Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Nathalie, Poupin"'
Autor:
Louison Fresnais, Olivier Perin, Anne Riu, Romain Grall, Alban Ott, Bernard Fromenty, Jean-Clément Gallardo, Maximilian Stingl, Clément Frainay, Fabien Jourdan, Nathalie Poupin
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-32 (2024)
Abstract Background The growing abundance of in vitro omics data, coupled with the necessity to reduce animal testing in the safety assessment of chemical compounds and even eliminate it in the evaluation of cosmetics, highlights the need for adequat
Externí odkaz:
https://doaj.org/article/f6f5cfe4075a4c539bfffd1a4d014ba0
Autor:
Cecilia Wieder, Juliette Cooke, Clement Frainay, Nathalie Poupin, Russell Bowler, Fabien Jourdan, Katerina J Kechris, Rachel Pj Lai, Timothy Ebbels
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 3, p e1011814 (2024)
As terabytes of multi-omics data are being generated, there is an ever-increasing need for methods facilitating the integration and interpretation of such data. Current multi-omics integration methods typically output lists, clusters, or subnetworks
Externí odkaz:
https://doaj.org/article/d2cc81da3c5e4dfc905dda29ad6a12c4
Autor:
Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011381 (2024)
Metabolic profiling (metabolomics) aims at measuring small molecules (metabolites) in complex samples like blood or urine for human health studies. While biomarker-based assessment often relies on a single molecule, metabolic profiling combines sever
Externí odkaz:
https://doaj.org/article/addb1baefa6e45aa91346ae67d1b18df
Autor:
Raquel Chamorro-García, Nathalie Poupin, Marie Tremblay-Franco, Cécile Canlet, Riann Egusquiza, Roselyne Gautier, Isabelle Jouanin, Bassem M. Shoucri, Bruce Blumberg, Daniel Zalko
Publikováno v:
Environment International, Vol 157, Iss , Pp 106822- (2021)
Background: Endocrine disrupting chemicals (EDCs) contribute to the etiology of metabolic disorders such as obesity, insulin resistance and hepatic dysfunction. Concern is growing about the consequences of perinatal EDC exposure on disease predisposi
Externí odkaz:
https://doaj.org/article/1b4a9048bf254c588c7c4fc920791431
Autor:
Cecilia Wieder, Clément Frainay, Nathalie Poupin, Pablo Rodríguez-Mier, Florence Vinson, Juliette Cooke, Rachel Pj Lai, Jacob G Bundy, Fabien Jourdan, Timothy Ebbels
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009105 (2021)
Over-representation analysis (ORA) is one of the commonest pathway analysis approaches used for the functional interpretation of metabolomics datasets. Despite the widespread use of ORA in metabolomics, the community lacks guidelines detailing its be
Externí odkaz:
https://doaj.org/article/38f5454156524f19b62777d46227717a
Autor:
Blandine Comte, Stéphanie Monnerie, Marion Brandolini-Bunlon, Cécile Canlet, Florence Castelli, Emeline Chu-Van, Benoit Colsch, François Fenaille, Charlotte Joly, Fabien Jourdan, Natacha Lenuzza, Bernard Lyan, Jean-François Martin, Carole Migné, José A. Morais, Mélanie Pétéra, Nathalie Poupin, Florence Vinson, Etienne Thevenot, Christophe Junot, Pierrette Gaudreau, Estelle Pujos-Guillot
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103440- (2021)
Background: Metabolic syndrome (MetS), a cluster of factors associated with risks of developing cardiovascular diseases, is a public health concern because of its growing prevalence. Considering the combination of concomitant components, their develo
Externí odkaz:
https://doaj.org/article/79faa2aac5e74902966d3e182affd49f
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008730 (2021)
The correct identification of metabolic activity in tissues or cells under different conditions can be extremely elusive due to mechanisms such as post-transcriptional modification of enzymes or different rates in protein degradation, making difficul
Externí odkaz:
https://doaj.org/article/04622044e7ec49318f686160518f093d
Autor:
Karla Fabiola Corral-Jara, Laura Cantini, Nathalie Poupin, Tao Ye, Jean Paul Rigaudière, Sarah De Saint Vincent, Alexandre Pinel, Béatrice Morio, Frédéric Capel
Publikováno v:
Nutrients, Vol 12, Iss 12, p 3864 (2020)
Insulin resistance decreases the ability of insulin to inhibit hepatic gluconeogenesis, a key step in the development of metabolic syndrome. Metabolic alterations, fat accumulation, and fibrosis in the liver are closely related and contribute to the
Externí odkaz:
https://doaj.org/article/3b14cfa6e6e64211b2de89f3fbef58d2
Autor:
Joran Villaret-Cazadamont, Nathalie Poupin, Anthony Tournadre, Aurélie Batut, Lara Gales, Daniel Zalko, Nicolas J. Cabaton, Floriant Bellvert, Justine Bertrand-Michel
Publikováno v:
Metabolites, Vol 10, Iss 12, p 490 (2020)
The authors wish to make the following comment to the paper [...]
Externí odkaz:
https://doaj.org/article/9a25db7f51ba4fb49d819005a6f563b2
Autor:
Joran Villaret-Cazadamont, Nathalie Poupin, Anthony Tournadre, Aurélie Batut, Lara Gales, Daniel Zalko, Nicolas J. Cabaton, Floriant Bellvert, Justine Bertrand-Michel
Publikováno v:
Metabolites, Vol 10, Iss 9, p 338 (2020)
The functional understanding of metabolic changes requires both a significant investigation into metabolic pathways, as enabled by global metabolomics and lipidomics approaches, and the comprehensive and accurate exploration of specific key pathways.
Externí odkaz:
https://doaj.org/article/5bd9ab41d5dd4c7489d50c98ef7bc21f