Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nathalia G. Amado"'
Autor:
Nathalia G. Amado, Elena D. Nosyreva, David Thompson, Thomas J. Egeland, Osita W. Ogujiofor, Michelle Yang, Alexandria N. Fusco, Niccolo Passoni, Jeremy Mathews, Brandi Cantarel, Linda A. Baker, Ruhma Syeda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Prune belly syndrome (PBS), also known as Eagle-Barret syndrome, is a rare, multi-system congenital myopathy primarily affecting males. Phenotypically, PBS cases manifest three cardinal pathological features: urinary tract dilation with poor
Externí odkaz:
https://doaj.org/article/7bd21536524647f0961f08073f5b8d4b
Autor:
Danilo Predes, Lorena A. Maia, Isadora Matias, Hannah Paola Mota Araujo, Carolina Soares, Fernanda G. Q. Barros-Aragão, Luiz F. S. Oliveira, Renata R. Reis, Nathalia G. Amado, Alessandro B. C. Simas, Fabio A. Mendes, Flávia C. A. Gomes, Claudia P. Figueiredo, Jose G. Abreu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12078 (2022)
The Wnt/β-catenin signaling pathway dictates cell proliferation and differentiation during embryonic development and tissue homeostasis. Its deregulation is associated with many pathological conditions, including neurodegenerative disease, frequentl
Externí odkaz:
https://doaj.org/article/b6e7926c111541fdb55d182315a0acfc
Publikováno v:
The International Journal of Developmental Biology. 65:227-233
This review highlights the work that my research group has been developing, together with international collaborators, during the last decade. Since we were able to establish the Xenopus laevis experimental model in Brazil, we have been focused on un
Autor:
Alexandria N. Fusco, Jeremy A. Mathews, Linda A. Baker, Nathalia G. Amado, Brandi L. Cantarel, Thomas J. Egeland, Caitlin T. Coco
Publikováno v:
Journal of Urology. 206
Autor:
Linda A. Baker, Nathalia G. Amado, Alicia Malewska, Alexandria N. Fusco, Jeremy A. Mathews, Gervaise H. Henry, Thomas J. Egeland, Brandi L. Cantarel, Douglas W. Strand
Publikováno v:
The Journal of urology. 206(Suppl 3)
INTRODUCTION AND OBJECTIVE Prune Belly Syndrome (PBS) is characterized by bladder dysmyogenesis, yielding a dysfunctional compliant thick wall with excess collagen deposition. To dissect the cellular heterogeneity and gene expression networks altered
Autor:
Maorong Chen, Nathalia G. Amado, Jieqiong Tan, José G. Abreu, Mengxu Ge, Alice H. Reis, Xi He
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Wnt signaling through the Frizzled (FZD) family of serpentine receptors is essential for embryogenesis and homeostasis, and stringent control of the FZD protein level is critical for stem cell regulation. Through CRISPR/Cas9 genome-wide screening in
Autor:
Alice H. Reis, Luiz F. S. Oliveira, Carlos A. M. Fraga, Laís S. S. Ferreira, Danilo Predes, Fabio A. Mendes, José G. Abreu, Helena L. Borges, Igor F. de Oliveira, Anderson Faletti, João M A Delou, Ricardo Machado Kuster, Nathalia G. Amado, Lorena A. Maia
Publikováno v:
Cancers
Volume 11
Issue 12
Volume 11
Issue 12
The deregulation of the Wnt/&beta
catenin signaling pathway is a central event in colorectal cancer progression, thus a promising target for drug development. Many natural compounds, such as flavonoids, have been described as Wnt/&beta
cate
catenin signaling pathway is a central event in colorectal cancer progression, thus a promising target for drug development. Many natural compounds, such as flavonoids, have been described as Wnt/&beta
cate
Autor:
Nathalia G. Amado, Daniel Cassiano-Lima, José G. Abreu, Diva Maria Borges-Nojosa, Reinaldo B. Oriá, Ana Valêsca Pinto de Lima, Alice H. Reis
Publikováno v:
genesis. 54:257-271
Direct development in amphibians is characterized by the loss of aquatic breeding. The anuran Adelophryne maranguapensis is one example of a species with direct development, and it is endemic to the state of Ceara, Brazil. Detailed morphological feat
Autor:
Nathalia G. Amado, José G. Abreu, Matthias Zebisch, Bryan T. MacDonald, E. Yvonne Jones, Seong-Moon Cheong, Xi He, Xinjun Zhang, Alice H. Reis
Publikováno v:
Developmental Cell. 32(6):719-730
Summary Secreted Wnt morphogens are essential for embryogenesis and homeostasis and require a lipid/palmitoleoylate modification for receptor binding and activity. Notum is a secreted Wnt antagonist that belongs to the α/β hydrolase superfamily, bu