Výsledky vyhledávání - "Nathalie, Wacht"

Supplementary Figures S1-S5 from BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation

Autor: Alexander Egle, Richard Greil, Tanja N. Hartmann, Andreas Villunger, Nadja Zaborsky, Bettina Jansko, Clemens Hufnagl, Nicole Maeding, Yuan Qi, Michael Leisch, Nathalie Wacht, Daniela Asslaber

Supplementary Figures S1-S5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad407808d33edf6eef105324e7b2fe7
https://doi.org/10.1158/1078-0432.22471884.v1

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Data from BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation

Autor: Alexander Egle, Richard Greil, Tanja N. Hartmann, Andreas Villunger, Nadja Zaborsky, Bettina Jansko, Clemens Hufnagl, Nicole Maeding, Yuan Qi, Michael Leisch, Nathalie Wacht, Daniela Asslaber

Purpose:Chronic lymphocytic leukemia (CLL) pathophysiology is characterized by a complex crosstalk of tumor cells with the microenvironment. In this regard, NF-κB signaling is considered as important signaling axis, with a variety of key molecules a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2630da3f9d678951e655180b8808779c
https://doi.org/10.1158/1078-0432.c.6528042

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BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation

Autor: Daniela, Asslaber, Nathalie, Wacht, Michael, Leisch, Yuan, Qi, Nicole, Maeding, Clemens, Hufnagl, Bettina, Jansko, Nadja, Zaborsky, Andreas, Villunger, Tanja N, Hartmann, Richard, Greil, Alexander, Egle

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(6)

Chronic lymphocytic leukemia (CLL) pathophysiology is characterized by a complex crosstalk of tumor cells with the microenvironment. In this regard, NF-κB signaling is considered as important signaling axis, with a variety of key molecules aberrantl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21464166f8ab722d7654b9d73b1fa175
https://pubmed.ncbi.nlm.nih.gov/30487125

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Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia

Autor: Richard Greil, Michael Steurer, E Sifft, Olaf Merkel, Nathalie Wacht, Frank Hamacher, Thomas Kocher, Thomas Melchardt, Josefina Piñón Hofbauer, Michaela Schlederer, Alexander Egle, Lukas Kenner, Ursula Denk, Marcel Scheideler

Publikováno v: Leukemia. 26(12)

Chronic lymphocytic leukemia (CLL) is the most prevalent lymphoid malignancy in the elderly of the Western world. Although treatment options have improved over the past two decades, 10-15% of patients still have a poor prognosis and are often resista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbb7cc2001b3bec4603edefc965ff6e
https://pubmed.ncbi.nlm.nih.gov/22743622

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Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target

Autor: Martin Hermann, Eva Maizner, Johann Kern, Marcel Scheideler, Marlene Obkircher, Nathalie Wacht, Olaf Merkel, Karin Jöhrer, Frank Hamacher, Claudia Zelle-Rieser, Johanna Parteli, Richard Greil, Daniel Neureiter, Christian Zidorn

Publikováno v: Journal of molecular medicine (Berlin, Germany). 90(6)

Despite recent advances in therapy, multiple myeloma, the second most common hematologic tumor in the Western world, is still incurable. Identification of substances that display a wide range of tumor-killing activities and target cancer-specific pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2992e9e4e1dd4b64d1cdb8c9d1ece9a
https://pubmed.ncbi.nlm.nih.gov/22205266

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Ferritin--a mediator of apoptosis?

Autor: Friedrich Lottspeich, Ingo Ohlenschläger, Nathalie Wacht, Nikolaus Bresgen, Paolo Arosio, Bettina Dunkelmann, Elisabeth Kuffner, Peter Eckl, Brigitte Fiedler, Susanne Zach

Previously we have demonstrated an apoptosis inducing activity for a rat hepatocyte conditioned medium (CM) presumably mediated by acidic isoferritins. Here, we present support for this assumption since isoferritins purified from different rat hepato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991fb0c84b52dbc32d5e706188029066
http://hdl.handle.net/11379/21426

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Abstract 603: CAL-101 acts synergistic with arsenic trioxide in chronic lymphocytic leukemia by preventing p21 phosphorylation through AKT1

Autor: Nathalie Wacht, Richard Greil, Eveline Sifft, Daniela Asslaber, Simone Schweiggl, Olaf Merkel

Publikováno v: Cancer Research. 73:603-603

Chronic lymphocytic leukemia (CLL) is the most abundant leukemia of the elderly in the Western world and characterized by the accumulation of CD5/CD19/CD23 positive cells in the peripheral blood, lymph nodes and spleen. It has a very heterogeneous co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9f076d8a7fe0f855276e506f5da0ac4
https://doi.org/10.1158/1538-7445.am2013-603

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