Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nathalia M. De Vasconcelos"'
Autor:
Marianna Ioannou, Dennis Hoving, Iker Valle Aramburu, Mia I. Temkin, Nathalia M. De Vasconcelos, Theodora-Dorita Tsourouktsoglou, Qian Wang, Stefan Boeing, Robert Goldstone, Spyros Vernardis, Vadim Demichev, Markus Ralser, Sascha David, Klaus Stahl, Christian Bode, Venizelos Papayannopoulos
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
Hyperinflammation and immune dysfunction are key drivers of immunopathology in sepsis. Here the authors show microbial exploitation of phagocytic receptors is linked to triggering of sepsis and the immune cell mediated reduction in neutrophil life sp
Externí odkaz:
https://doaj.org/article/16a60dd84fd94a0a9691874f1193e9ac
Autor:
Nina Van Opdenbosch, Hanne Van Gorp, Maarten Verdonckt, Pedro H.V. Saavedra, Nathalia M. de Vasconcelos, Amanda Gonçalves, Lieselotte Vande Walle, Dieter Demon, Magdalena Matusiak, Filip Van Hauwermeiren, Jinke D’Hont, Tino Hochepied, Stefan Krautwald, Thirumala-Devi Kanneganti, Mohamed Lamkanfi
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3427-3444 (2017)
Summary: The caspase activation and recruitment domain (CARD)-based inflammasome sensors NLRP1b and NLRC4 induce caspase-1-dependent pyroptosis independent of the inflammasome adaptor ASC. Here, we show that NLRP1b and NLRC4 trigger caspase-8-mediate
Externí odkaz:
https://doaj.org/article/a03de55f3cff4bf0b903b77a4609b2e2
Autor:
Iker Valle Aramburu, Dennis Hoving, Spyros I. Vernardis, Martha C.F. Tin, Marianna Ioannou, Mia I. Temkin, Nathalia M. De Vasconcelos, Vadim Demichev, Elisa Theresa Helbig, Lena Lippert, Klaus Stahl, Matthew White, Helena Radbruch, Jana Ihlow, David Horst, Scott T. Chiesa, John E. Deanfield, Sascha David, Christian Bode, Florian Kurth, Markus Ralser, Venizelos Papayannopoulos
Publikováno v:
Immunity.
The factors that influence survival during severe infection are unclear. Extracellular chromatin drives pathology, but the mechanisms enabling its accumulation remain elusive. Here, we show that in murine sepsis models, splenocyte death interferes wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb7c37ea9968e1b82df1092e391006b
https://pubmed.ncbi.nlm.nih.gov/36462503
https://pubmed.ncbi.nlm.nih.gov/36462503
Autor:
Venizelos Papayannopoulos, Marianna Ioannou, Mia I. Temkin, Klaus Stahl, Spyros I. Vernardis, Sascha David, Dennis Hoving, Nathalia M. De Vasconcelos, Iker Valle Aramburu, Markus Ralser, Theodora-Dorita Tsourouktsoglou, Stefan Boeing, Christian Bode, Qian Wang, Robert L. Goldstone, Vadim Demichev
SummaryThe mechanisms regulating immune dysfunction during sepsis are poorly understood. Here, we show that neutrophil-derived myeloperoxidase delays the onset of immune dysfunction during systemic candidiasis by controlling microbes captured by sple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e352b8c222ee6d3768c2578fc128d6e2
https://doi.org/10.1101/2021.08.09.455510
https://doi.org/10.1101/2021.08.09.455510
Autor:
Maísa B. Costa, José R. Corrêa, Heibbe C. B. de Oliveira, Diego C. B. D. Santos, Pedro H. P. R. Carvalho, Rafael G. Silva, Claudia C. Gatto, Nathalia M. de Vasconcelos, Luciana M. Ramos, Brenno A. D. Neto
Publikováno v:
RSC Adv.. 2:1524-1532
The present manuscript describes the synthesis of two novel 2,1,3-benzothiadiazole (BTD) derivatives containing an excited state intramolecular proton transfer (ESIPT) site. Photophysical properties, X-ray analysis, ESIPT and intramolecular charge-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774c650ecdd4368412f2bbb0ad9efc6a
https://doi.org/10.1039/c1ra00701g
https://doi.org/10.1039/c1ra00701g