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pro vyhledávání: '"Natela Churgulia"'
Autor:
Junru Cui, Mesfin Meshesha, Natela Churgulia, Christian Merlo, Edward Fuchs, Jennifer Breakey, Joyce Jones, James T. Stivers
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Although CD4+ memory T cells are considered the primary latent reservoir for HIV-1, replication competent HIV has been detected in tissue macrophages in both animal and human studies. During in vitro HIV infection, the depleted nu
Externí odkaz:
https://doaj.org/article/87d0e096aa8d4fef859f9e376bebbe0b
Autor:
Mesfin Meshesha, Alexandre Esadze, Junru Cui, Natela Churgulia, Sushil Kumar Sahu, James T Stivers
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235012 (2020)
Non-dividing cells of the myeloid lineage such as monocytes and macrophages are target cells of HIV that have low dNTP pool concentrations and elevated levels of dUTP, which leads to frequent incorporation of dUMP opposite to A during reverse transcr
Externí odkaz:
https://doaj.org/article/42026a354a3e4c28bf5b089f30c9b653
Autor:
Junru Cui, Mesfin Meshesha, Alexandre Esadze, Natela Churgulia, Sushil Kumar Sahu, James T. Stivers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235012 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235012 (2020)
Background Non-dividing cells of the myeloid lineage such as monocytes and macrophages are target cells of HIV that have low dNTP pool concentrations and elevated levels of dUTP, which leads to frequent incorporation of dUMP opposite to A during reve