Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Nathalie, Deboosere"'
Autor:
Sandrine Belouzard, Arnaud Machelart, Valentin Sencio, Thibaut Vausselin, Eik Hoffmann, Nathalie Deboosere, Yves Rouillé, Lowiese Desmarets, Karin Séron, Adeline Danneels, Cyril Robil, Loic Belloy, Camille Moreau, Catherine Piveteau, Alexandre Biela, Alexandre Vandeputte, Séverine Heumel, Lucie Deruyter, Julie Dumont, Florence Leroux, Ilka Engelmann, Enagnon Kazali Alidjinou, Didier Hober, Priscille Brodin, Terence Beghyn, François Trottein, Benoit Deprez, Jean Dubuisson
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010498 (2022)
Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those exhibiting antiviral activity against
Externí odkaz:
https://doaj.org/article/ef24a1fe221949deb66833f87060787b
Autor:
Dimitri Juillot, Charlène Cornilleau, Nathalie Deboosere, Cyrille Billaudeau, Parfait Evouna-Mengue, Véronique Lejard, Priscille Brodin, Rut Carballido-López, Arnaud Chastanet
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT How cells control their shape and size is a fundamental question of biology. In most bacteria, cell shape is imposed by the peptidoglycan (PG) polymeric meshwork that surrounds the cell. Thus, bacterial cell morphogenesis results from the co
Externí odkaz:
https://doaj.org/article/1c1a70d210fe45f8a49b5468ec40c118
Autor:
Fadel Sayes, Catherine Blanc, Louis S. Ates, Nathalie Deboosere, Mickael Orgeur, Fabien Le Chevalier, Matthias I. Gröschel, Wafa Frigui, Ok-Ryul Song, Richard Lo-Man, Florence Brossier, Wladimir Sougakoff, Daria Bottai, Priscille Brodin, Pierre Charneau, Roland Brosch, Laleh Majlessi
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1072-1084 (2018)
Summary: The pathogenic potential of Mycobacterium tuberculosis largely depends on ESX secretion systems exporting members of the multigenic Esx, Esp, and PE/PPE protein families. To study the secretion and regulation patterns of these proteins while
Externí odkaz:
https://doaj.org/article/1d85853904c84b0698247d51802126df
Autor:
Charlène Cornilleau, Cyrille Billaudeau, Priscille Brodin, Dimitri Juillot, Véronique Léjard, Rut Carballido-López, Arnaud Chastanet, Parfait Evouna-Mengue, Nathalie Deboosere
How cells control their shape and size is a fundamental question of biology. In most bacteria, cell shape is imposed by the peptidoglycan (PG) polymeric meshwork that surrounds the cell. Thus, bacterial cell morphogenesis results from the coordinated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e742766c79c9726019c75625fbc54d
https://hal.inrae.fr/hal-03370372
https://hal.inrae.fr/hal-03370372
Autor:
Nathalie, Deboosere, Imène, Belhaouane, Arnaud, Machelart, Eik, Hoffmann, Alexandre, Vandeputte, Priscille, Brodin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2314
Mycobacterium tuberculosis is able to colonize, persist, and massively replicate in host cells, such as phagocytes and epithelial cells. The intracellular stage of the bacteria is critical to the development of tuberculosis pathogenesis. The detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1baafe775a85ba938ba7ce8db5ecf366
https://pubmed.ncbi.nlm.nih.gov/34235675
https://pubmed.ncbi.nlm.nih.gov/34235675
Autor:
Ok-Ryul Song, Han-Byul Kim, Samuel Jouny, Isabelle Ricard, Alexandre Vandeputte, Nathalie Deboosere, Estelle Marion, Christophe J. Queval, Pierre Lesport, Emmanuel Bourinet, Daniel Henrion, Seog Bae Oh, Guillaume Lebon, Guillaume Sandoz, Edouard Yeramian, Laurent Marsollier, Priscille Brodin
Publikováno v:
Toxins, Vol 9, Iss 7, p 227 (2017)
Mycolactone, a polyketide molecule produced by Mycobacterium ulcerans, is the etiological agent of Buruli ulcer. This lipid toxin is endowed with pleiotropic effects, presents cytotoxic effects at high doses, and notably plays a pivotal role in host
Externí odkaz:
https://doaj.org/article/35df8b7d9e484cd0b69356dfb3cafe7b
Autor:
Arnaud Machelart, Eik Hoffmann, Alexandre Vandeputte, Imène Belhaouane, Nathalie Deboosere, Priscille Brodin
Publikováno v:
Methods in Molecular Biology ISBN: 9781071614594
Mycobacterium tuberculosis is able to colonize, persist, and massively replicate in host cells, such as phagocytes and epithelial cells. The intracellular stage of the bacteria is critical to the development of tuberculosis pathogenesis. The detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0564df119dc3a1fdde1ba2a647ef59
https://doi.org/10.1007/978-1-0716-1460-0_29
https://doi.org/10.1007/978-1-0716-1460-0_29
Autor:
Thibaut Vausselin, Adeline Danneels, Lowiese Desmarets, Arnaud Machelart, Severine Heumel, Valentin Sencio, Lucie Deruyter, Yves Rouillé, Enagnon Kazali Alidjinou, Cyril Robil, Didier Hober, Sandrine Belouzard, Alexandre Biela, Alexandre Vandeputte, Benoit Deprez, Julie Dumont, Catherine Piveteau, Nathalie Deboosere, Eik Hoffmann, Camille Moreau, François Trottein, Terence Beghyn, Jean Dubuisson, Karin Séron, Florence Leroux, Loic Belloy, Ilka Engelmann, Priscille Brodin
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2022, 18 (5), pp.e1010498. ⟨10.1371/journal.ppat.1010498⟩
PLoS Pathogens, 2022, ⟨10.1371/journal.ppat.1010498⟩
PLoS Pathogens, 2022, 18 (5), pp.e1010498. ⟨10.1371/journal.ppat.1010498⟩
PLoS Pathogens, 2022, ⟨10.1371/journal.ppat.1010498⟩
Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those exhibiting antiviral activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517ce45f1b7ce4e7f5acb50a0202a1e4
https://doi.org/10.1371/journal.ppat.1010498
https://doi.org/10.1371/journal.ppat.1010498
Autor:
Garrett C. Moraski, Nathalie Deboosere, Anne J. Lenaerts, Courtney Hastings, Alexandre Vandeputte, Priscille Brodin, Heath A. Weaver, Lisa K. Woolhiser, Marvin J. Miller, Kate L. Marshall
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227224 (2020)
PLoS ONE
PLoS ONE, 2020, 15 (1), pp.e0227224. ⟨10.1371/journal.pone.0227224⟩
PLoS ONE, Public Library of Science, 2020, 15 (1), pp.e0227224. ⟨10.1371/journal.pone.0227224⟩
PLoS ONE
PLoS ONE, 2020, 15 (1), pp.e0227224. ⟨10.1371/journal.pone.0227224⟩
PLoS ONE, Public Library of Science, 2020, 15 (1), pp.e0227224. ⟨10.1371/journal.pone.0227224⟩
International audience; The imidazo[2,1-b]thiazole-5-carboxamides (ITAs) are a promising class of anti-tuberculosis agents shown to have potent activity in vitro and to target QcrB, a key component of the mycobacterial cytochrome bcc-aa3 super comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7445a2681f62d5993b3bd2184801ffd7
https://doaj.org/article/042e2cff077d4254a8081fbb634cbcd3
https://doaj.org/article/042e2cff077d4254a8081fbb634cbcd3
Autor:
Clara Franch, Rosangela Frita, Joel S. Freundlich, Alexandre Vandeputte, Maria Rosalia Pasca, Courtney Veilleux, Mohamad Sabbah, Rajiv Kumar Jha, Beatrice Silvia Orena, Eik Hoffmann, Katarína Mikušová, Liliana Rodrigues, Adwait Anand Godbole, Lesley A. Mitchenall, Pradeep Kumar, Valakunja Nagaraja, Nathalie Deboosere, Stanislav Huszár, Priscille Brodin, Clara Aguilar-Pérez, José A. Aínsa, Sean Ekins, Riccardo Russo, Nancy D. Connell, Anthony Maxwell, Júlia Zemanová, Martin Forbak, Thomas J. Lane, Giorgia Mori
Publikováno v:
Tuberculosis. 112:98-109
The search for compounds with biological activity for many diseases is turning increasingly to drug repurposing. In this study, we have focused on the European Union-approved antimalarial pyronaridine which was found to have in vitro activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1ba750c5c3cc0488b8f132f5da37c7
https://doi.org/10.1016/j.tube.2018.08.004
https://doi.org/10.1016/j.tube.2018.08.004