, a bad-prognosis skin cancer. In normal cells, de novo synthesized ceramide is mainly converted to sphingomyelin (SM), the most abundant SL, by sph
Externí odkaz:
https://doaj.org/article/35281e352b514bb2bdc159ba35de8093
Autor:
Lorry Carrié, Mathieu Virazels, Carine Dufau, Anne Montfort, Thierry Levade, Bruno Ségui, Nathalie Andrieu-Abadie
Publikováno v:
Cells, Vol 9, Iss 9, p 1967 (2020)
Cutaneous melanoma is a deadly skin cancer whose aggressiveness is directly linked to its metastatic potency. Despite remarkable breakthroughs in term of treatments with the emergence of targeted therapy and immunotherapy, the prognosis for metastati
Externí odkaz:
https://doaj.org/article/c90d0161cfcc4d548806e0c5660acc4a